Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 134302357

GI number: 134302357

Start: 1383617

End: 1385239

Strand: Reverse

Name: pgi [H]

Synonym: FTW_1481

Alternate gene names: 134302357

Gene position: 1385239-1383617 (Counterclockwise)

Preceding gene: 134302358

Following gene: 134302356

Centisome position: 72.97

GC content: 32.78

Gene sequence:

>1623_bases
ATGCTATTTTGTGATGATTCTAAAAAATATTTGAAAGAGCAAAATATAAACTTAAAAAATGAATTTGACAAAGATGATAA
AAGAGTTGAGAAGTTCTCTCTAAAACATCAAAACATATATTTTGATTATTCAAAAAATCTTATTAATGATTATATTTTAA
AGTCTCTTTTAGAGTCTGCAGAAAAATCTAGTCTTAAAGATAAAATTAAACAGATGTTTAATGGTGCTAAGATTAATTCT
ACTGAACACAGAGCTGTTTTACATACGGCGTTGCGCGATTTGTCTAGTACGCCATTAATTGTTGATGGGCAAGATATTCG
TCAAGAAGTAACAAAAGAAAAGCAGCGTGTAAAAGAGCTTGTTGAAAAAGTGGTATCTGGTCGATGGCGTGGATTCTCTG
GTAAAAAGATTACTGATATTGTAAATATTGGTATTGGTGGCTCAGATCTTGGACCTAAAATGGTGGTTAGAGCATTACAA
CCTTATCATTGTACAGATTTAAAAGTTCACTTTGTTTCAAATGTTGATGCTGACTCGCTATTACAAGCACTACATGTTGT
TGATCCTGAAACTACTTTGTTTATCATAGCTTCAAAATCATTCTCAACTGAAGAGACTTTGTTAAATTCTATTTCAGCTA
GAGAGTGGTTGTTAGATCATTATGAGGATGAAAAAGCTGTAGCTAACCATTTTGTTGCAATATCGAGTAAGTTAGACAAA
GTTAAAGAATTTGGTATAGATTTAGAGCATTGTTATAAAATGTGGGATTGGGTTGGCGGTCGCTATTCATTATGGTCATC
AATTGGGATGTCGATAGCTTTTGCTATAGGTTATGATAATTTTGAGAAATTACTAGCTGGAGCGTACTCAGTTGATAAAC
ATTTTAAAGAAACTGAATTTAGCAAAAATATTCCTGTGATTATGGCATTGCTGGCAAGTTATTATAGCTGTACGTATAAT
AGTCAGTCACAAGCGTTACTTCCTTATGACGAGAGACTTTGTTATTTTGTTGATTATCTTCAGCAAGCAGATATGGAAAG
TAATGGTAAATCAGTAAATATTGCTGGTGAAACTGTCAATTATCAAACTGGAGTTGTACTTTGGGGTGGTGTTGGTACTA
ATGGTCAGCATGCTTTTCATCAACTTTTACATCAAGGTAATATTTTTATACCCGTTGATTTTATTGCTATTGCAACTAGT
CATCATAATTATGATAACCATCAGCAGGCTTTACTTGCTAATTGTTTTGCACAGTCACAAGCACTAATGTTTGGACAATC
ATATGATATGGTTTATAATGAGCTGTTAAAATCTGGTTTGAATGAAACTCAAGCAAAAGAGCTTGCGGCTCATAAGGTTA
TACCAGGTAATAGACCAAGTACAACAATTTTACTTGATGAGCTAAGTCCATATAGTCTTGGTGTCTTGATTGCTTTGTAT
GAGCATAAAATATTTGTTCAGGGTGTGTTATGGGACATCAATAGCTATGATCAGTGGGGTGTTGAGCTTGGCAAAAAACT
TGGTAAAAATATATTAAAAGCTATGAATGATGATTCATCTGATGAGTATCAAAATTTAGATGATTCAACTAGACAGTTAA
TAGCGAAGGTAAAAAATAAATAA

Upstream 100 bases:

>100_bases
GGTGCAAGAAATTATGCTACAGAGGATAAGGTTGAGATATCTTATTCAAGTGGAGATATTTTGTTGTTTATATCACATAG
AAAATATAAGGATAGATTAG

Downstream 100 bases:

>100_bases
ATGATTATAAGTAAAAAGAAAGGCTTCTCTTTAGTTCAGACTATGGTTGTTATTGCTATCATGACAATACTTATGATGGC
GGCAATTAGCTCGTTTACTT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINS
TEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQ
PYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDK
VKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYN
SQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATS
HHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALY
EHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK

Sequences:

>Translated_540_residues
MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINS
TEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQ
PYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDK
VKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYN
SQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATS
HHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALY
EHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
>Mature_540_residues
MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINS
TEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQ
PYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDK
VKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYN
SQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATS
HHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALY
EHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=531, Percent_Identity=48.5875706214689, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI296080693, Length=531, Percent_Identity=45.0094161958569, Blast_Score=484, Evalue=1e-136,
Organism=Escherichia coli, GI1790457, Length=532, Percent_Identity=49.6240601503759, Blast_Score=545, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71996708, Length=533, Percent_Identity=49.155722326454, Blast_Score=528, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71996703, Length=533, Percent_Identity=49.155722326454, Blast_Score=528, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6319673, Length=533, Percent_Identity=47.4671669793621, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24651916, Length=534, Percent_Identity=51.87265917603, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI24651914, Length=534, Percent_Identity=51.87265917603, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI17737445, Length=534, Percent_Identity=51.87265917603, Blast_Score=548, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61181; Mature: 61181

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESA
CEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHH
EKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKEL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHH
VEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSL
HHHHHCCCCCCCCCCEEHHEEEECCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCHHHH
LQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDK
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEF
HHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHC
SKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVN
CCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
YQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQ
EECCEEEECCCCCCCHHHHHHHHHCCCEEEEEHHEEEEECCCCCCHHHHHHHHHHHHHHH
ALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALY
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHH
EHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
HHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESA
CEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHH
EKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKEL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHH
VEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSL
HHHHHCCCCCCCCCCEEHHEEEECCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCHHHH
LQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDK
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEF
HHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHC
SKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVN
CCCCHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
YQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQ
EECCEEEECCCCCCCHHHHHHHHHCCCEEEEEHHEEEEECCCCCCHHHHHHHHHHHHHHH
ALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALY
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHH
EHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
HHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA