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The map label for this gene is ycgM [H]

Identifier: 134301923

GI number: 134301923

Start: 896109

End: 896702

Strand: Reverse

Name: ycgM [H]

Synonym: FTW_0930

Alternate gene names: 134301923

Gene position: 896702-896109 (Counterclockwise)

Preceding gene: 134301924

Following gene: 134301922

Centisome position: 47.23

GC content: 28.28

Gene sequence:

>594_bases
ATGCAAATTGATCTAACAAAGTCAAAAGTAATTTGTGTCGGAAGAAATTACGTTGAGCATATTCATGAGCTTAATAATGA
AGTTCCTGACAATCCAGTTATTTTTATAAAACCTAATTCAAGTATAACTAAAACTCTAAAATTATCTTCAAAAAGAGAAA
CTCACTATGAATGTGAAATAGTTTTTATTTTTGATAATAATTCAAATATAAAAGCCGTCGGTTTGGGATTAGATTTGACT
GATAGAAATTTACAGTCAAAACTTAAGGCAAAAGGACTACCATGGGAATTGGCAAAAGCTTTTGATAATAGTGCGGTGAT
TAGTGAGTTTGTTGCAATAGATAGTAAAGATATTGCATTTTTGAATTTCAAAGCATACAAGAATGATATTCTAATTCAGC
AAGGTAGTTATGATTTAATGATCTATAAACCTCAACAAATTATAGATTTTTTGCAGCAAAATGAAATCTCAATATGTGAA
AATGATTTACTAATGACTGGAACTCCTAAAGGTGTTGGTGTAGTAAATACTGGTGATAAGTTTAAAATCGAGTTATTTTG
TAGAGATAAAAAAATATTAGCAACAACTTTTTAG

Upstream 100 bases:

>100_bases
AGCCGATGAAACAGTTAGAAAAGTATATCTAGGTGAAGATTTCAAATTATAAAAAATTCAATTATAAGTTTTATTGTCTA
TTTGTTGAGGAAAGCAAAAA

Downstream 100 bases:

>100_bases
GTATATAAAAATATGTGGGCAATTGTAGGAAGTAGTGGTTTTGAATCTTTTGATGACTTTGAGATTATAGAAGAATTGCC
ACGAGAAACGCCATTTGGTT

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DRNLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF

Sequences:

>Translated_197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DRNLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF
>Mature_197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DRNLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=188, Percent_Identity=32.9787234042553, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI66348062, Length=188, Percent_Identity=32.9787234042553, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI13654274, Length=188, Percent_Identity=32.9787234042553, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI156231349, Length=200, Percent_Identity=28.5, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI40786394, Length=200, Percent_Identity=27.5, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1787428, Length=197, Percent_Identity=34.010152284264, Blast_Score=114, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=29.0816326530612, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324161, Length=236, Percent_Identity=32.2033898305085, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571789, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28572127, Length=190, Percent_Identity=25.7894736842105, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 22321; Mature: 22321

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEI
CEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEE
VFIFDNNSNIKAVGLGLDLTDRNLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAF
EEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCEEE
LNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICENDLLMTGTPKGVGVVNTGDK
EEEEECCCEEEEECCCEEEEEECHHHHHHHHHCCCCEEECCCEEEECCCCCCEEEECCCE
FKIELFCRDKKILATTF
EEEEEEEECCEEEEECC
>Mature Secondary Structure
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEI
CEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEE
VFIFDNNSNIKAVGLGLDLTDRNLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAF
EEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCEEE
LNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICENDLLMTGTPKGVGVVNTGDK
EEEEECCCEEEEECCCEEEEEECHHHHHHHHHCCCCEEECCCEEEECCCCCCEEEECCCE
FKIELFCRDKKILATTF
EEEEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]