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The map label for this gene is ackA [H]

Identifier: 134302778

GI number: 134302778

Start: 1866047

End: 1867201

Strand: Direct

Name: ackA [H]

Synonym: FTW_1991

Alternate gene names: 134302778

Gene position: 1866047-1867201 (Clockwise)

Preceding gene: 134302777

Following gene: 134302779

Centisome position: 98.29

GC content: 33.94

Gene sequence:

>1155_bases
ATGTCTGAAATATTAGTATTAAATTGCGGTAGTTCTTCAGTTAAGTTTGCACTTATAAATCCACATACTTCACAATCTTT
AGTTACAGGTCTTGCAGAAAACATTGCTACTAAAAATTGTAAAGTAGTTTTTAAAGCTGAGCATAAAATTGAAAAGTACC
TTGAGAATGGTAGTTACAAAGATGTATTTGAAATGCTCAAAGATTTTTTGGTAGAGAATAAACATCTAGAAAAGATAGTT
GCAATTGGACATCGGGTAGTTCATGGAGGTCAGTATTTTTCTAAATCGGTACTGATAAATGCTGACTCATTAGAAAAAAT
AAAAGCGTGTATTGCATTAGCGCCATTGCATAATCCAGCACATATTGAGGGTATAAGATTTTGTCAGCAAATATTTCCAG
AATTACCTCAGGTAGCTGTGTTTGATACAGCATTTCATCAGACTATGCCAAGCTATATCGCAGAGTATGCAATACCTTAT
GAGCTTACACACAAGCATAATATTCGTAAATATGGCGCACATGGAACTTCACATAAATATGTCTCAGAGCAGGCAGCAAA
GATCTTAACTCAACAAAAAGCTAATGTCATAGTTGCACATTTAGGTAATGGTTGTAGTATTACAGCTGTTGTTGATGGTA
AAAGTATCGATACTAGTATGGGGCTTACTCCTCTAGATGGACTTGTTATGGGAACACGCTCAGGCTGTATTGACCCTAGT
ATTTTTGCATACATATCCGATAACCTTGATTGGAGTGTCACAGAGATTACAAATATGCTAAACAAGCAAAGTGGTCTATT
AGGTATTTGCGGACATAATGATATGCGCGAAGTTTCTCAACTTGCTGCAAAAGGAGATAGTCTAGCGAAGTTGGCTATAG
AAATCTTCTCTCATAGAGTAGCAAAGTTTGTGGCTAGTTATATGATTTATTTTAATAAGTTAGATGCTTTAGTATTTACA
GGAGGTATTGGTGAGAATGCTGCTAATATCCGTAAAAATATTATTTCAAAGCTAGCAAATCTTGGTTTTATGATAGATCA
TCAAAAAAACTCTAATTCAGAGACATTCATAAACAGCAAAAATAGTCATAATATAATGGTAATAGCGACTAATGAAGAGC
TTATGATTGCTCAAGAAACACAAAATTTAATATAA

Upstream 100 bases:

>100_bases
TGATATAATAAGCATTCTCAAAACACTATACCAAGCTGTCACTATCTTCTAGATTATTATATAATACGGTTATTTCTTAT
TTAAATTTTTTAGTCTAGAT

Downstream 100 bases:

>100_bases
GAGTTTGTTATGAAAAAATCTATATTTATTCTGCCTACTTCAAAACATACCGGTTTACGTTTATTAGCAAGTAGTATGGT
ATATGCATTACAGCAAAAGG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIV
AIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTMPSYIAEYAIPY
ELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
IFAYISDNLDWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFT
GGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI

Sequences:

>Translated_384_residues
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIV
AIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTMPSYIAEYAIPY
ELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
IFAYISDNLDWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFT
GGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI
>Mature_383_residues
SEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIVA
IGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTMPSYIAEYAIPYE
LTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPSI
FAYISDNLDWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFTG
GIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=395, Percent_Identity=45.8227848101266, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI145693184, Length=389, Percent_Identity=41.1311053984576, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42280; Mature: 42149

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYK
CCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCHH
DVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPA
HHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHCCEEEEECHHHHHHHHHHHHCCCCCCH
HIEGIRFCQQIFPELPQVAVFDTAFHQTMPSYIAEYAIPYELTHKHNIRKYGAHGTSHKY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCHHH
VSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
HHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC
IFAYISDNLDWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRV
EEEEEECCCCEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSK
HHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NSHNIMVIATNEELMIAQETQNLI
CCCEEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYK
CCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCHH
DVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPA
HHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHCCEEEEECHHHHHHHHHHHHCCCCCCH
HIEGIRFCQQIFPELPQVAVFDTAFHQTMPSYIAEYAIPYELTHKHNIRKYGAHGTSHKY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCHHH
VSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPS
HHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC
IFAYISDNLDWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRV
EEEEEECCCCEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
AKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSK
HHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NSHNIMVIATNEELMIAQETQNLI
CCCEEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA