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The map label for this gene is trpGD [H]

Identifier: 134301857

GI number: 134301857

Start: 819034

End: 819588

Strand: Direct

Name: trpGD [H]

Synonym: FTW_0840

Alternate gene names: 134301857

Gene position: 819034-819588 (Clockwise)

Preceding gene: 134301856

Following gene: 134301861

Centisome position: 43.14

GC content: 31.53

Gene sequence:

>555_bases
ATGGTTTTATATATCGATCATTATGATTCATTTAGTAGTACGATTGTCGATTATATAACTTATCTTGGCTATCAAGTGTC
GATGCTAAAAACTGATGAGCAAATTGATAATATTGACCAATATTCTCATATCATTATTGGTCCAGGACCAGGTCACCCGG
ATGAGCTTAAAAATATCTATCCAATTATTGAATACTGTCAGCAAAAAAAATTACCTTTGTTAGGAATATGTTTAGGTCAT
CAGCTTATTGCTCAATATTATGGTGCAAAAATCATAAAAGCTAAACAAATATACCATGGCAAACTCTCCGAGATTAAACA
GCTTCAATCATCAGCATTATATAAAGATCATCCAGTGAAATTTGCTGTAACACGTTATCATTCATTAATTGTTAATGATA
TTAAAGAGCCTTTGATTACTTTAGCTGCAACCGATAATCATGAAATTATGGCTTTTGCTCATCAAAATGCAAAGATTTTT
GGGGTACAATATCATCCAGAAGCATATTTGACAGAATATGGCTTAGCAACATTGAAAAACTTCTTGAGTATTTGA

Upstream 100 bases:

>100_bases
CAAGCAAAAAGCCTAAATTTAAATGATCTAAAAACCGCTGATAAAATATATCTTATCAATAGTGTTAGAGGTTTGATACC
AGCGTATTTGGGGATTTAAG

Downstream 100 bases:

>100_bases
CTAAACTTTTTGTGGTTTTATATAAAAGCTTAAAATATTAGCAATGATTAGCAAACCCAAGAATAAACCATAAGCTATTT
TATAACTCAAAAAAGTAGTA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIYPIIEYCQQKKLPLLGICLGH
QLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVKFAVTRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIF
GVQYHPEAYLTEYGLATLKNFLSI

Sequences:

>Translated_184_residues
MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIYPIIEYCQQKKLPLLGICLGH
QLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVKFAVTRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIF
GVQYHPEAYLTEYGLATLKNFLSI
>Mature_184_residues
MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIYPIIEYCQQKKLPLLGICLGH
QLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVKFAVTRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIF
GVQYHPEAYLTEYGLATLKNFLSI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=37.4331550802139, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=32.9787234042553, Blast_Score=99, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322638, Length=190, Percent_Identity=35.7894736842105, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=29.8578199052133, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21020; Mature: 21020

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIY
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCHHHHCHHHCCEEEEECCCCCHHHHHHHH
PIIEYCQQKKLPLLGICLGHQLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVK
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHCCHHHHHHHHHHHCCCCCCCCC
FAVTRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIFGVQYHPEAYLTEYGLATLKN
HHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHH
FLSI
HHCC
>Mature Secondary Structure
MVLYIDHYDSFSSTIVDYITYLGYQVSMLKTDEQIDNIDQYSHIIIGPGPGHPDELKNIY
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCHHHHCHHHCCEEEEECCCCCHHHHHHHH
PIIEYCQQKKLPLLGICLGHQLIAQYYGAKIIKAKQIYHGKLSEIKQLQSSALYKDHPVK
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHCCHHHHHHHHHHHCCCCCCCCC
FAVTRYHSLIVNDIKEPLITLAATDNHEIMAFAHQNAKIFGVQYHPEAYLTEYGLATLKN
HHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHH
FLSI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]