Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 134301363

GI number: 134301363

Start: 254534

End: 255412

Strand: Direct

Name: xerD [H]

Synonym: FTW_0244

Alternate gene names: 134301363

Gene position: 254534-255412 (Clockwise)

Preceding gene: 134301362

Following gene: 134301364

Centisome position: 13.41

GC content: 35.04

Gene sequence:

>879_bases
GTGTCCTCAGCTGTTGATGCTTTTCTTGATAATCTCTGGCTTGAGCATGGATTAAGCCAAAATACTATTTCATCTTATCG
TACTGATCTTAAATTCTTACAAAATTATTTTGCAAAAACTGATTTAATTAGTTTAGATTTTGAGCAGTTATATGCGTTTA
TTTCATATCGTTCAAAAAATGGTTATAGCAGTCATTCTAATGCTCGAATGATATCGACATTGCGTAAATTCTATGCTTGG
CTTATCTCAACTGGTCAAACTAATAATAATCCTACAGCTAAGCTAACATTACCAAAATTAGCCAAGAAGTTACCTAAAGA
TATGACAGAAACTGATGTTGAGAGATTGCTTCAAGCTCCTGATATGACAGAGGATGTTGGTATTCGCGATAAAGCAATGC
TTGAACTGATGTATGCTACAGGTTTACGTGTAAGTGAATTGGTCGGGCTTAATATTGATGATATCGATATCAATATTGGG
GTAATTCAGGTAATGGGTAAGGGTTCAAAAGAGCGTATAGTGCCAATAGGTGAGTATGCATTGGAGTATTTGCAAAAATA
TTTTGCAGAAGCTCGCAGGAGTTTATCTAAAAATTTCAAAGAGAAAGCAGTTTTTATCAGTAAGCATGCAAAAAGAATAA
CGCGTCAGTCTTTTTGGCACAGAATCAAAAACTATGCACTTATCGCTGGTATAAATACCGATATTTCGCCTCATACCCTA
AGACATGCATTTGCTACTCACTTACTCAATCATGGGGCTGATTTGAGATCGGTACAGCTATTGCTTGGACATAGTAATGT
TTCAACAACAACTATTTATACACATATATCTCAAAATCGCTTACAAGAGATTTATCAAAAACATCATCCAAGGGGATAA

Upstream 100 bases:

>100_bases
TTTACAATTTGTAAACTCCGCTTTTTCGGATATTTTTGCCTTGTTATATTCCATCTAATTTCAGCTTGCAATCGTCTCAA
AACTCTAGGAAAATCAAAAA

Downstream 100 bases:

>100_bases
AACCTCTACTATTAAGTATTTTATTGTTTTATAAACTAGCTATGATTAGTAAATCTAGCTAATGAAACAATACCTTATTG
TTGATATAATAATATTCGGA

Product: tyrosine recombinase/integrase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKNGYSSHSNARMISTLRKFYAW
LISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAPDMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIG
VIQVMGKGSKERIVPIGEYALEYLQKYFAEARRSLSKNFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTL
RHAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG

Sequences:

>Translated_292_residues
MSSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKNGYSSHSNARMISTLRKFYAW
LISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAPDMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIG
VIQVMGKGSKERIVPIGEYALEYLQKYFAEARRSLSKNFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTL
RHAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG
>Mature_291_residues
SSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKNGYSSHSNARMISTLRKFYAWL
ISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAPDMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIGV
IQVMGKGSKERIVPIGEYALEYLQKYFAEARRSLSKNFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTLR
HAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=49.1408934707904, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=38.5665529010239, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=30.939226519337, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33379; Mature: 33247

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKN
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYSSHSNARMISTLRKFYAWLISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAP
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHCC
DMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIGVIQVMGKGSKERIVPIGEYA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEECEEEEEEECCCCCCCEEECHHHH
LEYLQKYFAEARRSLSKNFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHH
RHAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG
HHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKN
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYSSHSNARMISTLRKFYAWLISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAP
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHCC
DMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIGVIQVMGKGSKERIVPIGEYA
CCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEECEEEEEEECCCCCCCEEECHHHH
LEYLQKYFAEARRSLSKNFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHH
RHAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG
HHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]