Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 134302101

GI number: 134302101

Start: 1081017

End: 1082294

Strand: Reverse

Name: aroA [H]

Synonym: FTW_1141

Alternate gene names: 134302101

Gene position: 1082294-1081017 (Counterclockwise)

Preceding gene: 134302102

Following gene: 134302100

Centisome position: 57.01

GC content: 36.78

Gene sequence:

>1278_bases
ATGAAAGATTTTATCCTTCAAATAAAATCACAGATAAAACAGCAAGTGTATTTAGATGGCTCAAAGAGTATCTCAAATAG
ATCACTGATAATCGCAGCGATGGCTCAAGGTCAAACAAAATTTGAGAATTTGCCTAATAGTGCTGATGTTTTAGCATGTA
TTGCAGCTCTAAAGGAGTTAGGTTGTCAGCTAGAACATAGCCGGGATTCAAAAACTTTAGTTATTCAAGGTTGTAGTGGA
GTATTTGCGAACTTAGATGCCAAGATATTTTGTAATGAGTCTGGTACTTTAACAAGATTTATAATACCAATGTTAGCAGT
GCAGTCTACAGGTAAATATTACGTATATGCCAAGCAAAGAATGATGGATAGACCCTTAGCAGATCAACTAAAACCGCTTG
AAAAGTTAGGTATGCTAGCAAATTACCATCAAAAGGCTTATGCTATGCCTTTGACAATAATAGCTAAATCTTTGGATGGT
GGTTATATAGAAGTTGATGGCGAGAAGAGTTCGCAATTTGCCTCAGGTTTGCTGATGGCAGCACCATTTATGCACCGTGG
CTTAAGATTAAACTCTATCACAGACCACAAGCAACCGTACTTAGATATGACAACTAAAGTTATGGCAGAGTTTGGTGTGA
CAGTAGATATTGATGAAAATATCTATACTGCCAACAAATCTCAATATATCTCTCCTAGTAATTATGTAGTTGAACCAGAT
GTTTCGACAGCTTCATATTTTTGGGCATTTGCAGCTATCACCGGTTCAACTATCAAGGTTATGCATGTTACTAAAAACTC
TAAGCAAGGTGATATTAAATTTTTAGAAGTACTTGAGAAAATAGGCTGTCAAGTTAATTACTACAATGATGGTATAGAGG
TTACAGGTAATAATCAGCTTCGTGGTATACAAGTTAATATGCGTAATTTCTCTGATACTTTCATGACGCTTGCAGCTATT
GCTTGCTTTGCTAAAGGCGATACGCATATTTCAGGTCTTAGTCATACACGTGGTCAAGAATCAGATCGCATTGCAGCTAT
GGCAGAGGGACTTAGCAAGCTTGGTATCTATGTGGAGACTACTCAAGATAGTATTTTAATCTCGCCAGCTAGAAGTAAAT
TTAAGCCAGCTGAAGTTGATAGTCATAATGATCACCGTATCGCTATGTCTTTAGCACTTTTAGGCTTAAAATATCAAGGT
GTAATAGTAAATAATGCAGCGGCTGTAAGCAAAACTTGCCCAGATTATTTTGATAGAATGAGAGCATTGGTAGGTTAG

Upstream 100 bases:

>100_bases
AATATAATTTAAGTTTTTTGTGCACAGAACCTAATTATTCAAAAAAATACTAGTAGTTATGTTAATATAAACATCAATGT
AATTTTTTTAAATTAAACAA

Downstream 100 bases:

>100_bases
CTATGATAAAAAAAGAGCGTATTATAACCAGATATCTAAGTCAAAGGTGGTATAAAAAAGCTCTTATCATCACAGCTACA
GAGAGTAATTATTTTCATAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKDFILQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSRDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHRGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISPSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG

Sequences:

>Translated_425_residues
MKDFILQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSRDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHRGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISPSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG
>Mature_425_residues
MKDFILQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKELGCQLEHSRDSKTLVIQGCSG
VFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQRMMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDG
GYIEVDGEKSSQFASGLLMAAPFMHRGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISPSNYVVEPD
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQLRGIQVNMRNFSDTFMTLAAI
ACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVETTQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQG
VIVNNAAAVSKTCPDYFDRMRALVG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=424, Percent_Identity=35.8490566037736, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=31.236442516269, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46816; Mature: 46816

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFILQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKEL
CCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHH
GCQLEHSRDSKTLVIQGCSGVFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQR
CCEECCCCCCCEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
MMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDGGYIEVDGEKSSQFASGLLMA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCHHHHHHHHHH
APFMHRGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISPSNYVVEPD
HHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCEECCC
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQL
CCHHHHHHHHEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCE
RGIQVNMRNFSDTFMTLAAIACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVET
EEEEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQGVIVNNAAAVSKTCPDYFDRM
CCCEEEEECCCCCCCCCCCCCCCCCHHHEEHHHHCEEECCEEEECCHHHHHCCHHHHHHH
RALVG
HHHCC
>Mature Secondary Structure
MKDFILQIKSQIKQQVYLDGSKSISNRSLIIAAMAQGQTKFENLPNSADVLACIAALKEL
CCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHH
GCQLEHSRDSKTLVIQGCSGVFANLDAKIFCNESGTLTRFIIPMLAVQSTGKYYVYAKQR
CCEECCCCCCCEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
MMDRPLADQLKPLEKLGMLANYHQKAYAMPLTIIAKSLDGGYIEVDGEKSSQFASGLLMA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCHHHHHHHHHH
APFMHRGLRLNSITDHKQPYLDMTTKVMAEFGVTVDIDENIYTANKSQYISPSNYVVEPD
HHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCCCEECCC
VSTASYFWAFAAITGSTIKVMHVTKNSKQGDIKFLEVLEKIGCQVNYYNDGIEVTGNNQL
CCHHHHHHHHEEECCCEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCE
RGIQVNMRNFSDTFMTLAAIACFAKGDTHISGLSHTRGQESDRIAAMAEGLSKLGIYVET
EEEEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TQDSILISPARSKFKPAEVDSHNDHRIAMSLALLGLKYQGVIVNNAAAVSKTCPDYFDRM
CCCEEEEECCCCCCCCCCCCCCCCCHHHEEHHHHCEEECCEEEECCHHHHHCCHHHHHHH
RALVG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA