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The map label for this gene is recD [H]

Identifier: 134301566

GI number: 134301566

Start: 486334

End: 488175

Strand: Direct

Name: recD [H]

Synonym: FTW_0495

Alternate gene names: 134301566

Gene position: 486334-488175 (Clockwise)

Preceding gene: 134301565

Following gene: 134301572

Centisome position: 25.62

GC content: 31.43

Gene sequence:

>1842_bases
ATGTATAAAACTTTCCATAAAGCTTGTGAGCAATTAGCAGATATTAGAGCCATAGATTTTTTCTTTGCTAAAGAGGTGTT
TGATTTAGTCAAAAAGACTACTCCGTCTATGACCACTTTATCAAGTGAGTCATATCTACCCTTTCACGGAGCAAAGGGGA
ATGATTTGGAACAAAAAAGTAATGAAATTTTATTTCATATTTTGATGAAGCTTATGCATGTGTATAGTCATGGTCATAGC
TGTTTGAAGATAGCAGATATATCAAATAAAACTATTTTTGCTTCAGAGCAAAGTAATCAGAGTGATGCTAAAGTAGGCTT
TAAAATGCCAAGCTCTGATAAAATTGCAAGTATTTTAGATAACTTAAATTACGATAATTTACCTATATATTTTGCCAAAC
AGTATGATTCTTTGTATATTAAAAGATTGTGGAATTATGAGAATGAAATGGCTAACTTTATAAAATTAAAAACAATCCAA
AATACTCAAAAAGACAATCGTATTGAAGAAGTTGTAGACAAACTATTTGAACCTGCTGGTGAAATCAACTGGCAAAAACA
GGCGGTTATCAAAAGTCTAAATTATAATTTTAGTATTATCTCAGGTGGACCTGGTACAGGTAAGACAACTACAGTCGCAA
AGCTTTTACTTGCTATACAAATGCTTAATCAAAATCAGCAAAGAATAGCGCTTTTAGCACCAACTGGTAAGGCTGCTCAG
AGAATGACAGAGTCATTAAAAAATACTCTAGCAACTGTCATTCCGTCAAGCTTGACCACAGAATCTACTATACAAAAAAA
TGATATCTTTAAACAAGTTCAGGATGAACTTAATAGTGTTGCTCAGTATCTTAATAATCTAGAAGCACAAACTATACACA
GATTTTTAGGCTTAAGACCAAACTCTACTTATGTTAAATATAACCAACAATCTAAAGCTCCATTCGATGTTATTATTGTT
GATGAAGCTTCGATGCTTGATATGAATATTTTTATCAAGTTAATTAGAGCTGTAGCAGATAATACTAAGTTGATATTAAT
AGGTGATACTAATCAGTTACCATCTGTTGAGGCTGGGAGTCTTTTAGCAAACTTTACACATGATAAATATGGTAGCATTA
CGCCATATACAACATTACTTATCAAAAACTATCGTTCACAACAATATATAAATAATCTTGCAGCCTCAGTCCTAAAAGGC
GATGTTAATATTGATAGTCAACAAAATGAAAATATTAAATTTCATAGTCTAAGAAATTTAGATATTTATTTAAGAGAGTA
TGCAAAGAGATATTCACAGCTTGAAAAGTGCCGTGACTACAAAGAGGCTCTTACAGAGCTGAATAAATTTAGAATACTTG
TGGCTAACAAAAACCTAGAAATTGGTACAGATAAGTTAAATCAGAAAATTGAGAAGTTTATGTCTAAGCCTATAGATTCT
AACTATAAGGGTAAACCAATTATGATAACTCAAAATAGTTATTCATTAGGGTTATTTAATGGAGATGTAGGGATTATGTG
GCCTGATGATACTGGTAAGCTCCGAGCATATTTTGATGGTAAAGATGCTAAGGCATTTAGTCTAAATATGCTACCAAAAT
ATGAAAGTGTTTATGCGATGACAATTCATAAAACTCAAGGCTCAGAGTTTGATGAAATCGTGATTATTCTTCCAGCAGAA
GATAATGAAGCGCTAAGTAAACAACTTTTGTATACAGCTATTACTAGAGCAAAATATAAATTAACGATTATATCTGAACA
AAGTAGCTTAAGAGATATTGCTCAGAAAGATATTAAGAGAAATTCAAATATCAGTGAATTAGTTAGCTTGAGCACTCAAT
AA

Upstream 100 bases:

>100_bases
TTTTATCTTAGAGGTATGAAAGATGGTTATGGAGTTTATCGAGCTAGACCAAATTTAGAGATTATCAACAAACTTGCTAG
TTTATTTAATGGAGATGATA

Downstream 100 bases:

>100_bases
CTTAGAAATTACTTATTCATTTGCCAGATTATTCTAAGTCCATGAAGTAATAAATCAGAGATGATTACATCAAAATATTG
TTCTTTCTCAAAAATATGAG

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MYKTFHKACEQLADIRAIDFFFAKEVFDLVKKTTPSMTTLSSESYLPFHGAKGNDLEQKSNEILFHILMKLMHVYSHGHS
CLKIADISNKTIFASEQSNQSDAKVGFKMPSSDKIASILDNLNYDNLPIYFAKQYDSLYIKRLWNYENEMANFIKLKTIQ
NTQKDNRIEEVVDKLFEPAGEINWQKQAVIKSLNYNFSIISGGPGTGKTTTVAKLLLAIQMLNQNQQRIALLAPTGKAAQ
RMTESLKNTLATVIPSSLTTESTIQKNDIFKQVQDELNSVAQYLNNLEAQTIHRFLGLRPNSTYVKYNQQSKAPFDVIIV
DEASMLDMNIFIKLIRAVADNTKLILIGDTNQLPSVEAGSLLANFTHDKYGSITPYTTLLIKNYRSQQYINNLAASVLKG
DVNIDSQQNENIKFHSLRNLDIYLREYAKRYSQLEKCRDYKEALTELNKFRILVANKNLEIGTDKLNQKIEKFMSKPIDS
NYKGKPIMITQNSYSLGLFNGDVGIMWPDDTGKLRAYFDGKDAKAFSLNMLPKYESVYAMTIHKTQGSEFDEIVIILPAE
DNEALSKQLLYTAITRAKYKLTIISEQSSLRDIAQKDIKRNSNISELVSLSTQ

Sequences:

>Translated_613_residues
MYKTFHKACEQLADIRAIDFFFAKEVFDLVKKTTPSMTTLSSESYLPFHGAKGNDLEQKSNEILFHILMKLMHVYSHGHS
CLKIADISNKTIFASEQSNQSDAKVGFKMPSSDKIASILDNLNYDNLPIYFAKQYDSLYIKRLWNYENEMANFIKLKTIQ
NTQKDNRIEEVVDKLFEPAGEINWQKQAVIKSLNYNFSIISGGPGTGKTTTVAKLLLAIQMLNQNQQRIALLAPTGKAAQ
RMTESLKNTLATVIPSSLTTESTIQKNDIFKQVQDELNSVAQYLNNLEAQTIHRFLGLRPNSTYVKYNQQSKAPFDVIIV
DEASMLDMNIFIKLIRAVADNTKLILIGDTNQLPSVEAGSLLANFTHDKYGSITPYTTLLIKNYRSQQYINNLAASVLKG
DVNIDSQQNENIKFHSLRNLDIYLREYAKRYSQLEKCRDYKEALTELNKFRILVANKNLEIGTDKLNQKIEKFMSKPIDS
NYKGKPIMITQNSYSLGLFNGDVGIMWPDDTGKLRAYFDGKDAKAFSLNMLPKYESVYAMTIHKTQGSEFDEIVIILPAE
DNEALSKQLLYTAITRAKYKLTIISEQSSLRDIAQKDIKRNSNISELVSLSTQ
>Mature_613_residues
MYKTFHKACEQLADIRAIDFFFAKEVFDLVKKTTPSMTTLSSESYLPFHGAKGNDLEQKSNEILFHILMKLMHVYSHGHS
CLKIADISNKTIFASEQSNQSDAKVGFKMPSSDKIASILDNLNYDNLPIYFAKQYDSLYIKRLWNYENEMANFIKLKTIQ
NTQKDNRIEEVVDKLFEPAGEINWQKQAVIKSLNYNFSIISGGPGTGKTTTVAKLLLAIQMLNQNQQRIALLAPTGKAAQ
RMTESLKNTLATVIPSSLTTESTIQKNDIFKQVQDELNSVAQYLNNLEAQTIHRFLGLRPNSTYVKYNQQSKAPFDVIIV
DEASMLDMNIFIKLIRAVADNTKLILIGDTNQLPSVEAGSLLANFTHDKYGSITPYTTLLIKNYRSQQYINNLAASVLKG
DVNIDSQQNENIKFHSLRNLDIYLREYAKRYSQLEKCRDYKEALTELNKFRILVANKNLEIGTDKLNQKIEKFMSKPIDS
NYKGKPIMITQNSYSLGLFNGDVGIMWPDDTGKLRAYFDGKDAKAFSLNMLPKYESVYAMTIHKTQGSEFDEIVIILPAE
DNEALSKQLLYTAITRAKYKLTIISEQSSLRDIAQKDIKRNSNISELVSLSTQ

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=524, Percent_Identity=35.3053435114504, Blast_Score=253, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 69655; Mature: 69655

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKTFHKACEQLADIRAIDFFFAKEVFDLVKKTTPSMTTLSSESYLPFHGAKGNDLEQKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHH
NEILFHILMKLMHVYSHGHSCLKIADISNKTIFASEQSNQSDAKVGFKMPSSDKIASILD
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHH
NLNYDNLPIYFAKQYDSLYIKRLWNYENEMANFIKLKTIQNTQKDNRIEEVVDKLFEPAG
CCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHCCCC
EINWQKQAVIKSLNYNFSIISGGPGTGKTTTVAKLLLAIQMLNQNQQRIALLAPTGKAAQ
CCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
RMTESLKNTLATVIPSSLTTESTIQKNDIFKQVQDELNSVAQYLNNLEAQTIHRFLGLRP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
NSTYVKYNQQSKAPFDVIIVDEASMLDMNIFIKLIRAVADNTKLILIGDTNQLPSVEAGS
CCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH
LLANFTHDKYGSITPYTTLLIKNYRSQQYINNLAASVLKGDVNIDSQQNENIKFHSLRNL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
DIYLREYAKRYSQLEKCRDYKEALTELNKFRILVANKNLEIGTDKLNQKIEKFMSKPIDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCCC
NYKGKPIMITQNSYSLGLFNGDVGIMWPDDTGKLRAYFDGKDAKAFSLNMLPKYESVYAM
CCCCCEEEEECCCCEEEEEECCEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCEEEE
TIHKTQGSEFDEIVIILPAEDNEALSKQLLYTAITRAKYKLTIISEQSSLRDIAQKDIKR
EEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHC
NSNISELVSLSTQ
CCCHHHHHHCCCC
>Mature Secondary Structure
MYKTFHKACEQLADIRAIDFFFAKEVFDLVKKTTPSMTTLSSESYLPFHGAKGNDLEQKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHH
NEILFHILMKLMHVYSHGHSCLKIADISNKTIFASEQSNQSDAKVGFKMPSSDKIASILD
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHH
NLNYDNLPIYFAKQYDSLYIKRLWNYENEMANFIKLKTIQNTQKDNRIEEVVDKLFEPAG
CCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHCCCC
EINWQKQAVIKSLNYNFSIISGGPGTGKTTTVAKLLLAIQMLNQNQQRIALLAPTGKAAQ
CCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
RMTESLKNTLATVIPSSLTTESTIQKNDIFKQVQDELNSVAQYLNNLEAQTIHRFLGLRP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
NSTYVKYNQQSKAPFDVIIVDEASMLDMNIFIKLIRAVADNTKLILIGDTNQLPSVEAGS
CCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH
LLANFTHDKYGSITPYTTLLIKNYRSQQYINNLAASVLKGDVNIDSQQNENIKFHSLRNL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
DIYLREYAKRYSQLEKCRDYKEALTELNKFRILVANKNLEIGTDKLNQKIEKFMSKPIDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCCC
NYKGKPIMITQNSYSLGLFNGDVGIMWPDDTGKLRAYFDGKDAKAFSLNMLPKYESVYAM
CCCCCEEEEECCCCEEEEEECCEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCEEEE
TIHKTQGSEFDEIVIILPAEDNEALSKQLLYTAITRAKYKLTIISEQSSLRDIAQKDIKR
EEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHC
NSNISELVSLSTQ
CCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]