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The map label for this gene is ipk [H]

Identifier: 134302647

GI number: 134302647

Start: 1720378

End: 1721205

Strand: Direct

Name: ipk [H]

Synonym: FTW_1830

Alternate gene names: 134302647

Gene position: 1720378-1721205 (Clockwise)

Preceding gene: 134302646

Following gene: 134302648

Centisome position: 90.62

GC content: 31.16

Gene sequence:

>828_bases
ATGGCAAATATAAAAGCTAAAAAATACTATAGTTATGCAAAGATAAATCTATTTTTGCATATATTAAACAAACGTACAGA
TGGTTACCATAATTTACAGACTTGGTTTACCTTTTTGGACTTAAAAGATCAACTAACTTTTAGTTTTAATAATTCACGAG
AAATTAATATTTCGAGTAATATTAGTATTGCTGCAAAACAAGATAATTTAGTATATAAGGCTATCAAAAAATTTCAGCAA
AGCTATAGAGTGCAAGATATAGGTGTTGATATTGAAATTAAGAAAAATATTCCAATGGGAGCAGGACTTGGCGGTGGAAG
CTCAAATGCTGCTACTACACTTATAGCTTTACGTGATTATTATTTGCCGCAGTTGTCAAATGAGGAGATGATTCCATTAG
CGGCAAAACTTGGTGCCGATGTGTCGATATTTGTTTATGGTAAATCTGCGTGGGCAGAAGGTATAGGTGAGATATTATAC
CATAAGGATTTTAGTCCGCAGTATGCGCTATTGATTAAACCGGATATCCATATTAGTACAAAAGAGTTTTTTACAAGTGA
GGATTTAATTAAGTCATCGGTTCTAATATCTAAAGATTTAGGCTTTGATAAGAGCATTATGCATAACGATTTTGAGAATG
TTTTTTATGCAAAATATCCAGAGTTTAGTCAATATCTAAAAGAGTTAGATAGTGATTTTAGAATGACAGGTACAGGTTCT
TGTTTTTATTTACTCTCAGCAGATAAAAATAAACTTGAGCAACTTGCAAGAAAAATTAATAAACCTCTTGACAAATGGCT
AGTCAAAACATTAAACTATGTCTACTAA

Upstream 100 bases:

>100_bases
TTAGTTATAGTAATTATCAACTAGTTGATTCTAAATATCCCTTACCAACAAAGATTAGGATGTCTAGAGATAATCTAACT
CTAAAAATCGTTATAAAATC

Downstream 100 bases:

>100_bases
CTTAAGGTTAGTCTCTGTTGGGCTATCGCCAAGCGGTAAGGCAACGGGTTTTGATCCCGTCATTCCCAGGTTCGAATCCT
GGTAGCCCAGCCATCAAAAC

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSNISIAAKQDNLVYKAIKKFQQ
SYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDYYLPQLSNEEMIPLAAKLGADVSIFVYGKSAWAEGIGEILY
HKDFSPQYALLIKPDIHISTKEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGS
CFYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY

Sequences:

>Translated_275_residues
MANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSNISIAAKQDNLVYKAIKKFQQ
SYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDYYLPQLSNEEMIPLAAKLGADVSIFVYGKSAWAEGIGEILY
HKDFSPQYALLIKPDIHISTKEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGS
CFYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY
>Mature_274_residues
ANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSNISIAAKQDNLVYKAIKKFQQS
YRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDYYLPQLSNEEMIPLAAKLGADVSIFVYGKSAWAEGIGEILYH
KDFSPQYALLIKPDIHISTKEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGSC
FYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=267, Percent_Identity=35.5805243445693, Blast_Score=137, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31465; Mature: 31334

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSN
CCCCCCHHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHEECCCEEEEEECCCEEEEECCC
ISIAAKQDNLVYKAIKKFQQSYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDY
EEEEECCCCHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCCCCCHHHEEEEHHHH
YLPQLSNEEMIPLAAKLGADVSIFVYGKSAWAEGIGEILYHKDFSPQYALLIKPDIHIST
HCCCCCCCCCCCHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCEECH
KEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGS
HHHHCHHHHHHHHHEEECCCCCCHHHHHCCHHHCEEECCCHHHHHHHHHCCCCEEECCCC
CFYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY
EEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSN
CCCCCHHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHEECCCEEEEEECCCEEEEECCC
ISIAAKQDNLVYKAIKKFQQSYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDY
EEEEECCCCHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCCCCCHHHEEEEHHHH
YLPQLSNEEMIPLAAKLGADVSIFVYGKSAWAEGIGEILYHKDFSPQYALLIKPDIHIST
HCCCCCCCCCCCHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCCEECH
KEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGS
HHHHCHHHHHHHHHEEECCCCCCHHHHHCCHHHCEEECCCHHHHHHHHHCCCCEEECCCC
CFYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY
EEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA