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The map label for this gene is aroE [H]

Identifier: 134302665

GI number: 134302665

Start: 1739220

End: 1739993

Strand: Reverse

Name: aroE [H]

Synonym: FTW_1853

Alternate gene names: 134302665

Gene position: 1739993-1739220 (Counterclockwise)

Preceding gene: 134302681

Following gene: 134302664

Centisome position: 91.65

GC content: 34.88

Gene sequence:

>774_bases
ATGAAAGATTTGTATCATGTGATTGGCTTTCCGGTGAAGCATAGCTTGTCGCCAGCTATTCAAATGAGATTAGCACAGCA
ATATAATCAAGATATGCTTTTTACTGCTATAGAAGTTGCACCACAAGATTTAGAGGCAAAAATCCAAGAATTTAAGACTA
ATCCTCAAGTTAAGGGCTTAAGTGTTACTGTGCCACATAAAGAGAGAGTTTATGCCTTAGTAGATGATGCTGATACTACT
GCTAAAGCTGTTCAGGCAGCTAGCAATGTTATATTCACAGCTGAGCGTAAAATGATTGCTTTGAACTATGATGGACTTGG
CATAGTCAATGACATCAAAAATAATTATAAGATTGATTTTGCTGGTAAAAAAGTGCTTGTGGTTGGTGCTGGAGGTGCAG
CAAAAGCGGTCGTTGCAGCAGTCCTTAAAGAATCACCATTATCTCTTAGTATTACAAATAGAACACTAGCCAAAGCCAAA
GCTATTGAAGAGCTTTTTAAAGTTGATACTAAGATTAAAATTATCGATTTTGATAATATTAGTGATTCTTTTGATATAGT
TATTAATTCAACATCATCAAGTATTGATGGTAAGTTACTTCCTTTAAAAGATAGTAATTTCAATAAAAATGCTTTTGCCT
ATGATCTAATGTATGCTGATGGTGGTACTATTTTTACAAAATGGTGTCAAGCTCATAATATTGCTGCGGCAGATGGTAAA
GGGATGCTTAAAGAGCTAAGTATCGCTGTGTTTAAATATTGGCGTGGATTGTGA

Upstream 100 bases:

>100_bases
ATAGCTCTATAATATTTATTTTTTCTTTTGTATTCAAGTCAAGCTAATCATTGTTAGTATGTTATAATCTTAAGATAAAC
TCTTTAAAACGTTTTTATCT

Downstream 100 bases:

>100_bases
TTAAGAATAAGGATTATGCTAAAATATTGTATACCAAATCATTATTAGCATAGTTGCTAGGCTAGTTTGAACAAAAAAAT
ATTATTTCTTGGAGTTGGCG

Product: putative shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKDLYHVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALVDDADTT
AKAVQAASNVIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTKIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAHNIAAADGK
GMLKELSIAVFKYWRGL

Sequences:

>Translated_257_residues
MKDLYHVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALVDDADTT
AKAVQAASNVIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTKIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAHNIAAADGK
GMLKELSIAVFKYWRGL
>Mature_257_residues
MKDLYHVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALVDDADTT
AKAVQAASNVIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTKIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAHNIAAADGK
GMLKELSIAVFKYWRGL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=259, Percent_Identity=30.8880308880309, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=25.8181818181818, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28164; Mature: 28164

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLYHVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGL
CCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
SVTVPHKERVYALVDDADTTAKAVQAASNVIFTAERKMIALNYDGLGIVNDIKNNYKIDF
EEECCCCCEEEEEEECCCHHHHHHHHHCCEEEEECCEEEEEECCCCEEHECCCCCEEEEE
AGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAKAIEELFKVDTKIKIIDFDNI
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
SDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAHNIAAADGK
CCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCEEHHHHHCCEECCCCC
GMLKELSIAVFKYWRGL
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDLYHVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGL
CCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
SVTVPHKERVYALVDDADTTAKAVQAASNVIFTAERKMIALNYDGLGIVNDIKNNYKIDF
EEECCCCCEEEEEEECCCHHHHHHHHHCCEEEEECCEEEEEECCCCEEHECCCCCEEEEE
AGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAKAIEELFKVDTKIKIIDFDNI
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
SDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAHNIAAADGK
CCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCEEHHHHHCCEECCCCC
GMLKELSIAVFKYWRGL
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA