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The map label for this gene is infC [H]

Identifier: 134301673

GI number: 134301673

Start: 608033

End: 608569

Strand: Direct

Name: infC [H]

Synonym: FTW_0613

Alternate gene names: 134301673

Gene position: 608033-608569 (Clockwise)

Preceding gene: 134301672

Following gene: 134301674

Centisome position: 32.03

GC content: 40.22

Gene sequence:

>537_bases
CTGCGGAGGAAAAAGATTATTAAAACGGATAAAAAAGCACCTATAAATGAGCAAATTAAAGCAAAAGAGGTGCGTCTAGT
TGGTGTTGATGGTCAACAAATAGGTGTTGTATCTATCAATGAGGCTTTAGCGTTGGCTGAAGAGGCTGATGTTGATTTGG
TTGAAATGGTAGCAAATGCTAATCCGCCAGTGTGTCGTTTGATGGACTACGGTAAGTACTTGTTTGAACAAGGCAAGAAA
AAAGCACAAGCTAAAAAGAACCAAAAGCAGACTCAGGTGAAAGAGGTGAAGCTCAGACCTGTGACTGATGTTGGGGATTA
TCAGGTAAAACTACGCAACCTGATAAAATTCCTTGAAAAAGGCGATAAAGTAAAAGTCACATTGAGATTTAGAGGTAGAG
AAATGTCACATAAAGAGCTGGGTATGGAAATGCTTCAGCGTATGGCAAATGATGCTGCTGAATACGGTGTGGTGGAACAC
CAACCTAAACTGGAAGGTCGCCAAATGATTATGGTTTTAGGACCAAAGAAAAAGTAG

Upstream 100 bases:

>100_bases
CACAATAAGAAAGCATAGCGGCGAAGATCTAGGACAGATGTCTGTAGATGATTTTTGTGCTTTTTTAGATAAGCAAATAC
AGGCTAAAGAATAATAATTT

Downstream 100 bases:

>100_bases
TAAATAAATATAACAATTAATATAAAATGCGGAGTATTAAATATGCCAAAGTTAAAAACTAAAAGTGGTGCTGCTAAGCG
CTTTAAAAAAACTGGTAAGG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRRKKIIKTDKKAPINEQIKAKEVRLVGVDGQQIGVVSINEALALAEEADVDLVEMVANANPPVCRLMDYGKYLFEQGKK
KAQAKKNQKQTQVKEVKLRPVTDVGDYQVKLRNLIKFLEKGDKVKVTLRFRGREMSHKELGMEMLQRMANDAAEYGVVEH
QPKLEGRQMIMVLGPKKK

Sequences:

>Translated_178_residues
MRRKKIIKTDKKAPINEQIKAKEVRLVGVDGQQIGVVSINEALALAEEADVDLVEMVANANPPVCRLMDYGKYLFEQGKK
KAQAKKNQKQTQVKEVKLRPVTDVGDYQVKLRNLIKFLEKGDKVKVTLRFRGREMSHKELGMEMLQRMANDAAEYGVVEH
QPKLEGRQMIMVLGPKKK
>Mature_178_residues
MRRKKIIKTDKKAPINEQIKAKEVRLVGVDGQQIGVVSINEALALAEEADVDLVEMVANANPPVCRLMDYGKYLFEQGKK
KAQAKKNQKQTQVKEVKLRPVTDVGDYQVKLRNLIKFLEKGDKVKVTLRFRGREMSHKELGMEMLQRMANDAAEYGVVEH
QPKLEGRQMIMVLGPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=179, Percent_Identity=60.8938547486033, Blast_Score=206, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20286; Mature: 20286

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKKIIKTDKKAPINEQIKAKEVRLVGVDGQQIGVVSINEALALAEEADVDLVEMVANA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCHHHHHHHHCC
NPPVCRLMDYGKYLFEQGKKKAQAKKNQKQTQVKEVKLRPVTDVGDYQVKLRNLIKFLEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GDKVKVTLRFRGREMSHKELGMEMLQRMANDAAEYGVVEHQPKLEGRQMIMVLGPKKK
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRRKKIIKTDKKAPINEQIKAKEVRLVGVDGQQIGVVSINEALALAEEADVDLVEMVANA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCHHHHHHHHCC
NPPVCRLMDYGKYLFEQGKKKAQAKKNQKQTQVKEVKLRPVTDVGDYQVKLRNLIKFLEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GDKVKVTLRFRGREMSHKELGMEMLQRMANDAAEYGVVEHQPKLEGRQMIMVLGPKKK
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA