Click here to switch to the map view.

The map label for this gene is ygdL [C]

Identifier: 134301984

GI number: 134301984

Start: 953776

End: 954321

Strand: Direct

Name: ygdL [C]

Synonym: FTW_1003

Alternate gene names: 134301984

Gene position: 953776-954321 (Clockwise)

Preceding gene: 134301983

Following gene: 134301985

Centisome position: 50.24

GC content: 36.45

Gene sequence:

>546_bases
ATGATAAATGCTATCACCCAAAGAACCGCGATCTTAGTCAACAATAATGGTCTAGAAAAACTTGAGAATGCTAATATTTT
TATTGCCGGATGTGGCGGTGTTGGTTCTTTTGTAATCGAAGCTCTTGCTAGAGCCGGTATTGGTAAATTGACAATTGTTG
ATATGGATGTTGTCGACCCATCTAATATTAATCGTCAACTCGTTGCACTTCATAGCACTATAGGCGTACCAAAAGTAGAG
GTTATGCAACAACGTATAATAGATATCAACCCACAATGCAAAGTTACTGCACTACAAACTTTTATTAATCCTGATAATAG
TCAAGATTTACTTACTCAGCAAAACTATGATTATGTTATTGATGCCATAGATACACTAAACGCAAAGGTAAATTTAGTCA
AAACTGCTCATCAATTAGATATCAAAACAATATCTAGTATGGGAGCGGGTGGCAAAACTGATCCAACTCAAATAAAAGTA
GCTGACATCTACAATACTGATGTTTGCGCCCTAGCAAGAGCTATGCGAACACGCCTAAAAAAATAG

Upstream 100 bases:

>100_bases
ACTAGATATAAATGAGGTTGATCATGTCACCGGTGAAACTTATGCTAATCTATTTGCTTATAATTATATAAACGATATGA
ACAAGGTGTATTCATAAATT

Downstream 100 bases:

>100_bases
AAAGTAAAAAAAGGTATTAAAGCAGTATTCTCTACACAAAAAGGCATATCGCCTCTTCCTCCATTAGATCAACAACCTAG
CCAACAAGGTAGATCTAGAG

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MINAITQRTAILVNNNGLEKLENANIFIAGCGGVGSFVIEALARAGIGKLTIVDMDVVDPSNINRQLVALHSTIGVPKVE
VMQQRIIDINPQCKVTALQTFINPDNSQDLLTQQNYDYVIDAIDTLNAKVNLVKTAHQLDIKTISSMGAGGKTDPTQIKV
ADIYNTDVCALARAMRTRLKK

Sequences:

>Translated_181_residues
MINAITQRTAILVNNNGLEKLENANIFIAGCGGVGSFVIEALARAGIGKLTIVDMDVVDPSNINRQLVALHSTIGVPKVE
VMQQRIIDINPQCKVTALQTFINPDNSQDLLTQQNYDYVIDAIDTLNAKVNLVKTAHQLDIKTISSMGAGGKTDPTQIKV
ADIYNTDVCALARAMRTRLKK
>Mature_181_residues
MINAITQRTAILVNNNGLEKLENANIFIAGCGGVGSFVIEALARAGIGKLTIVDMDVVDPSNINRQLVALHSTIGVPKVE
VMQQRIIDINPQCKVTALQTFINPDNSQDLLTQQNYDYVIDAIDTLNAKVNLVKTAHQLDIKTISSMGAGGKTDPTQIKV
ADIYNTDVCALARAMRTRLKK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI150417996, Length=160, Percent_Identity=28.125, Blast_Score=64, Evalue=5e-11,
Organism=Homo sapiens, GI4885649, Length=142, Percent_Identity=25.3521126760563, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1789177, Length=181, Percent_Identity=44.1988950276243, Blast_Score=147, Evalue=3e-37,
Organism=Escherichia coli, GI87082356, Length=139, Percent_Identity=33.0935251798561, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787048, Length=117, Percent_Identity=32.4786324786325, Blast_Score=70, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71984476, Length=116, Percent_Identity=32.7586206896552, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321790, Length=176, Percent_Identity=32.3863636363636, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322825, Length=171, Percent_Identity=37.4269005847953, Blast_Score=104, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321903, Length=134, Percent_Identity=33.5820895522388, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582879, Length=138, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24660640, Length=133, Percent_Identity=27.0676691729323, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 19632; Mature: 19632

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAITQRTAILVNNNGLEKLENANIFIAGCGGVGSFVIEALARAGIGKLTIVDMDVVDP
CCCCCCCCEEEEEECCCHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCC
SNINRQLVALHSTIGVPKVEVMQQRIIDINPQCKVTALQTFINPDNSQDLLTQQNYDYVI
CCCCCEEEEEEHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCEE
DAIDTLNAKVNLVKTAHQLDIKTISSMGAGGKTDPTQIKVADIYNTDVCALARAMRTRLK
EHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MINAITQRTAILVNNNGLEKLENANIFIAGCGGVGSFVIEALARAGIGKLTIVDMDVVDP
CCCCCCCCEEEEEECCCHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCC
SNINRQLVALHSTIGVPKVEVMQQRIIDINPQCKVTALQTFINPDNSQDLLTQQNYDYVI
CCCCCEEEEEEHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCCEE
DAIDTLNAKVNLVKTAHQLDIKTISSMGAGGKTDPTQIKVADIYNTDVCALARAMRTRLK
EHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]