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The map label for this gene is era [H]

Identifier: 134302151

GI number: 134302151

Start: 1138842

End: 1139735

Strand: Reverse

Name: era [H]

Synonym: FTW_1207

Alternate gene names: 134302151

Gene position: 1139735-1138842 (Counterclockwise)

Preceding gene: 134302152

Following gene: 134302150

Centisome position: 60.03

GC content: 32.89

Gene sequence:

>894_bases
ATGAAAAAATGTGGCTACATTTCAATTATAGGTAGACCTAATGTCGGTAAATCTACTTTGTTAAATAATATACTTAAATA
TAAAGTAAGTATCACTTCACGTAAACCTCAGACAACTAGACATCAAATTACAGGTATTAAGACGCTTGGTGATACTCAGT
TTATCTATGTTGATACTCCAGGTATACATATCAAAGAACCTAAAGCTATAAATAAATTTATGAATAAAGCAGCAACAACA
ATGTTTAAAGATGTTGATGTAATTTTATTTGTAGTTGAGATGGGTAAATGGACAGAGCTAGAGGATAATATTGTTGAGAA
ATTAAAGCACTCAGAAATTCCGATATTTTTAGTTGTTAACAAGGTTGATAAGAAAAAATCATTAGAAGCAGCGATGTTTA
TCGAATCTATTAAAGAAAAGCTAAGTTTTTATGATGTGATTTATGTATCAGCTAAGCAGGGACACAACATCAATGAGCTA
GAATCAAGAATTGAAAAGCTTTTGCCAGAGTCTGAATATTTTTTCTATGAAGAAGATCAAATTACCGATAGAAGCATTAA
ATTCATGGTAGCTGAAATTATCCGTGAGAAGATTATGCGTACTATAGGTAGCGAGGTGCCATACCAAATAGCTGTAGAGA
TAGACAGCTATAAGGTTGATCAAGAAAAAAATATTGTCTATATCTATGCTAGTATACTTGTTGAGAGAGATAGTCAAAAA
GGTATTGTGATAGGTGCTAAAGGAGCCAAACTCAAAAAGATTGGTACAGACTCACGTATAGATATCGAAAGGTTAGTTGG
TATGCAGGTTAACCTTAAAACTCATGTCAAAGTCAAAAGTGGCTGGTCAGATGATGATCGCGCGTTGAAGTCACTTGGCT
ATGATCTAATCTAA

Upstream 100 bases:

>100_bases
CTTACTATGTAAGCTATAAATTTATTAAATACAAAAAATATTTTCGACACTAAATTAGATAGCTGCTACAATCTATAATT
ATTTCTCTTATGATTTTTTT

Downstream 100 bases:

>100_bases
GTATAGTTTTATCTATGCAGCGACTTGAGCTTAAAGTATCGCCAAGATACCGCAATATTATTTATGCAAGTTTAGTGTTT
ATTAGTAGTTTTGTGATTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKCGYISIIGRPNVGKSTLLNNILKYKVSITSRKPQTTRHQITGIKTLGDTQFIYVDTPGIHIKEPKAINKFMNKAATT
MFKDVDVILFVVEMGKWTELEDNIVEKLKHSEIPIFLVVNKVDKKKSLEAAMFIESIKEKLSFYDVIYVSAKQGHNINEL
ESRIEKLLPESEYFFYEEDQITDRSIKFMVAEIIREKIMRTIGSEVPYQIAVEIDSYKVDQEKNIVYIYASILVERDSQK
GIVIGAKGAKLKKIGTDSRIDIERLVGMQVNLKTHVKVKSGWSDDDRALKSLGYDLI

Sequences:

>Translated_297_residues
MKKCGYISIIGRPNVGKSTLLNNILKYKVSITSRKPQTTRHQITGIKTLGDTQFIYVDTPGIHIKEPKAINKFMNKAATT
MFKDVDVILFVVEMGKWTELEDNIVEKLKHSEIPIFLVVNKVDKKKSLEAAMFIESIKEKLSFYDVIYVSAKQGHNINEL
ESRIEKLLPESEYFFYEEDQITDRSIKFMVAEIIREKIMRTIGSEVPYQIAVEIDSYKVDQEKNIVYIYASILVERDSQK
GIVIGAKGAKLKKIGTDSRIDIERLVGMQVNLKTHVKVKSGWSDDDRALKSLGYDLI
>Mature_297_residues
MKKCGYISIIGRPNVGKSTLLNNILKYKVSITSRKPQTTRHQITGIKTLGDTQFIYVDTPGIHIKEPKAINKFMNKAATT
MFKDVDVILFVVEMGKWTELEDNIVEKLKHSEIPIFLVVNKVDKKKSLEAAMFIESIKEKLSFYDVIYVSAKQGHNINEL
ESRIEKLLPESEYFFYEEDQITDRSIKFMVAEIIREKIMRTIGSEVPYQIAVEIDSYKVDQEKNIVYIYASILVERDSQK
GIVIGAKGAKLKKIGTDSRIDIERLVGMQVNLKTHVKVKSGWSDDDRALKSLGYDLI

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=329, Percent_Identity=26.7477203647416, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=49.3150684931507, Blast_Score=293, Evalue=8e-81,
Organism=Escherichia coli, GI87082120, Length=174, Percent_Identity=28.1609195402299, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646434, Length=304, Percent_Identity=29.6052631578947, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33974; Mature: 33974

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50823 KH_TYPE_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCGYISIIGRPNVGKSTLLNNILKYKVSITSRKPQTTRHQITGIKTLGDTQFIYVDTP
CCCCCEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHEEEEEECCEEEEEEECC
GIHIKEPKAINKFMNKAATTMFKDVDVILFVVEMGKWTELEDNIVEKLKHSEIPIFLVVN
CCEEECCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
KVDKKKSLEAAMFIESIKEKLSFYDVIYVSAKQGHNINELESRIEKLLPESEYFFYEEDQ
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCC
ITDRSIKFMVAEIIREKIMRTIGSEVPYQIAVEIDSYKVDQEKNIVYIYASILVERDSQK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECEEECCCCCEEEEEEEEEEECCCCC
GIVIGAKGAKLKKIGTDSRIDIERLVGMQVNLKTHVKVKSGWSDDDRALKSLGYDLI
CEEEECCCCEEEECCCCCCCCHHHHCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKCGYISIIGRPNVGKSTLLNNILKYKVSITSRKPQTTRHQITGIKTLGDTQFIYVDTP
CCCCCEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHEEEEEECCEEEEEEECC
GIHIKEPKAINKFMNKAATTMFKDVDVILFVVEMGKWTELEDNIVEKLKHSEIPIFLVVN
CCEEECCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
KVDKKKSLEAAMFIESIKEKLSFYDVIYVSAKQGHNINELESRIEKLLPESEYFFYEEDQ
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCC
ITDRSIKFMVAEIIREKIMRTIGSEVPYQIAVEIDSYKVDQEKNIVYIYASILVERDSQK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECEEECCCCCEEEEEEEEEEECCCCC
GIVIGAKGAKLKKIGTDSRIDIERLVGMQVNLKTHVKVKSGWSDDDRALKSLGYDLI
CEEEECCCCEEEECCCCCCCCHHHHCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]