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The map label for this gene is pcp [H]

Identifier: 134302611

GI number: 134302611

Start: 1680556

End: 1681224

Strand: Reverse

Name: pcp [H]

Synonym: FTW_1789

Alternate gene names: 134302611

Gene position: 1681224-1680556 (Counterclockwise)

Preceding gene: 134302612

Following gene: 134302610

Centisome position: 88.56

GC content: 34.98

Gene sequence:

>669_bases
ATGAAAAAAATTTTATTATGCATATTTATGTTTGTGGCTTTTGTTGTTTCAGTAAATGCACAAACTATCCTTGTAACAGG
TTTTGCACCTTTTTGTGGTGAGAAGATAAACCCATCTTGGCAAGCGGTTAAGCAACTCCCTGATAGTATTGATGGAGCCA
AAATTATCAAAAAACAAATTCCTGTTTCATTTAAGGGTTCTGTTAATGATTTAGACAAATTGATAGAGAAATATAACCCT
GATGTGATTATTGCGGTTGGTGAAGCTGGCGGTCGAGCAGCAGTATCTATCGAAAGAGTAGCGATAAATGTTGATGATGC
TAGAATTGCAGATAATGATAACTATCAACCTAAGAATATCAAAATCTCAGCAAATGGCGAAAATGCTTATTTCTCTAAGC
TACCAATTTATAAAATCCAAGCTGCAATACAAGCACAAGGCATTCCAGCTTATATATCTGATAGCGCTGGGACATATGTT
TGTAACCATGTGATGTATCATCTATTAGAAGTACTCAGCAAAAAGTATCCTAATAAAATAGCTGGATTTATACATATCCC
GTATGCGCCACAGCAAGTTGTGAATAAATCAGATATGCCTAGTATGAGTACTGATCAAGCTACACAAGCATTAAAAATAG
CGATACAAACATCGATAACTAAGCAATAG

Upstream 100 bases:

>100_bases
TAATAATTATCATGAGCTGCTAAATTTAATTAAAAGTACAACTAAAGTTACTAAAACAAAATCTAGTAAGTTAGTTAAAG
GTTTATACGAGTAGGTGATT

Downstream 100 bases:

>100_bases
GATTTGTATGGAGAAAGACTGGAAATATTATTTAGGTATATTACTGTTTATTTTATCATTTGTGCCATATATTTTAGTTT
TTGTGATTATGCCTTTTTTA

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKKILLCIFMFVAFVVSVNAQTILVTGFAPFCGEKINPSWQAVKQLPDSIDGAKIIKKQIPVSFKGSVNDLDKLIEKYNP
DVIIAVGEAGGRAAVSIERVAINVDDARIADNDNYQPKNIKISANGENAYFSKLPIYKIQAAIQAQGIPAYISDSAGTYV
CNHVMYHLLEVLSKKYPNKIAGFIHIPYAPQQVVNKSDMPSMSTDQATQALKIAIQTSITKQ

Sequences:

>Translated_222_residues
MKKILLCIFMFVAFVVSVNAQTILVTGFAPFCGEKINPSWQAVKQLPDSIDGAKIIKKQIPVSFKGSVNDLDKLIEKYNP
DVIIAVGEAGGRAAVSIERVAINVDDARIADNDNYQPKNIKISANGENAYFSKLPIYKIQAAIQAQGIPAYISDSAGTYV
CNHVMYHLLEVLSKKYPNKIAGFIHIPYAPQQVVNKSDMPSMSTDQATQALKIAIQTSITKQ
>Mature_222_residues
MKKILLCIFMFVAFVVSVNAQTILVTGFAPFCGEKINPSWQAVKQLPDSIDGAKIIKKQIPVSFKGSVNDLDKLIEKYNP
DVIIAVGEAGGRAAVSIERVAINVDDARIADNDNYQPKNIKISANGENAYFSKLPIYKIQAAIQAQGIPAYISDSAGTYV
CNHVMYHLLEVLSKKYPNKIAGFIHIPYAPQQVVNKSDMPSMSTDQATQALKIAIQTSITKQ

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 24289; Mature: 24289

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLCIFMFVAFVVSVNAQTILVTGFAPFCGEKINPSWQAVKQLPDSIDGAKIIKKQI
CHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHC
PVSFKGSVNDLDKLIEKYNPDVIIAVGEAGGRAAVSIERVAINVDDARIADNDNYQPKNI
CEEECCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCEECCCCCCCCCEE
KISANGENAYFSKLPIYKIQAAIQAQGIPAYISDSAGTYVCNHVMYHLLEVLSKKYPNKI
EEEECCCCCEECCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHH
AGFIHIPYAPQQVVNKSDMPSMSTDQATQALKIAIQTSITKQ
EEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKILLCIFMFVAFVVSVNAQTILVTGFAPFCGEKINPSWQAVKQLPDSIDGAKIIKKQI
CHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHC
PVSFKGSVNDLDKLIEKYNPDVIIAVGEAGGRAAVSIERVAINVDDARIADNDNYQPKNI
CEEECCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCEECCCCCCCCCEE
KISANGENAYFSKLPIYKIQAAIQAQGIPAYISDSAGTYVCNHVMYHLLEVLSKKYPNKI
EEEECCCCCEECCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHH
AGFIHIPYAPQQVVNKSDMPSMSTDQATQALKIAIQTSITKQ
EEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA