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The map label for this gene is glsA [H]

Identifier: 134302697

GI number: 134302697

Start: 1777377

End: 1778918

Strand: Direct

Name: glsA [H]

Synonym: FTW_1896

Alternate gene names: 134302697

Gene position: 1777377-1778918 (Clockwise)

Preceding gene: 134302696

Following gene: 134302698

Centisome position: 93.62

GC content: 34.63

Gene sequence:

>1542_bases
ATGAAAACAATAATGATTAAAACTACATCTTCTAGTGGTGAAGATTACTATAAAAATATTTTTAGCGCTATCTGTGACAA
AGATGGCTTTATGACAAAGACAGATATTCTTGATATCTTAGTTGAGTCAGGTATTAGCAATGATGATCCTCGCATTACTA
AATTAATCGCCAAATTAAATAAATTCTGTGATATTGATAAGATTGATTTTGATACATTTCAAGAAATTACTTTTGAAAAT
ATAGGTCTTATCGAAAAAGCTATTAATAAAGGCTTTATCATTCCCAACTTTAAGGATTTCAAAAAAGAAATTGAAGCCAT
ATATAACGAAACTAAAAAGAATGAAACAGGCAGAAACGCAAACTATATTCCTCAACTAGCAAGGGTTGACCCTAATCTTT
TTGCTGTGGCTTTTTGTAGTGTTGATGGTCAAATAATTACCTTAGGAGATTATCTACAACCATACTGTGTACAATCAACT
GCAAAAACTATCACATATTGTATAGCTACTGAAGAAAATGGCGAAGATAAAGTTCATCAACATGTTGGCAGAGAACCAAG
TGGTATTACTTTTAATGCTATAGCATTAAACAAGTATGACCTACCTCATAATCCAATGATAAACTCCGGCGCTATCATGA
TGTGCTCACTAATAAAACCGGAGTGGAATCTTGCTGATAGATTTGAATATATTACTAACGTTTGGCAAGATCTAGCAGGT
GGCGAACCTATCGGCTTTGATAACGCTGTATATCACTCCGAAAAAGAGACCGCAGATAGAAATTATGCTCTAGCTCATTT
TATGAAAGAAGTAGGTGCTTTTCCAGAGGGCACAAATATCCACACTGCTCTAGATTTCTATTTCCAAACTTGCTCTATTC
AAGTTAACGCAAAAAAAATGGCAAAAATTATGGCTTCCATAGCTAATGGCGGAGTATGCCCTTTTACTAGTAAAAAAATA
TTTTCACCAACAACGATTCGGAATTGCTTATCAATGATGTACTCGTGTGGGATGTATGATTTTTCAGGTGAATATGCGTT
CTCTGTTGGATTACCTGCAAAATCAGGGGTGTCAGGAGCTCTAGCTATAGCTATTCCAAATGTTGGTGGTTTTGCAATTT
TTTCTCCTCGACTTGACCCTAATCATAACTCCGTAAGAGGTGTTGAATTTAGTAAAAGGCTAATAGAGAAGTTTAGTTTC
CATAACTATGATCATATAACTCATTGTGACAAAATAAATCCCGTTGAGAATAGAATGGTTGTCGAATCAAATTTAACATT
TGAACTAATTTGGGCAGCAAGTGCCGGTGACTTATCAGAGATTAAAAGAGCCGTTGCCTTAGGTGTTGATATTAACAAAG
GTGATTATGATAAAAGAACAGCTCTTCACCTAGCCGCTGCTGAAGGTCATGAAGATATTGTTAAATACCTTATCCGCAAA
GGAGCGGATATTAATGCTATAGACAGATGGGGTAAAAAGCCATTAGATGATGCTATAATGAATAATAATATTTCTATAAT
TGAGCTGTTAGACAGAACTTAA

Upstream 100 bases:

>100_bases
CTAATGCTGCTATAAACTAACTATATTGTCTATATATCAAATCTTTGTTTTTTCGGTAAAATAACTCAATATTATTTTTT
ATAAAACCATATTTCTTTAA

Downstream 100 bases:

>100_bases
ATTAGCCTATGATCAATTTACTATTCATATACTTAGCGTATATCTTAGCTATTGTTTCGCTTTTATCTTTATGGATGATA
AAGTTTAGAATATTTGGATA

Product: glutaminase/ankyrin repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKTIMIKTTSSSGEDYYKNIFSAICDKDGFMTKTDILDILVESGISNDDPRITKLIAKLNKFCDIDKIDFDTFQEITFEN
IGLIEKAINKGFIIPNFKDFKKEIEAIYNETKKNETGRNANYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQST
AKTITYCIATEENGEDKVHQHVGREPSGITFNAIALNKYDLPHNPMINSGAIMMCSLIKPEWNLADRFEYITNVWQDLAG
GEPIGFDNAVYHSEKETADRNYALAHFMKEVGAFPEGTNIHTALDFYFQTCSIQVNAKKMAKIMASIANGGVCPFTSKKI
FSPTTIRNCLSMMYSCGMYDFSGEYAFSVGLPAKSGVSGALAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKFSF
HNYDHITHCDKINPVENRMVVESNLTFELIWAASAGDLSEIKRAVALGVDINKGDYDKRTALHLAAAEGHEDIVKYLIRK
GADINAIDRWGKKPLDDAIMNNNISIIELLDRT

Sequences:

>Translated_513_residues
MKTIMIKTTSSSGEDYYKNIFSAICDKDGFMTKTDILDILVESGISNDDPRITKLIAKLNKFCDIDKIDFDTFQEITFEN
IGLIEKAINKGFIIPNFKDFKKEIEAIYNETKKNETGRNANYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQST
AKTITYCIATEENGEDKVHQHVGREPSGITFNAIALNKYDLPHNPMINSGAIMMCSLIKPEWNLADRFEYITNVWQDLAG
GEPIGFDNAVYHSEKETADRNYALAHFMKEVGAFPEGTNIHTALDFYFQTCSIQVNAKKMAKIMASIANGGVCPFTSKKI
FSPTTIRNCLSMMYSCGMYDFSGEYAFSVGLPAKSGVSGALAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKFSF
HNYDHITHCDKINPVENRMVVESNLTFELIWAASAGDLSEIKRAVALGVDINKGDYDKRTALHLAAAEGHEDIVKYLIRK
GADINAIDRWGKKPLDDAIMNNNISIIELLDRT
>Mature_513_residues
MKTIMIKTTSSSGEDYYKNIFSAICDKDGFMTKTDILDILVESGISNDDPRITKLIAKLNKFCDIDKIDFDTFQEITFEN
IGLIEKAINKGFIIPNFKDFKKEIEAIYNETKKNETGRNANYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQST
AKTITYCIATEENGEDKVHQHVGREPSGITFNAIALNKYDLPHNPMINSGAIMMCSLIKPEWNLADRFEYITNVWQDLAG
GEPIGFDNAVYHSEKETADRNYALAHFMKEVGAFPEGTNIHTALDFYFQTCSIQVNAKKMAKIMASIANGGVCPFTSKKI
FSPTTIRNCLSMMYSCGMYDFSGEYAFSVGLPAKSGVSGALAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKFSF
HNYDHITHCDKINPVENRMVVESNLTFELIWAASAGDLSEIKRAVALGVDINKGDYDKRTALHLAAAEGHEDIVKYLIRK
GADINAIDRWGKKPLDDAIMNNNISIIELLDRT

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI20336214, Length=479, Percent_Identity=42.7974947807933, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI156104878, Length=478, Percent_Identity=42.4686192468619, Blast_Score=422, Evalue=1e-118,
Organism=Escherichia coli, GI1787804, Length=289, Percent_Identity=32.8719723183391, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786693, Length=304, Percent_Identity=34.2105263157895, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17532727, Length=479, Percent_Identity=44.8851774530271, Blast_Score=440, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI193204073, Length=498, Percent_Identity=42.7710843373494, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI193204075, Length=500, Percent_Identity=42.6, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17507019, Length=484, Percent_Identity=43.801652892562, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24653156, Length=515, Percent_Identity=43.3009708737864, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI281363239, Length=515, Percent_Identity=43.3009708737864, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI116008307, Length=515, Percent_Identity=43.3009708737864, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24653164, Length=515, Percent_Identity=43.3009708737864, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24653158, Length=515, Percent_Identity=43.3009708737864, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI281363241, Length=515, Percent_Identity=43.3009708737864, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24653162, Length=515, Percent_Identity=43.3009708737864, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24653166, Length=515, Percent_Identity=43.3009708737864, Blast_Score=446, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 57212; Mature: 57212

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIMIKTTSSSGEDYYKNIFSAICDKDGFMTKTDILDILVESGISNDDPRITKLIAKLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KFCDIDKIDFDTFQEITFENIGLIEKAINKGFIIPNFKDFKKEIEAIYNETKKNETGRNA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHCCCCCCCC
NYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQSTAKTITYCIATEENGEDKVHQ
CCCCHHHHCCCCEEEEEEEECCCEEEEECCHHCHHHHHHHHCEEEEEEEECCCCHHHHHH
HVGREPSGITFNAIALNKYDLPHNPMINSGAIMMCSLIKPEWNLADRFEYITNVWQDLAG
HHCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
GEPIGFDNAVYHSEKETADRNYALAHFMKEVGAFPEGTNIHTALDFYFQTCSIQVNAKKM
CCCCCCCCHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEEEEEECHHHH
AKIMASIANGGVCPFTSKKIFSPTTIRNCLSMMYSCGMYDFSGEYAFSVGLPAKSGVSGA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCE
LAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKFSFHNYDHITHCDKINPVENRMV
EEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
VESNLTFELIWAASAGDLSEIKRAVALGVDINKGDYDKRTALHLAAAEGHEDIVKYLIRK
EECCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHC
GADINAIDRWGKKPLDDAIMNNNISIIELLDRT
CCCCCHHHHCCCCCCHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MKTIMIKTTSSSGEDYYKNIFSAICDKDGFMTKTDILDILVESGISNDDPRITKLIAKLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KFCDIDKIDFDTFQEITFENIGLIEKAINKGFIIPNFKDFKKEIEAIYNETKKNETGRNA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHCCCCCCCC
NYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQSTAKTITYCIATEENGEDKVHQ
CCCCHHHHCCCCEEEEEEEECCCEEEEECCHHCHHHHHHHHCEEEEEEEECCCCHHHHHH
HVGREPSGITFNAIALNKYDLPHNPMINSGAIMMCSLIKPEWNLADRFEYITNVWQDLAG
HHCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
GEPIGFDNAVYHSEKETADRNYALAHFMKEVGAFPEGTNIHTALDFYFQTCSIQVNAKKM
CCCCCCCCHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEEEEEECHHHH
AKIMASIANGGVCPFTSKKIFSPTTIRNCLSMMYSCGMYDFSGEYAFSVGLPAKSGVSGA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCE
LAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKFSFHNYDHITHCDKINPVENRMV
EEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
VESNLTFELIWAASAGDLSEIKRAVALGVDINKGDYDKRTALHLAAAEGHEDIVKYLIRK
EECCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHC
GADINAIDRWGKKPLDDAIMNNNISIIELLDRT
CCCCCHHHHCCCCCCHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA