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The map label for this gene is ruvA [H]

Identifier: 134302038

GI number: 134302038

Start: 1011933

End: 1012583

Strand: Reverse

Name: ruvA [H]

Synonym: FTW_1070

Alternate gene names: 134302038

Gene position: 1012583-1011933 (Counterclockwise)

Preceding gene: 134302039

Following gene: 134302037

Centisome position: 53.34

GC content: 33.03

Gene sequence:

>651_bases
ATGATAAGTTTTATAAAAGGTGTATTGATAGAGAAAGATCCAACAGCTTTGCTTATTGATGTAAATGGTATTGGTTATGA
AGTTTTTGTACCGATGACAACATTTTATACATTAGGTGATATTGATAGTCAGGTTAGCCTTTATACACATTTTATAGTTC
GTGAAGATGCTCAGCAACTCTATGGGTTTAAATCAAAAGTTGATAAGAAAGTTTTCCAAGAGTTAATTAAAGTCAATGGT
ATAGGAGCTAGAACAGCTATTGCTATTTTATCTGGTATGGATTCAAAAACTCTATTACATTGTATTGAAAATAAAGATTA
TGCTTTATTAGCTACAGTGCCAGGAATTGGTAAAAAAACTGCTGAGCGTTTAGTTGTAGAAATTTATGATAAGTTATTAA
AAATGGCTAATGAGATTTATGCTCAGACTTCAGGTACAACTACAACTAGTCAAGATTCACAAGCACAACAGGCACCAACA
TCTGTAGTATTAGCAAACTCAATATTTAACGAATCCGTTGATGCATTATTGGCATTAGGCTATAAGCAAAAAGATGCTGA
AAAAATGGCTCGCTCTGCTATGGGTGATGCAACTACAGCAGCAGAGGTAATTCGTAAAGCTCTGCAAGGATCAATAAAAT
CAAAAAGATAA

Upstream 100 bases:

>100_bases
TATTTTGTTAGCTCTGTCAATTCTTCCTATCGCTTTTTTAGCAGCACTTATAGTAAGCTTAAAATTATCAACAGTTCAAA
GGGACTAAGGGATATTATTG

Downstream 100 bases:

>100_bases
TAGTTATAATATAAGGGGAAGACAAATGATACTAGCTATAGCATTAATAATGCTATTAATTATTTTTGGCATAATATTTT
TTTTAATAATTAACAAAAAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFIVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR

Sequences:

>Translated_216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFIVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR
>Mature_216_residues
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFIVREDAQQLYGFKSKVDKKVFQELIKVNG
IGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKTAERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPT
SVVLANSIFNESVDALLALGYKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=213, Percent_Identity=41.3145539906103, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 23563; Mature: 23563

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFIVREDAQQL
CCCHHCCEEECCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHH
AERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHC
YKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISFIKGVLIEKDPTALLIDVNGIGYEVFVPMTTFYTLGDIDSQVSLYTHFIVREDAQQL
CCCHHCCEEECCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YGFKSKVDKKVFQELIKVNGIGARTAIAILSGMDSKTLLHCIENKDYALLATVPGIGKKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCHHH
AERLVVEIYDKLLKMANEIYAQTSGTTTTSQDSQAQQAPTSVVLANSIFNESVDALLALG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHC
YKQKDAEKMARSAMGDATTAAEVIRKALQGSIKSKR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA