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The map label for this gene is xasA [C]

Identifier: 134302551

GI number: 134302551

Start: 1629586

End: 1630935

Strand: Direct

Name: xasA [C]

Synonym: FTW_1719

Alternate gene names: 134302551

Gene position: 1629586-1630935 (Clockwise)

Preceding gene: 134302550

Following gene: 134302555

Centisome position: 85.84

GC content: 32.22

Gene sequence:

>1350_bases
ATGGATATAAATTCTAATCAAGATCAAGTTCTAGGTTTTAAAGATGTTACAATCATGGCTGTAACAGCTAATTTTGGTAT
TCGCTGGATACCTGTAGCAGCTTGTTTGGGAGCTTCAGCAATATTCTTTTGGATACTTGGGGCGGTGATGTTTTTCTTGC
CTTTGGTCATAATTGCAGTTCAGTTATCAAGAAAACATCCTGATGAAGGTGGTATTTATTCATGGACTGTTAGAGCCTTA
GGACAAAAGGCGGGTTTTATGGTGGCATGGTTATACTGGGTGAATACGATTTTTTATTATCCAGCTGTACTTATCTTTTT
AGCTACTAACTTTGCATATTTTATAGGTCGACCTGATTTGGTTGATAATCATTATTATATAACGATAGTTGTTTTAGTAG
CTTTTTGGTTGGTTACGGTGATTAGTTTTTATGGTCTAAAAGCTAATAAATATCTAGTTGATATAGGAGGTGTTCTAGGC
TCTTTTTTACCTGCTATAGCGATTATTGTTCTGGGTTTTATAGCATATTTAATTGTAGGAAAAAGTGCTACAGATTTTTC
TTTGGCTAATATGATTCCGCACGATAATATTTGGCATAACTTATCAACACTAACTATTATCATGTTTGCAATGGCAGGTA
TAGAAATCATCCCAACTTTTGCTAATTCAGTCAAAGATGCTAAGAAAAATCTATATTATGGTCTAATGTTTTCTGCATTC
ATTTTATTGGGTTTGTATATATTAGGAACAATTGCTTTGAATCTTGTTGCATCACCTGACACGATAAATAGCTCTTCAGG
ACTTATGGAAGCATTTGAAATAATTGATCATAGATTTGGTTGGGAATGGTTCCCAAGGTTAATGGCTTTTTTACTTACTT
TTGCAGAGCTGGCTGCTGTGAGTATTTGGCTTTTAGCGCCTGTTGTAATGTTTTTTAAATGTACACCTAGAGGAATATTA
CCAGAGTGGTTGCATAAAACTAATAAGTATGATTCTCCTAAAAATGCTTTAGTATTTATGGGGATATTAGTAACGGTTAT
AGTGTTACTAACTAATTTCTTACCATCAGTAAATTTGATGTATCAAGCTTTAATACTTATGGCTACAGTACTTTATTTTA
TCCCTTACTTATATTTAGTGGTTGCTTATATTAAGCTTATGGATAGTACTTATAAGTATTTATTAGGGTTTTTAGTATTT
ATATCGACATCACTTGGAATTATATTTAGTTTTCAACCATCTAGTGACTTAACAGGTGGATATGATATTTTCATATATGA
ATTTGAATTAATCCTTGGACCTGTAATTTTTATATTTATCGGTTGGTTGTTATATAAATTCAAGCGATAA

Upstream 100 bases:

>100_bases
TCATATATTTATAATATACTCTTTGTAAATATTTTCTTATATATCTATTTTTTATTACATATAATAACGCTTAGCATATT
TTAAGATAAAGGTTTAGTAT

Downstream 100 bases:

>100_bases
TTATTCAGAAATATAGTTCCACTAATATCTATTAAGGAAATTATCTAGAATATTTGTTGGTAGTATCCTTTTTAACGATG
CCATAATCCAAGTTGCTTTG

Product: amino acid transporter

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MDINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWVNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDIGGVLG
SFLPAIAIIVLGFIAYLIVGKSATDFSLANMIPHDNIWHNLSTLTIIMFAMAGIEIIPTFANSVKDAKKNLYYGLMFSAF
ILLGLYILGTIALNLVASPDTINSSSGLMEAFEIIDHRFGWEWFPRLMAFLLTFAELAAVSIWLLAPVVMFFKCTPRGIL
PEWLHKTNKYDSPKNALVFMGILVTVIVLLTNFLPSVNLMYQALILMATVLYFIPYLYLVVAYIKLMDSTYKYLLGFLVF
ISTSLGIIFSFQPSSDLTGGYDIFIYEFELILGPVIFIFIGWLLYKFKR

Sequences:

>Translated_449_residues
MDINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWVNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDIGGVLG
SFLPAIAIIVLGFIAYLIVGKSATDFSLANMIPHDNIWHNLSTLTIIMFAMAGIEIIPTFANSVKDAKKNLYYGLMFSAF
ILLGLYILGTIALNLVASPDTINSSSGLMEAFEIIDHRFGWEWFPRLMAFLLTFAELAAVSIWLLAPVVMFFKCTPRGIL
PEWLHKTNKYDSPKNALVFMGILVTVIVLLTNFLPSVNLMYQALILMATVLYFIPYLYLVVAYIKLMDSTYKYLLGFLVF
ISTSLGIIFSFQPSSDLTGGYDIFIYEFELILGPVIFIFIGWLLYKFKR
>Mature_449_residues
MDINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAVQLSRKHPDEGGIYSWTVRAL
GQKAGFMVAWLYWVNTIFYYPAVLIFLATNFAYFIGRPDLVDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDIGGVLG
SFLPAIAIIVLGFIAYLIVGKSATDFSLANMIPHDNIWHNLSTLTIIMFAMAGIEIIPTFANSVKDAKKNLYYGLMFSAF
ILLGLYILGTIALNLVASPDTINSSSGLMEAFEIIDHRFGWEWFPRLMAFLLTFAELAAVSIWLLAPVVMFFKCTPRGIL
PEWLHKTNKYDSPKNALVFMGILVTVIVLLTNFLPSVNLMYQALILMATVLYFIPYLYLVVAYIKLMDSTYKYLLGFLVF
ISTSLGIIFSFQPSSDLTGGYDIFIYEFELILGPVIFIFIGWLLYKFKR

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=436, Percent_Identity=23.6238532110092, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082380, Length=401, Percent_Identity=24.6882793017456, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081798, Length=409, Percent_Identity=23.2273838630807, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994921, Length=396, Percent_Identity=23.989898989899, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI2367353, Length=391, Percent_Identity=22.2506393861893, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50595; Mature: 50595

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAV
CCCCCCCCCEECEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSRKHPDEGGIYSWTVRALGQKAGFMVAWLYWVNTIFYYPAVLIFLATNFAYFIGRPDL
HHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDIGGVLGSFLPAIAIIVLGFIAYLIVG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
KSATDFSLANMIPHDNIWHNLSTLTIIMFAMAGIEIIPTFANSVKDAKKNLYYGLMFSAF
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLGLYILGTIALNLVASPDTINSSSGLMEAFEIIDHRFGWEWFPRLMAFLLTFAELAAV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SIWLLAPVVMFFKCTPRGILPEWLHKTNKYDSPKNALVFMGILVTVIVLLTNFLPSVNLM
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
YQALILMATVLYFIPYLYLVVAYIKLMDSTYKYLLGFLVFISTSLGIIFSFQPSSDLTGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
YDIFIYEFELILGPVIFIFIGWLLYKFKR
EEEEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDINSNQDQVLGFKDVTIMAVTANFGIRWIPVAACLGASAIFFWILGAVMFFLPLVIIAV
CCCCCCCCCEECEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLSRKHPDEGGIYSWTVRALGQKAGFMVAWLYWVNTIFYYPAVLIFLATNFAYFIGRPDL
HHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDNHYYITIVVLVAFWLVTVISFYGLKANKYLVDIGGVLGSFLPAIAIIVLGFIAYLIVG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
KSATDFSLANMIPHDNIWHNLSTLTIIMFAMAGIEIIPTFANSVKDAKKNLYYGLMFSAF
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLGLYILGTIALNLVASPDTINSSSGLMEAFEIIDHRFGWEWFPRLMAFLLTFAELAAV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SIWLLAPVVMFFKCTPRGILPEWLHKTNKYDSPKNALVFMGILVTVIVLLTNFLPSVNLM
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
YQALILMATVLYFIPYLYLVVAYIKLMDSTYKYLLGFLVFISTSLGIIFSFQPSSDLTGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
YDIFIYEFELILGPVIFIFIGWLLYKFKR
EEEEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]