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The map label for this gene is kdsA [H]

Identifier: 134302406

GI number: 134302406

Start: 1447511

End: 1448359

Strand: Reverse

Name: kdsA [H]

Synonym: FTW_1542

Alternate gene names: 134302406

Gene position: 1448359-1447511 (Counterclockwise)

Preceding gene: 134302407

Following gene: 134302405

Centisome position: 76.29

GC content: 36.28

Gene sequence:

>849_bases
GTGTATTTAAATAAAAATCTTATGAAAATTGCTAATTTTGAAGTAGGAAATGGTAAGCCATTTTTCTTAATGTCTGGTCC
TTGTGTCATTGAATCTGAGCAAATGGCGATGGATACTGCTGGATATCTTGCTGAGGTAACTAAGGATCTTGGAATAAATT
TTGTTTATAAGTCATCTTTTGATAAAGCAAATCGCTCATCTATAAATAGCTTTAGAGGGCTAGGTGTAGATAAAGGTCTT
GAAATTTTGGCTAAGGTCAAAAAGACTTATAATGTGCCTGTCGTTACAGATGTCCATGAAGATACACCCTTTGCTGAGGT
TGCTGAAGTTGTTGATGTATTACAAACTCCTGCTTTTTTATGCCGTCAAACAAACTTTATTCTTGAGGTCTGTAAGCAAG
GAAAACCTGTAAATATCAAAAAGGGTCAGTTTCTCGCACCTTGGGATATGCAGCATGTAGTAACAAAAGCTAAATCTACA
GGCAATGAGCAGATTATGGTTTGCGAAAGAGGTGTAAGCTTTGGTTATAATAATCTAGTTTCAGATATGCGTTCACTTGA
GATTATGAAAGCTACAGGATGTCCGGTAGTATTTGATGCTACTCACTCAGTGCAATTACCAGGAGGACAAGGTAGTTCTT
CTGGTGGGCAGAGAGAGTTTGTACCAGTTTTATCAAAAGCAGCTATGGCTGTTGGTATAGATGGACTTTTTATGGAAACT
CATCCAAATCCTGATGAGGCAAAAAGTGATGGACCTAATTCGTTCCCAATGTATAAAATAAAAGAATTTTTAAGTTTGCT
AAAAGAGCTTGATCATTTAGTAAAAAGTCAACCAAAGACAGAACTATAG

Upstream 100 bases:

>100_bases
CTACAAAGATGATGTCGAAGGTGCATACTTTGTAATTAGAAATCCAAATGCGAAAACTACTTGTGGCTGTGGTTCATCTT
TTTCTGTATAATTATCACAA

Downstream 100 bases:

>100_bases
GGCATAAATAATGGCTGGTAAAGGCGATGTTTTTATAATAGGTATAGTTGGTGGTTCTGGTTCTGGTAAAACATTATTTT
CAAATGCTATCATCAAAAAA

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MYLNKNLMKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGL
EILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKST
GNEQIMVCERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMET
HPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL

Sequences:

>Translated_282_residues
MYLNKNLMKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGL
EILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKST
GNEQIMVCERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMET
HPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
>Mature_282_residues
MYLNKNLMKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSFDKANRSSINSFRGLGVDKGL
EILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFLCRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKST
GNEQIMVCERGVSFGYNNLVSDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMET
HPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=275, Percent_Identity=45.8181818181818, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30983; Mature: 30983

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLNKNLMKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSF
CCCCCCHHHHHCEECCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCC
DKANRSSINSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCHHHH
CRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLV
HHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
SDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMET
HHHHHHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEC
HPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYLNKNLMKIANFEVGNGKPFFLMSGPCVIESEQMAMDTAGYLAEVTKDLGINFVYKSSF
CCCCCCHHHHHCEECCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCC
DKANRSSINSFRGLGVDKGLEILAKVKKTYNVPVVTDVHEDTPFAEVAEVVDVLQTPAFL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCHHHH
CRQTNFILEVCKQGKPVNIKKGQFLAPWDMQHVVTKAKSTGNEQIMVCERGVSFGYNNLV
HHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
SDMRSLEIMKATGCPVVFDATHSVQLPGGQGSSSGGQREFVPVLSKAAMAVGIDGLFMET
HHHHHHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEC
HPNPDEAKSDGPNSFPMYKIKEFLSLLKELDHLVKSQPKTEL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA