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The map label for this gene is tolC [H]

Identifier: 134302303

GI number: 134302303

Start: 1311802

End: 1313184

Strand: Reverse

Name: tolC [H]

Synonym: FTW_1401

Alternate gene names: 134302303

Gene position: 1313184-1311802 (Counterclockwise)

Preceding gene: 134302304

Following gene: 134302302

Centisome position: 69.17

GC content: 32.97

Gene sequence:

>1383_bases
TTGAAAGTAGTGCGTAGATATTTATTAATATCCTTGGGTATATTTGCTTATTGTGCTAGTAGTATAGCTAATCCTGTAGC
TGACTATACTAGTATGATAAAGCAATCAATAAATAATTCACCACAGTATAAGTTTATTGGCTTTCAGCTTAACTCAAGGC
AAATGAGCCCAGCGATACAGCTAGGTAGATTATTACCAAGTATAGATATCGGTGGTTCAATTACAGCAACAAATATTTTA
GATAAAAGAACAATAGCCGATGGTGATATTGCTGGTGGACGTTTTGATTCGATTCAAGGTTTGGTAACTCTAACCCAACC
ACTATATGATTATGGTGCGTATAAGGATTTACAATCAGCTGAGGAAACAGCACAGTTTGCCCAACAGGATTATAGAACAA
ATTATCAGCAATTTTTATATGATGTGAGTTACGCATATTTTAACCTTGCTAAAGCAATAAAAAACGTTCAGTATAATTCA
TATAACTTAAAATCAAACAAACAAAGCTTAAATGAGCTTGAAAGTAAATTCAAAGCTGGTACTGCAGACGTTGCAGATTA
TGAAACTGTCAAGGCTAACTATTATATAGCCGAGGCTGATTATGCAGCTGCAGAAAGAGAAGAAAAAGTAGCCCGTGCAG
AATTACGTAAATTTACTAATAATGATGATGATGTACTCTTATATAATAATGATTTTAAGATTAAACAACCATCACTTAAT
ACAGAAGAAGGTTGGGAAGAGCTAACAATGCGTAGCAGCCCATCATATTTAGGTTCAATGCATACTAAAGAAAGTAAGTA
TTATGATTATCAATCAGCGACAAGCTCATTTATGCCTAAAGTTAACTTTGAAGTTAAGTATTCGCCGGGTTTTAATGATG
TTAGTTCACTTGGTAACCCAGTATTTGATAATTCTTTACCATCTAAGGGTACGATAAATGCATTTTATTTTGGAATTAAT
TTAACATGGAATATTTTTGCCGGCGTTACAGATTATGCTCAGTTGAAAAAAGCAGCTTATGATTATCAATCATCTGAGTT
TACTATGATTCAAACTGGGAGGGTAGCGCAGAATGATGCGATGTATGCCTTTAGATTTGTCCAACTTAAGAAAAAAGAAA
TAGAATCGCTACGTAAATCTGTTGCAGCAGCAAAGATTGCTTATGAGAAATATAAAGAACGCTACGACCAAGGTACAACA
ACGATTACTCAGTATTTCATTCTTTTAAACCAATATTATCAATTTCTTATTCAACTTAACAATACTGAATTTGATTATAT
TATGGGATTTTTAAGTTTATACAAAACAGCTGGTATTTTAACAGCTAAAACAGTGCAAGATTTTAATAATTGGTTACTAT
TAGGTCAAGACGTGGAGCTATAA

Upstream 100 bases:

>100_bases
GATATGGCTCAAGGTGGTGGTAATAACTCTGCGAATATAGATCAAGCTTTATCTCAAGTAGAAAAATTTATTTTAAATAA
TATAAAAGAGTAGTGGTGGC

Downstream 100 bases:

>100_bases
AGATGTATATATCAACCAAATTAGAGTGTTTTACACAACATAAACAAAATGATTCTTTGCCAATTTTTGTGATTAATAAG
GATAATTTTGCAAATTGGCT

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKVVRRYLLISLGIFAYCASSIANPVADYTSMIKQSINNSPQYKFIGFQLNSRQMSPAIQLGRLLPSIDIGGSITATNIL
DKRTIADGDIAGGRFDSIQGLVTLTQPLYDYGAYKDLQSAEETAQFAQQDYRTNYQQFLYDVSYAYFNLAKAIKNVQYNS
YNLKSNKQSLNELESKFKAGTADVADYETVKANYYIAEADYAAAEREEKVARAELRKFTNNDDDVLLYNNDFKIKQPSLN
TEEGWEELTMRSSPSYLGSMHTKESKYYDYQSATSSFMPKVNFEVKYSPGFNDVSSLGNPVFDNSLPSKGTINAFYFGIN
LTWNIFAGVTDYAQLKKAAYDYQSSEFTMIQTGRVAQNDAMYAFRFVQLKKKEIESLRKSVAAAKIAYEKYKERYDQGTT
TITQYFILLNQYYQFLIQLNNTEFDYIMGFLSLYKTAGILTAKTVQDFNNWLLLGQDVEL

Sequences:

>Translated_460_residues
MKVVRRYLLISLGIFAYCASSIANPVADYTSMIKQSINNSPQYKFIGFQLNSRQMSPAIQLGRLLPSIDIGGSITATNIL
DKRTIADGDIAGGRFDSIQGLVTLTQPLYDYGAYKDLQSAEETAQFAQQDYRTNYQQFLYDVSYAYFNLAKAIKNVQYNS
YNLKSNKQSLNELESKFKAGTADVADYETVKANYYIAEADYAAAEREEKVARAELRKFTNNDDDVLLYNNDFKIKQPSLN
TEEGWEELTMRSSPSYLGSMHTKESKYYDYQSATSSFMPKVNFEVKYSPGFNDVSSLGNPVFDNSLPSKGTINAFYFGIN
LTWNIFAGVTDYAQLKKAAYDYQSSEFTMIQTGRVAQNDAMYAFRFVQLKKKEIESLRKSVAAAKIAYEKYKERYDQGTT
TITQYFILLNQYYQFLIQLNNTEFDYIMGFLSLYKTAGILTAKTVQDFNNWLLLGQDVEL
>Mature_460_residues
MKVVRRYLLISLGIFAYCASSIANPVADYTSMIKQSINNSPQYKFIGFQLNSRQMSPAIQLGRLLPSIDIGGSITATNIL
DKRTIADGDIAGGRFDSIQGLVTLTQPLYDYGAYKDLQSAEETAQFAQQDYRTNYQQFLYDVSYAYFNLAKAIKNVQYNS
YNLKSNKQSLNELESKFKAGTADVADYETVKANYYIAEADYAAAEREEKVARAELRKFTNNDDDVLLYNNDFKIKQPSLN
TEEGWEELTMRSSPSYLGSMHTKESKYYDYQSATSSFMPKVNFEVKYSPGFNDVSSLGNPVFDNSLPSKGTINAFYFGIN
LTWNIFAGVTDYAQLKKAAYDYQSSEFTMIQTGRVAQNDAMYAFRFVQLKKKEIESLRKSVAAAKIAYEKYKERYDQGTT
TITQYFILLNQYYQFLIQLNNTEFDYIMGFLSLYKTAGILTAKTVQDFNNWLLLGQDVEL

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=409, Percent_Identity=20.7823960880196, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52427; Mature: 52427

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVRRYLLISLGIFAYCASSIANPVADYTSMIKQSINNSPQYKFIGFQLNSRQMSPAIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHH
LGRLLPSIDIGGSITATNILDKRTIADGDIAGGRFDSIQGLVTLTQPLYDYGAYKDLQSA
HHHHCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
EETAQFAQQDYRTNYQQFLYDVSYAYFNLAKAIKNVQYNSYNLKSNKQSLNELESKFKAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
TADVADYETVKANYYIAEADYAAAEREEKVARAELRKFTNNDDDVLLYNNDFKIKQPSLN
CCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCC
TEEGWEELTMRSSPSYLGSMHTKESKYYDYQSATSSFMPKVNFEVKYSPGFNDVSSLGNP
CHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHCCCC
VFDNSLPSKGTINAFYFGINLTWNIFAGVTDYAQLKKAAYDYQSSEFTMIQTGRVAQNDA
CCCCCCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
MYAFRFVQLKKKEIESLRKSVAAAKIAYEKYKERYDQGTTTITQYFILLNQYYQFLIQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NTEFDYIMGFLSLYKTAGILTAKTVQDFNNWLLLGQDVEL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MKVVRRYLLISLGIFAYCASSIANPVADYTSMIKQSINNSPQYKFIGFQLNSRQMSPAIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHH
LGRLLPSIDIGGSITATNILDKRTIADGDIAGGRFDSIQGLVTLTQPLYDYGAYKDLQSA
HHHHCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
EETAQFAQQDYRTNYQQFLYDVSYAYFNLAKAIKNVQYNSYNLKSNKQSLNELESKFKAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
TADVADYETVKANYYIAEADYAAAEREEKVARAELRKFTNNDDDVLLYNNDFKIKQPSLN
CCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCC
TEEGWEELTMRSSPSYLGSMHTKESKYYDYQSATSSFMPKVNFEVKYSPGFNDVSSLGNP
CHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHCCCC
VFDNSLPSKGTINAFYFGINLTWNIFAGVTDYAQLKKAAYDYQSSEFTMIQTGRVAQNDA
CCCCCCCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
MYAFRFVQLKKKEIESLRKSVAAAKIAYEKYKERYDQGTTTITQYFILLNQYYQFLIQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NTEFDYIMGFLSLYKTAGILTAKTVQDFNNWLLLGQDVEL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]