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The map label for this gene is pilC [H]

Identifier: 134302125

GI number: 134302125

Start: 1107962

End: 1109191

Strand: Direct

Name: pilC [H]

Synonym: FTW_1167

Alternate gene names: 134302125

Gene position: 1107962-1109191 (Clockwise)

Preceding gene: 134302124

Following gene: 134302128

Centisome position: 58.36

GC content: 34.15

Gene sequence:

>1230_bases
ATGCTATTTGGCAAAAAAGATAAAAATAAAAGAACTATTACATCATGGAATTATAAAGCTAAGCTAAAAAGTGGTAAAAA
GACTAAAGGTAGTATTGATGCTGACACCAAAGAGAAGGCAGAAATTCAATTAAGACAAAAGGGCTACTCTGATATCAAAG
TCAAAAAACAACCTAAAGATCTATTACCTAAGAAGATATCTTATCAAGATATTACCGAGATGACGCGCCAGCTAGCAATA
ATGACCAAAGCTGGTATTCCCATAATCAAATCATTTGAAGTATTTATTATGGGTATTTGTAAACATCCGCGCCTTAAAAT
ATTAGCTATTGAGATAAAGCAAGCTATCGAAGGGGGCGAGTCATTTTCAAAGGCTCTCAGAAACTTTCCTAAGATATTTG
ATAAATTATATGTTGGTCTTATTACTGCTGGTGAAGAATCAGGGAATCTTGATCTAATGCTTAATAAAATTGCTGATCAG
CGTGAAGCACTACAGAGTATCAAAAAGAAAGTAAAAAAAGCACTATCTTACCCAATTATAGTATGTATTATCGCTGCTGG
GGTTACAGGTATCCTATTAACATTTGCTGTGCCAGCTTTCTCAGCAATGTTTATAAATTCAGGAAAACCACTACCAGCAA
TCACACAATTAACTGTTGATGCATCTAACTTTATGCAAAATTCATGGTGGAAAATTATTCTGGCAATATTTATCACAATA
ACAGTTTATAAATCATTGAAATTTAGATTTCCTAAAATCCAAATTGCCCAAGATCATTTTATCTTAAAAGTACCAATAAT
TGGTGAAGTTGTATTTAAATCATCACTAGCAAGATTTGCTAGTACTTTAGAGATAACCGTCCAATCTGGTATGAGTCTGA
CACGTGCTCTAGATATGGTGTCTTTAGCAACGGGAAATGCAAAGTATGATCAAGCTGCTTTAGATATTAAAAAGAGTATT
AATGAAGGTGCCTCATTTAAAGAAGCAATCGTTGAAACTGGAAACTTCCCGTTTTTAGTTGAACAAATGATTGCTGTAGG
TGAGGAATCAGGTGCTCTAGAGACAATGCTAGGCAACCTAAATAGAGTATACCAAGAAGAAGTAGATACATTAGTAGGAA
GCTTAAGCTCAATGCTTGAACCTTTGATTATGATTGTCTTAGGTGGTGTTGTTGGTTTTCTCGTAGTTAGTATGTATATG
CCGATGTTTCAAATGGGTGATGCGATATAA

Upstream 100 bases:

>100_bases
AAGGAATCGCTACTGTCAGACAATCAGCTCTAGTCAGGGTTGCTGAAGATCTAACATCAATGGAAGAAGCATACCGCGTA
AGTTAAAGGGAATAAAAAAT

Downstream 100 bases:

>100_bases
TATACTTTTAAAAATTAGCGTCGAATTTATCCTTTTATGTTCAAGATGAATATTTTTTATACTAGAATTTCAATTATTTA
ATATCTGGCCAATACCAATT

Product: Type IV pili polytopic inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLFGKKDKNKRTITSWNYKAKLKSGKKTKGSIDADTKEKAEIQLRQKGYSDIKVKKQPKDLLPKKISYQDITEMTRQLAI
MTKAGIPIIKSFEVFIMGICKHPRLKILAIEIKQAIEGGESFSKALRNFPKIFDKLYVGLITAGEESGNLDLMLNKIADQ
REALQSIKKKVKKALSYPIIVCIIAAGVTGILLTFAVPAFSAMFINSGKPLPAITQLTVDASNFMQNSWWKIILAIFITI
TVYKSLKFRFPKIQIAQDHFILKVPIIGEVVFKSSLARFASTLEITVQSGMSLTRALDMVSLATGNAKYDQAALDIKKSI
NEGASFKEAIVETGNFPFLVEQMIAVGEESGALETMLGNLNRVYQEEVDTLVGSLSSMLEPLIMIVLGGVVGFLVVSMYM
PMFQMGDAI

Sequences:

>Translated_409_residues
MLFGKKDKNKRTITSWNYKAKLKSGKKTKGSIDADTKEKAEIQLRQKGYSDIKVKKQPKDLLPKKISYQDITEMTRQLAI
MTKAGIPIIKSFEVFIMGICKHPRLKILAIEIKQAIEGGESFSKALRNFPKIFDKLYVGLITAGEESGNLDLMLNKIADQ
REALQSIKKKVKKALSYPIIVCIIAAGVTGILLTFAVPAFSAMFINSGKPLPAITQLTVDASNFMQNSWWKIILAIFITI
TVYKSLKFRFPKIQIAQDHFILKVPIIGEVVFKSSLARFASTLEITVQSGMSLTRALDMVSLATGNAKYDQAALDIKKSI
NEGASFKEAIVETGNFPFLVEQMIAVGEESGALETMLGNLNRVYQEEVDTLVGSLSSMLEPLIMIVLGGVVGFLVVSMYM
PMFQMGDAI
>Mature_409_residues
MLFGKKDKNKRTITSWNYKAKLKSGKKTKGSIDADTKEKAEIQLRQKGYSDIKVKKQPKDLLPKKISYQDITEMTRQLAI
MTKAGIPIIKSFEVFIMGICKHPRLKILAIEIKQAIEGGESFSKALRNFPKIFDKLYVGLITAGEESGNLDLMLNKIADQ
REALQSIKKKVKKALSYPIIVCIIAAGVTGILLTFAVPAFSAMFINSGKPLPAITQLTVDASNFMQNSWWKIILAIFITI
TVYKSLKFRFPKIQIAQDHFILKVPIIGEVVFKSSLARFASTLEITVQSGMSLTRALDMVSLATGNAKYDQAALDIKKSI
NEGASFKEAIVETGNFPFLVEQMIAVGEESGALETMLGNLNRVYQEEVDTLVGSLSSMLEPLIMIVLGGVVGFLVVSMYM
PMFQMGDAI

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=409, Percent_Identity=29.3398533007335, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1786295, Length=396, Percent_Identity=28.5353535353535, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45270; Mature: 45270

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFGKKDKNKRTITSWNYKAKLKSGKKTKGSIDADTKEKAEIQLRQKGYSDIKVKKQPKD
CCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCHH
LLPKKISYQDITEMTRQLAIMTKAGIPIIKSFEVFIMGICKHPRLKILAIEIKQAIEGGE
HCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCH
SFSKALRNFPKIFDKLYVGLITAGEESGNLDLMLNKIADQREALQSIKKKVKKALSYPII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VCIIAAGVTGILLTFAVPAFSAMFINSGKPLPAITQLTVDASNFMQNSWWKIILAIFITI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECHHHHHHHHHHHHHHHHHHHH
TVYKSLKFRFPKIQIAQDHFILKVPIIGEVVFKSSLARFASTLEITVQSGMSLTRALDMV
HHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SLATGNAKYDQAALDIKKSINEGASFKEAIVETGNFPFLVEQMIAVGEESGALETMLGNL
HHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
NRVYQEEVDTLVGSLSSMLEPLIMIVLGGVVGFLVVSMYMPMFQMGDAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLFGKKDKNKRTITSWNYKAKLKSGKKTKGSIDADTKEKAEIQLRQKGYSDIKVKKQPKD
CCCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCHH
LLPKKISYQDITEMTRQLAIMTKAGIPIIKSFEVFIMGICKHPRLKILAIEIKQAIEGGE
HCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCH
SFSKALRNFPKIFDKLYVGLITAGEESGNLDLMLNKIADQREALQSIKKKVKKALSYPII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VCIIAAGVTGILLTFAVPAFSAMFINSGKPLPAITQLTVDASNFMQNSWWKIILAIFITI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECHHHHHHHHHHHHHHHHHHHH
TVYKSLKFRFPKIQIAQDHFILKVPIIGEVVFKSSLARFASTLEITVQSGMSLTRALDMV
HHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SLATGNAKYDQAALDIKKSINEGASFKEAIVETGNFPFLVEQMIAVGEESGALETMLGNL
HHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
NRVYQEEVDTLVGSLSSMLEPLIMIVLGGVVGFLVVSMYMPMFQMGDAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]