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The map label for this gene is rhtC [H]

Identifier: 134301511

GI number: 134301511

Start: 428665

End: 429300

Strand: Direct

Name: rhtC [H]

Synonym: FTW_0433

Alternate gene names: 134301511

Gene position: 428665-429300 (Clockwise)

Preceding gene: 134301508

Following gene: 134301513

Centisome position: 22.58

GC content: 30.03

Gene sequence:

>636_bases
GTGCTAATCTTTCTAACTATTCTAGCTTTACAAATAAGTTGCCTTATCTTACCTGGTCCAGATTTTTTTGTAACTATCAG
CAACTCTATTAAATTTGGACATAAATCCGGAATATATACAGCAAGCGGCGTTGCTAGTGGAATTTTTTTAAATACATTTA
TTGTCTACTGGTTTGGATCATTGTTATTATACAAACAACCGTTATTATTTAAGATGCTAATTCTCATAGGTGCAGCCTAC
CTTGCATATATCGCTTTTAGCTTGTATAAAAGTATTTTTACAATACAACAACTTAACCCAAACGCTAATCAACATATAAA
AAATCTAGATAATTTTGACAAACCTTCAAATACCAAATTTTTTCTAAATGGCGCTTTTACTAATCTTGCCAATGCTAAAG
TATTAGTCTTTTTTAGTTCGATGCTAAGTCTAGTTGATGAGCTAAACAGTTTTGGTAAAGTTGCGATTTGGATAGCTATA
GCTCTTACAACACTAGTATGGTTTTGTATTGTCGCGACTTTCTTTGGTAACGATAAACTTAGACAAGTATTTTTTAGAAA
TATTAAAAAGATAGAGTTTATTTCAGCTATTTTTATCACTATTTTTGTGATAGTTATATTAGTTGAGCTTTTCTAA

Upstream 100 bases:

>100_bases
GACGCAGATTTTCTTTAGATTTATCACACATTTTTCTAGATTTATTCCAATTTTATTAATACTATTCTATCTCAACTAAA
ACAAAAATAAGAGTATAACA

Downstream 100 bases:

>100_bases
AACAGAACTTTACTCCATCCCAACTTCTCCCTTAGCGTATCATAATAGTTATAATCTTTTGTATGTAATACTGTAACTTT
CTTTCGCGCTTTTTGGATAG

Product: amino acid transporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGSLLLYKQPLLFKMLILIGAAY
LAYIAFSLYKSIFTIQQLNPNANQHIKNLDNFDKPSNTKFFLNGAFTNLANAKVLVFFSSMLSLVDELNSFGKVAIWIAI
ALTTLVWFCIVATFFGNDKLRQVFFRNIKKIEFISAIFITIFVIVILVELF

Sequences:

>Translated_211_residues
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGSLLLYKQPLLFKMLILIGAAY
LAYIAFSLYKSIFTIQQLNPNANQHIKNLDNFDKPSNTKFFLNGAFTNLANAKVLVFFSSMLSLVDELNSFGKVAIWIAI
ALTTLVWFCIVATFFGNDKLRQVFFRNIKKIEFISAIFITIFVIVILVELF
>Mature_211_residues
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGSLLLYKQPLLFKMLILIGAAY
LAYIAFSLYKSIFTIQQLNPNANQHIKNLDNFDKPSNTKFFLNGAFTNLANAKVLVFFSSMLSLVDELNSFGKVAIWIAI
ALTTLVWFCIVATFFGNDKLRQVFFRNIKKIEFISAIFITIFVIVILVELF

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=201, Percent_Identity=26.3681592039801, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786522, Length=198, Percent_Identity=21.7171717171717, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23802; Mature: 23802

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGS
CHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LLLYKQPLLFKMLILIGAAYLAYIAFSLYKSIFTIQQLNPNANQHIKNLDNFDKPSNTKF
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEE
FLNGAFTNLANAKVLVFFSSMLSLVDELNSFGKVAIWIAIALTTLVWFCIVATFFGNDKL
EEECHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RQVFFRNIKKIEFISAIFITIFVIVILVELF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLIFLTILALQISCLILPGPDFFVTISNSIKFGHKSGIYTASGVASGIFLNTFIVYWFGS
CHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
LLLYKQPLLFKMLILIGAAYLAYIAFSLYKSIFTIQQLNPNANQHIKNLDNFDKPSNTKF
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEE
FLNGAFTNLANAKVLVFFSSMLSLVDELNSFGKVAIWIAIALTTLVWFCIVATFFGNDKL
EEECHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RQVFFRNIKKIEFISAIFITIFVIVILVELF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]