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The map label for this gene is cyoB [H]

Identifier: 134302624

GI number: 134302624

Start: 1693021

End: 1695051

Strand: Reverse

Name: cyoB [H]

Synonym: FTW_1804

Alternate gene names: 134302624

Gene position: 1695051-1693021 (Counterclockwise)

Preceding gene: 134302625

Following gene: 134302623

Centisome position: 89.28

GC content: 37.47

Gene sequence:

>2031_bases
ATGCTAGAAGCATTAATTGGAAAATTAAATAATCCGCATTTAGTGTTTCCATACCTATATGAACCAGTAAGTCAACAGTT
AATTATATTAACAATGTTTATTGGAATCGTAGTCGCAGGTGTGGCATTACTAGGCGGTATTACATATTTTAGAAAATGGG
GTTACTTATGGAATGAGTGGTTCACTACTATTGACCATAAGAAAATAGGTACTATGTATACTATCGTAGCATTAGTGATG
ATGTTCCGTGGTTTTGTTGATGCTGCGATGATGAGAACACAGCAAGCGTTAGCATCTGGAGATAGTACAGGATATCTAAT
CCCTGAGCATTTTGATCAAATCTTCTCTGCTCATGGTGTAATTATGATTTTCTTTGTGGCGATGCCTCTTATATTTGCAC
TAATGAACTGGGTGATTCCTTTACAGATTGGTGCTAGAGACGTTGCGTTCCCTTATATGAACTCTTTGAGCTTTTGGTTG
TTCGTAGTCGGTGCAATGCTGATAAATATTTCACTATTGGTTGGAGATTTTGCGCACGCTGGTTGGTTAGCTTATCCGCC
ATTCTCAGAAACAACCTATAGCCCTACAGTAGGTACAGACTATTATATTTGGGGTCTACAAATATCTGGTATTGGTTCAC
TAATGACAGGGATTAACTTCTTTGTAACTATTATCAAAATGCGTTGCAAAGGTATGACGTTAATGAAGATGCCTATCTTT
ACATGGGCTTCATTATGTTCAGTTATCCTTGTGGTTGCTGCTTTTCCAGTTTTAACTGTGACTTTAGGGTTATTGACTTT
AGATAGATATTTCGGGACTCACTTCTTCACTGTTTCAGGTGGTGGAGACCAAATGATGTATGTCAACCTAATCTGGATTT
GGGGACATCCTGAAGTTTATATTCTTGTATTACCTTTATTCGGGGTATTCTCAGAAGTTGCGGCGACATTCTCTAAGAAG
CCACTTTTTGGATATACAACAATGGTTTGGGCAAGTATAGTTATTACTATCTTGTCGTTTACTGTATGGTTACACCATTT
CTTCACAATGGGTGCGAGTGCAAATGTTAATGCCTTCTTTGGAATTATGACAATGATTATTGCAATTCCTACGGGCGTTA
AGATCTTTAACTGGCTATTTACAATGTATAAAGGTCGTATTACATTTGCAACGCCGATGATGTGGCTGATTGGTTTTATG
ATAGTTTTCTCTGTTGGTGGAATGACAGGGGTATTATTATCTGTACCAGGCGTTGACTTCCAAATGCATAATAGTGTGTT
CTTAATTGCACATTTCCATAATGTTATTATTGGAGGCGTTGTATTTGGTGCCTTTTCTGGTCTTACTTTTTGGTTTCCAA
AAATATTTGGTTTCAAATTAAATGAGCGTTTAGGCAAGTATTCATTATGGTGCTGGTTTATTGGCTTCTTTGTAGCGTTT
ATGCCATTGTATATATTAGGTACTATGGGTATGACAAGAAGACTGTATCACTATGATGCTGCCACAGGATATCAACCACT
GCTTATAGTTGCTTGGGTTGGTGCAATGATTATTGGTTTAGGAATATTACTACAAATTATACAGATTTTTGTAAGTATTA
AGCAAAGAGACCAAAATCGTGTTGGCGCTGATGCTTGGGGTTATGGTCGCACATTAGAGTGGGGTATACCTTCTCCAGTG
CCTTTCTATAATTTCTCGCATGATCCAGTGGTTGAAAAGCGTGATGCATATTGGGGTCATAAGCAAAAGGGTCTAAATGT
AGATAATACTCCTGTAGGTAGTGCTAAGAAATATGAAGATATTCATATGCCAAAAAATACAGCTGTGGGAGTTATAATCG
GAGCATTCAGCTTTGTATTTGGATTCGCTGCAGTATGGCATATTTGGTGGCTTGCTATCGTCGGTGTTGTTGGTATCATT
GGTACTGTATTGTACAGATCATTTGATTATGATATCGATTACTATGTCAAGGCTGATCAAGTTAAAGAAGTTGAGAGTAG
ATATAATCAACAAGGAGAGTTACAAGTATGA

Upstream 100 bases:

>100_bases
ACTATAAGCCAGGAGACATGGCTTGTAATATGTCTGGTATGCACATGCATCATGATATGTAGTATTATTAATAAGTAGTA
GTTTTAAATAGGAGACAAAT

Downstream 100 bases:

>100_bases
GTACAGTAACTGCAGAACATAACCATCATCATGAACATCATTTTGATGGTTCAAAAAATGTTTTTGGTTTTTGGATATAT
ATTATGAGTGATTGTGTGCT

Product: cytochrome o ubiquinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MLEALIGKLNNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSLWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWGHKQKGLNVDNTPVGSAKKYEDIHMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV

Sequences:

>Translated_676_residues
MLEALIGKLNNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSLWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWGHKQKGLNVDNTPVGSAKKYEDIHMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV
>Mature_676_residues
MLEALIGKLNNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEWFTTIDHKKIGTMYTIVALVM
MFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGVIMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWL
FVVGAMLINISLLVGDFAHAGWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVYILVLPLFGVFSEVAATFSKK
PLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFFGIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFM
IVFSVGGMTGVLLSVPGVDFQMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSLWCWFIGFFVAF
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNRVGADAWGYGRTLEWGIPSPV
PFYNFSHDPVVEKRDAYWGHKQKGLNVDNTPVGSAKKYEDIHMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGII
GTVLYRSFDYDIDYYVKADQVKEVESRYNQQGELQV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=520, Percent_Identity=36.7307692307692, Blast_Score=316, Evalue=4e-86,
Organism=Escherichia coli, GI1786634, Length=648, Percent_Identity=64.1975308641975, Blast_Score=864, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=499, Percent_Identity=38.877755511022, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=41.6149068322981, Blast_Score=243, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=34.5238095238095, Blast_Score=133, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 76159; Mature: 76159

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEALIGKLNNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEW
CCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTTIDHKKIGTMYTIVALVMMFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
IMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWLFVVGAMLINISLLVGDFAHA
HHHHHHHHHHHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
CCEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEECCCCEE
ILVLPLFGVFSEVAATFSKKPLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFF
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFMIVFSVGGMTGVLLSVPGVDF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHEECCCCCE
QMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSLWCWFIGFFVAF
EECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGADAWGYGRTLEWGIPSPVPFYNFSHDPVVEKRDAYWGHKQKGLNVDNTPVGSAKKYED
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IHMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGIIGTVLYRSFDYDIDYYVKADQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VKEVESRYNQQGELQV
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLEALIGKLNNPHLVFPYLYEPVSQQLIILTMFIGIVVAGVALLGGITYFRKWGYLWNEW
CCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTTIDHKKIGTMYTIVALVMMFRGFVDAAMMRTQQALASGDSTGYLIPEHFDQIFSAHGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
IMIFFVAMPLIFALMNWVIPLQIGARDVAFPYMNSLSFWLFVVGAMLINISLLVGDFAHA
HHHHHHHHHHHHHHHHHHEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWLAYPPFSETTYSPTVGTDYYIWGLQISGIGSLMTGINFFVTIIKMRCKGMTLMKMPIF
CCEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
TWASLCSVILVVAAFPVLTVTLGLLTLDRYFGTHFFTVSGGGDQMMYVNLIWIWGHPEVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEECCCCEE
ILVLPLFGVFSEVAATFSKKPLFGYTTMVWASIVITILSFTVWLHHFFTMGASANVNAFF
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIMTMIIAIPTGVKIFNWLFTMYKGRITFATPMMWLIGFMIVFSVGGMTGVLLSVPGVDF
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHEECCCCCE
QMHNSVFLIAHFHNVIIGGVVFGAFSGLTFWFPKIFGFKLNERLGKYSLWCWFIGFFVAF
EECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
MPLYILGTMGMTRRLYHYDAATGYQPLLIVAWVGAMIIGLGILLQIIQIFVSIKQRDQNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGADAWGYGRTLEWGIPSPVPFYNFSHDPVVEKRDAYWGHKQKGLNVDNTPVGSAKKYED
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IHMPKNTAVGVIIGAFSFVFGFAAVWHIWWLAIVGVVGIIGTVLYRSFDYDIDYYVKADQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VKEVESRYNQQGELQV
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]