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The map label for this gene is speH [H]

Identifier: 134302488

GI number: 134302488

Start: 1547111

End: 1547599

Strand: Reverse

Name: speH [H]

Synonym: FTW_1644

Alternate gene names: 134302488

Gene position: 1547599-1547111 (Counterclockwise)

Preceding gene: 134302490

Following gene: 134302487

Centisome position: 81.52

GC content: 34.97

Gene sequence:

>489_bases
ATGATCATTCAAAATACTACAGCTATCCTAGATAGCAACTTAAAAAATAAAGAAGTGGGTTCAGGTAAATGGCCTGAGCA
TAACAATCAAATCTGTGATAACCTTCATCAAGATCACTTTATTCAAGAAAGTGTAAGGTACGCGGGAAATCATTTAATAG
TCGACTTTTGGGGTGCTAGTAAATTAGATTGCCTTGAGACTATGGAAGTAGCAATGCGTGAAGCAGTTGAGAAAGCTAAA
GCAACATTGTTACACATTCACCTTCACCATTTTACACCTAATGGCGGTATTTCTGGAGTTGCTGTCTTAGCAGAATCACA
TATAAGTGTTCACACTTGGCCTGAGTATGGTTTTGCAGCTTTTGATATATTTATGTGTGGAGATTCTAAACCTAATAAAG
CAATAGAAGTTTTAGAAAGTTATTTTAAGCCTAAAACAAATAATGTAAGTAAGTTTAGAAGAGGTGAAGTAGTCGAGGTA
GTAAATTAA

Upstream 100 bases:

>100_bases
ATAACATAAAACAAAGAGGATTTATGGCTTTAATTTAATATAGCACTTAGGCTTTTTGACTAGAAAAAAGTCTAAGTGCG
CCCCAAATAGGAGATGAAAA

Downstream 100 bases:

>100_bases
TGATAGCTAATATTAATAATAAAAAAATATTTCATGAAACTTTGTACCATAGCTATCATCAAAGTATAGCAATTTCTGAA
ATATTGTATGAACATAAAAC

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MIIQNTTAILDSNLKNKEVGSGKWPEHNNQICDNLHQDHFIQESVRYAGNHLIVDFWGASKLDCLETMEVAMREAVEKAK
ATLLHIHLHHFTPNGGISGVAVLAESHISVHTWPEYGFAAFDIFMCGDSKPNKAIEVLESYFKPKTNNVSKFRRGEVVEV
VN

Sequences:

>Translated_162_residues
MIIQNTTAILDSNLKNKEVGSGKWPEHNNQICDNLHQDHFIQESVRYAGNHLIVDFWGASKLDCLETMEVAMREAVEKAK
ATLLHIHLHHFTPNGGISGVAVLAESHISVHTWPEYGFAAFDIFMCGDSKPNKAIEVLESYFKPKTNNVSKFRRGEVVEV
VN
>Mature_162_residues
MIIQNTTAILDSNLKNKEVGSGKWPEHNNQICDNLHQDHFIQESVRYAGNHLIVDFWGASKLDCLETMEVAMREAVEKAK
ATLLHIHLHHFTPNGGISGVAVLAESHISVHTWPEYGFAAFDIFMCGDSKPNKAIEVLESYFKPKTNNVSKFRRGEVVEV
VN

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 18215; Mature: 18215

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIQNTTAILDSNLKNKEVGSGKWPEHNNQICDNLHQDHFIQESVRYAGNHLIVDFWGAS
CEECCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
KLDCLETMEVAMREAVEKAKATLLHIHLHHFTPNGGISGVAVLAESHISVHTWPEYGFAA
CHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCEEEEECCCCEEEECCCCCCEE
FDIFMCGDSKPNKAIEVLESYFKPKTNNVSKFRRGEVVEVVN
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCCCEEEECC
>Mature Secondary Structure
MIIQNTTAILDSNLKNKEVGSGKWPEHNNQICDNLHQDHFIQESVRYAGNHLIVDFWGAS
CEECCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
KLDCLETMEVAMREAVEKAKATLLHIHLHHFTPNGGISGVAVLAESHISVHTWPEYGFAA
CHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCEEEEECCCCEEEECCCCCCEE
FDIFMCGDSKPNKAIEVLESYFKPKTNNVSKFRRGEVVEVVN
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA