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The map label for this gene is htpX [H]

Identifier: 134302242

GI number: 134302242

Start: 1248139

End: 1249212

Strand: Direct

Name: htpX [H]

Synonym: FTW_1322

Alternate gene names: 134302242

Gene position: 1248139-1249212 (Clockwise)

Preceding gene: 134302241

Following gene: 134302243

Centisome position: 65.74

GC content: 32.87

Gene sequence:

>1074_bases
ATGTCAGCTGCTGATAATTTAGAATATGGCTCTGTAAATTGGCGCGAAGTTGTACGTAAGAACACTTATCGCACTTATTT
TGTAATCGCAACATTCCTTATAGTATTTTTCTTATTAGGAATCTTTATTGATACAATATGGCGCTATAGTGAATTTGTAA
ATGCACACTACAGTTATTATAATAGTCAGCCACAAATATCAATAGGGAAAGTATTCTTGTTGTTATTGACATTTCAAATA
CCTCCTTATGCGACTATGATAATCTCTACTGTAGCAGTAATTTGGGTATTTGTTACATTTAGCATGTACGATAAGATCAT
GCTCTCTGGCACAGAATATCAAGAAATTACTGCAGATAATCAAGATCCACTAGCTCGCCGTGTTTATAATGTCGTTGAAG
AGATGAAAGTTGCTGCTGGTATGCGATATATACCTAAAGTATTTCTTATCGATGCTAATTATATGAATGCTTTTGCATCA
GGATATTCTGAAAAATCCGCAATGGTGGCTATCACTACAAAACTTGCAAACGCACTTAATCGTGATGAACTACAAGCAGT
TATGGCACATGAGCTAACTCATATTAGAAACCAAGATATCAAGTTAAATTTATTTACTATGGTTTTATCAAATATGATGC
TTATTATTATGGACTTTTTATTTTATTCAGCACTTTTCTCAAGCAATAGTAATAACAATAATAACAACCGTAATAATAAT
GCTGCTGCATTTTTTATCATCATTATGATCTTAAGATATGTGTTACAAATATTTACGATATTTATGATGTTATTTTTAAG
TCGTACGCGAGAATATATGGCTGATGCTGGTGCTGTTGAGCTAATGCGTACTAACATGCCGATGGCAAATGCATTAATAA
AAATTGCAAACGACAGTAAATCTGTAGAAGCTCAATACAGCTACAAGCATAATAAAAATGAAAATTTACGTCGAGCATCG
TATATTTTTGATCCACTTAGTGCTGGAATCAGCAGTGGTGATATGTCTGATTTATTTTCCACTCACCCTTCTATCGAAAA
AAGACTTGCTTCAATTGGTGTAAAACTTAGATAA

Upstream 100 bases:

>100_bases
GGTTAGCATATTTAAAAAGCTTAATGAAGACTTTGTTTACTGGAATATTTCTGAAGAGAAAAAACAACAACTAGAAGATT
CAAGAGTGGAACTATAAAAA

Downstream 100 bases:

>100_bases
TCCAGCCAATTTATCCATCAATTAAAAACCTTTTAATACTTATTTTAGCCTACTATTAGTAAAGAAATAGGCTATAATTA
AATGGCTAAGAAATAGGTTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSAADNLEYGSVNWREVVRKNTYRTYFVIATFLIVFFLLGIFIDTIWRYSEFVNAHYSYYNSQPQISIGKVFLLLLTFQI
PPYATMIISTVAVIWVFVTFSMYDKIMLSGTEYQEITADNQDPLARRVYNVVEEMKVAAGMRYIPKVFLIDANYMNAFAS
GYSEKSAMVAITTKLANALNRDELQAVMAHELTHIRNQDIKLNLFTMVLSNMMLIIMDFLFYSALFSSNSNNNNNNRNNN
AAAFFIIIMILRYVLQIFTIFMMLFLSRTREYMADAGAVELMRTNMPMANALIKIANDSKSVEAQYSYKHNKNENLRRAS
YIFDPLSAGISSGDMSDLFSTHPSIEKRLASIGVKLR

Sequences:

>Translated_357_residues
MSAADNLEYGSVNWREVVRKNTYRTYFVIATFLIVFFLLGIFIDTIWRYSEFVNAHYSYYNSQPQISIGKVFLLLLTFQI
PPYATMIISTVAVIWVFVTFSMYDKIMLSGTEYQEITADNQDPLARRVYNVVEEMKVAAGMRYIPKVFLIDANYMNAFAS
GYSEKSAMVAITTKLANALNRDELQAVMAHELTHIRNQDIKLNLFTMVLSNMMLIIMDFLFYSALFSSNSNNNNNNRNNN
AAAFFIIIMILRYVLQIFTIFMMLFLSRTREYMADAGAVELMRTNMPMANALIKIANDSKSVEAQYSYKHNKNENLRRAS
YIFDPLSAGISSGDMSDLFSTHPSIEKRLASIGVKLR
>Mature_356_residues
SAADNLEYGSVNWREVVRKNTYRTYFVIATFLIVFFLLGIFIDTIWRYSEFVNAHYSYYNSQPQISIGKVFLLLLTFQIP
PYATMIISTVAVIWVFVTFSMYDKIMLSGTEYQEITADNQDPLARRVYNVVEEMKVAAGMRYIPKVFLIDANYMNAFASG
YSEKSAMVAITTKLANALNRDELQAVMAHELTHIRNQDIKLNLFTMVLSNMMLIIMDFLFYSALFSSNSNNNNNNRNNNA
AAFFIIIMILRYVLQIFTIFMMLFLSRTREYMADAGAVELMRTNMPMANALIKIANDSKSVEAQYSYKHNKNENLRRASY
IFDPLSAGISSGDMSDLFSTHPSIEKRLASIGVKLR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=241, Percent_Identity=26.5560165975104, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 40957; Mature: 40826

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADNLEYGSVNWREVVRKNTYRTYFVIATFLIVFFLLGIFIDTIWRYSEFVNAHYSYY
CCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSQPQISIGKVFLLLLTFQIPPYATMIISTVAVIWVFVTFSMYDKIMLSGTEYQEITADN
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
QDPLARRVYNVVEEMKVAAGMRYIPKVFLIDANYMNAFASGYSEKSAMVAITTKLANALN
CCHHHHHHHHHHHHHHHHHCHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHC
RDELQAVMAHELTHIRNQDIKLNLFTMVLSNMMLIIMDFLFYSALFSSNSNNNNNNRNNN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAAFFIIIMILRYVLQIFTIFMMLFLSRTREYMADAGAVELMRTNMPMANALIKIANDSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCC
SVEAQYSYKHNKNENLRRASYIFDPLSAGISSGDMSDLFSTHPSIEKRLASIGVKLR
CCEEHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAADNLEYGSVNWREVVRKNTYRTYFVIATFLIVFFLLGIFIDTIWRYSEFVNAHYSYY
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSQPQISIGKVFLLLLTFQIPPYATMIISTVAVIWVFVTFSMYDKIMLSGTEYQEITADN
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
QDPLARRVYNVVEEMKVAAGMRYIPKVFLIDANYMNAFASGYSEKSAMVAITTKLANALN
CCHHHHHHHHHHHHHHHHHCHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHC
RDELQAVMAHELTHIRNQDIKLNLFTMVLSNMMLIIMDFLFYSALFSSNSNNNNNNRNNN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AAAFFIIIMILRYVLQIFTIFMMLFLSRTREYMADAGAVELMRTNMPMANALIKIANDSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCCC
SVEAQYSYKHNKNENLRRASYIFDPLSAGISSGDMSDLFSTHPSIEKRLASIGVKLR
CCEEHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]