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The map label for this gene is nuoH [H]

Identifier: 134301253

GI number: 134301253

Start: 123006

End: 124016

Strand: Direct

Name: nuoH [H]

Synonym: FTW_0113

Alternate gene names: 134301253

Gene position: 123006-124016 (Clockwise)

Preceding gene: 134301252

Following gene: 134301254

Centisome position: 6.48

GC content: 36.5

Gene sequence:

>1011_bases
ATGCTAGGGTATATTTTATGGACATCACTTTATGTATTGTTGATAGTCATTCCTTTGATACTAGTTGTTGCATACTATAC
ATATGCAGAGCGTAAAGTTATCGGTTATATGCAAGATAGAATCGGTCCAAATAGGGTAGGATCTTTTGGTTTATTGCAAC
CTATATTTGATGCGCTTAAGCTTTTTCTCAAAGAGATTATAGTGCCAACAAATTCAAATAGATATTTATTCTTTATTGCA
CCGATTTTAGCTTTTGCTCCGGCATATGCTGCTTGGGCGGTGATTCCTTTCTCTAAAGGTGTTGTTTTATCTGATATGAA
TCTCGGCTTACTATATATATTGGCAATGACTTCATTTTCTATATATGGGATAGTAATTGCTGGTTGGGCATCAAATAGTA
AATACTCATTATTTGGCGCATTAAGAGCTGGAGCTCAGGTTATTTCCTATGAGTTGGCGATGGGTTTTGCTATCGTTGGA
GTTGTCATAGCAGCAGGCTCTATGGGTATAACTGGAATTATTGAAGCTCAAAGCGGTGGTATTTGGCACTGGTATTTTAT
TCCGCTATTTCCATTATTTATTGTGTATTTTATTGCTGGTATAGCAGAGACAAATAGAGCTCCTTTTGATGTTGTTGAGG
GTGAGTCTGAGATAGTTGCTGGACATCATATAGAATATACAGGGTCTAGGTTTGCTTTGTTTTTCTTGGCTGAATATGCA
AATATGATTTTAATTAGTATCCTAACATCAATAATGTTTTTAGGTGGTTGGAATTCGCCATTCCAAGCTACGGCATTAGA
GTCTATATTTGGTTTTGTACCAGGTGTGGTATGGTTATTTGCTAAGACTGGTATATTCATGTTTATGTTCTTATGGGTCA
GAGCTACATACCCTCGTTATAGATATGACCAAATTATGCGTTTAGGTTGGAAGATATTTATACCACTAACGTTTGTATGG
GTTGTTATTGTTGCTTGCATGGTTAGACTTGGTGTAGGACCTTGGTGGTAA

Upstream 100 bases:

>100_bases
AGCTTACAGGCTAAAAATATTATGCTACCAAGAGCACTATTTAAGGACTTTTTAAGTAGTGATAACATTAGTATTAAGCT
GGTAGAGGAGGAGAGATAAT

Downstream 100 bases:

>100_bases
AAAGGATAGTATCATGAGAAATATAACAAATTTTTTAAAGACTTTTCTACTTTGGGAGCTTCTAAAAGGGTTAAAAGTAA
CCGGTAAGCATTTTTTTACT

Product: NADH dehydrogenase I, H subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIA
PILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVG
VVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYA
NMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVW
VVIVACMVRLGVGPWW

Sequences:

>Translated_336_residues
MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIA
PILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVG
VVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYA
NMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVW
VVIVACMVRLGVGPWW
>Mature_336_residues
MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALKLFLKEIIVPTNSNRYLFFIA
PILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFSIYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVG
VVIAAGSMGITGIIEAQSGGIWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYA
NMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRYRYDQIMRLGWKIFIPLTFVW
VVIVACMVRLGVGPWW

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=296, Percent_Identity=44.2567567567568, Blast_Score=242, Evalue=4e-64,
Organism=Escherichia coli, GI1788618, Length=325, Percent_Identity=42.1538461538462, Blast_Score=271, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37642; Mature: 37642

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LFLKEIIVPTNSNRYLFFIAPILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFS
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHH
IYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVGVVIAAGSMGITGIIEAQSGG
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
IWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYA
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEECCEEEECCCHHHHHHHHHHH
NMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RYDQIMRLGWKIFIPLTFVWVVIVACMVRLGVGPWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLGYILWTSLYVLLIVIPLILVVAYYTYAERKVIGYMQDRIGPNRVGSFGLLQPIFDALK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LFLKEIIVPTNSNRYLFFIAPILAFAPAYAAWAVIPFSKGVVLSDMNLGLLYILAMTSFS
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHH
IYGIVIAGWASNSKYSLFGALRAGAQVISYELAMGFAIVGVVIAAGSMGITGIIEAQSGG
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
IWHWYFIPLFPLFIVYFIAGIAETNRAPFDVVEGESEIVAGHHIEYTGSRFALFFLAEYA
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEECCEEEECCCHHHHHHHHHHH
NMILISILTSIMFLGGWNSPFQATALESIFGFVPGVVWLFAKTGIFMFMFLWVRATYPRY
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RYDQIMRLGWKIFIPLTFVWVVIVACMVRLGVGPWW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA