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The map label for this gene is tig

Identifier: 134300402

GI number: 134300402

Start: 2791390

End: 2792697

Strand: Reverse

Name: tig

Synonym: Dred_2563

Alternate gene names: 134300402

Gene position: 2792697-2791390 (Counterclockwise)

Preceding gene: 134300403

Following gene: 134300401

Centisome position: 77.4

GC content: 41.82

Gene sequence:

>1308_bases
ATGAAGGCCACTGCAGAAAGGATCGAAAAAAACACCGTCCTTTTAGAAATCGAGGTAGAGCAGGAGAGAGTTGATCAGGC
TCTTAATCAAGCTTACAAAAAGGTTGTAAAGCAAGTTAATGTTCCAGGATTCCGTAAAGGGAAAGCGCCTAGGAAAATGG
TAGAGCGTTTCGTAGGTACCGAGACTCTATTTGGTGAAGCTGTGGAGATTATTATTCCAGACGCTTATATGGAAGCTCTC
AAAGAGACCGCAACGGAACCCATTGATCAGCCCAAAATTGATATTGTACAGGGCGAAGCTGGCAAAGCCCTTATCTTTAA
AGCTACCGTAGAAGTTAAACCGGAAGTTACTCTAGGCGAGTACAAGGGATTGGAAGTAACAAAGGCTTCCTCTGAAGTTA
CTGACGAAGATGTAGAAAAAGAACTAGCACGTCTCCAAGACCGCCATGCTAAATTGGTAACGTTGGAAGAGGGGGAAATT
AAAAAGGATGATATAACGCTCATTGACTTTACCGGCTATGTAGATGGTGAAGCCTTTGAAGGAGGTCATGCTGAAAACTA
TTCCCTGACCGTTGGTTCCGGCACCTTTATTCCAGGTTTTGAAGAGCAATTGCTGGGTGTAAAGCTGGGGGAAGAAAAAG
AGGTAAATGTTACCTTCCCTGAAGAATATCATGCTGAAAATTTGGCAGGTAAACCTGCAACCTTCAAAGTAAAAATTAAT
GAAATTAAACGTAAAGAACTGGCTTCTTTGGATGATGAGTTTGCAAAAGATGTGAGTGAATTCGATACCTTGGATGAATT
AAAGTCCGATATTCGGAAAAAATTAATGGAAGTCGCCGAAAGAACAGCCAAGTCATCCGTTGAAAACGGTGCAGTAGAAG
CTGCTGTAGAAAAAGCCACTGTTGAAATACCACAAGCAATGATTAGCCAAAAGGTTGAAGAAATGTTGAACAGTATGGGT
CAGCGTTTGGCTCAGCAGGGTATTAACCTGGATCAATATTTCCAATACACCAACACCAGTATGGACGATATGCGCCAGCG
CATGAGACCCGATGCTGAAAAAAATGTTAAGAATGAACTGGTTCTTGATGCCATTGCAAAGGTTGAGAACATTACTGCCA
CTGCAGAAGAAACGAACGAAGAAATTCAAAAAATTGCTGAATACGTTAAGCAAGATGCAGAAATTGTACGTAAAACTCTG
GAATTACAGGGCGAACTGGGGCATATTAATCAAGATATAGCCCGTCGTAAAGTTGTTCAGTTCCTGGTCGAAAATGCCAA
GGTTGTTGAAGGCACAAAAGAGGACTAA

Upstream 100 bases:

>100_bases
GTTAAACTAAGAATAATTAAGGTTGCATCGGCCTAAGGGAGGGTGTAATTTCAGTAGGAAGAATAATAATCTATAGGATA
TTTAAGGAGGAACACTTGAA

Downstream 100 bases:

>100_bases
GTTGAATATATTGGCTAAGTAAAGCCCTGTAGAATAGCTATTAACAAGATCTAGATATATCAAGGAGGCGATGGACTTGT
CAGGCTTAGTACCAATAGTA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKATAERIEKNTVLLEIEVEQERVDQALNQAYKKVVKQVNVPGFRKGKAPRKMVERFVGTETLFGEAVEIIIPDAYMEAL
KETATEPIDQPKIDIVQGEAGKALIFKATVEVKPEVTLGEYKGLEVTKASSEVTDEDVEKELARLQDRHAKLVTLEEGEI
KKDDITLIDFTGYVDGEAFEGGHAENYSLTVGSGTFIPGFEEQLLGVKLGEEKEVNVTFPEEYHAENLAGKPATFKVKIN
EIKRKELASLDDEFAKDVSEFDTLDELKSDIRKKLMEVAERTAKSSVENGAVEAAVEKATVEIPQAMISQKVEEMLNSMG
QRLAQQGINLDQYFQYTNTSMDDMRQRMRPDAEKNVKNELVLDAIAKVENITATAEETNEEIQKIAEYVKQDAEIVRKTL
ELQGELGHINQDIARRKVVQFLVENAKVVEGTKED

Sequences:

>Translated_435_residues
MKATAERIEKNTVLLEIEVEQERVDQALNQAYKKVVKQVNVPGFRKGKAPRKMVERFVGTETLFGEAVEIIIPDAYMEAL
KETATEPIDQPKIDIVQGEAGKALIFKATVEVKPEVTLGEYKGLEVTKASSEVTDEDVEKELARLQDRHAKLVTLEEGEI
KKDDITLIDFTGYVDGEAFEGGHAENYSLTVGSGTFIPGFEEQLLGVKLGEEKEVNVTFPEEYHAENLAGKPATFKVKIN
EIKRKELASLDDEFAKDVSEFDTLDELKSDIRKKLMEVAERTAKSSVENGAVEAAVEKATVEIPQAMISQKVEEMLNSMG
QRLAQQGINLDQYFQYTNTSMDDMRQRMRPDAEKNVKNELVLDAIAKVENITATAEETNEEIQKIAEYVKQDAEIVRKTL
ELQGELGHINQDIARRKVVQFLVENAKVVEGTKED
>Mature_435_residues
MKATAERIEKNTVLLEIEVEQERVDQALNQAYKKVVKQVNVPGFRKGKAPRKMVERFVGTETLFGEAVEIIIPDAYMEAL
KETATEPIDQPKIDIVQGEAGKALIFKATVEVKPEVTLGEYKGLEVTKASSEVTDEDVEKELARLQDRHAKLVTLEEGEI
KKDDITLIDFTGYVDGEAFEGGHAENYSLTVGSGTFIPGFEEQLLGVKLGEEKEVNVTFPEEYHAENLAGKPATFKVKIN
EIKRKELASLDDEFAKDVSEFDTLDELKSDIRKKLMEVAERTAKSSVENGAVEAAVEKATVEIPQAMISQKVEEMLNSMG
QRLAQQGINLDQYFQYTNTSMDDMRQRMRPDAEKNVKNELVLDAIAKVENITATAEETNEEIQKIAEYVKQDAEIVRKTL
ELQGELGHINQDIARRKVVQFLVENAKVVEGTKED

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=313, Percent_Identity=33.2268370607029, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_DESRM (A4J7M0)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113898.1
- ProteinModelPortal:   A4J7M0
- STRING:   A4J7M0
- GeneID:   4958066
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2563
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- PhylomeDB:   A4J7M0
- ProtClustDB:   PRK01490
- BioCyc:   DRED349161:DRED_2563-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 48758; Mature: 48758

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATAERIEKNTVLLEIEVEQERVDQALNQAYKKVVKQVNVPGFRKGKAPRKMVERFVGT
CCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
ETLFGEAVEIIIPDAYMEALKETATEPIDQPKIDIVQGEAGKALIFKATVEVKPEVTLGE
HHHHHCHHHEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEEECCCEECCC
YKGLEVTKASSEVTDEDVEKELARLQDRHAKLVTLEEGEIKKDDITLIDFTGYVDGEAFE
CCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
GGHAENYSLTVGSGTFIPGFEEQLLGVKLGEEKEVNVTFPEEYHAENLAGKPATFKVKIN
CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEHH
EIKRKELASLDDEFAKDVSEFDTLDELKSDIRKKLMEVAERTAKSSVENGAVEAAVEKAT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VEIPQAMISQKVEEMLNSMGQRLAQQGINLDQYFQYTNTSMDDMRQRMRPDAEKNVKNEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
VLDAIAKVENITATAEETNEEIQKIAEYVKQDAEIVRKTLELQGELGHINQDIARRKVVQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLVENAKVVEGTKED
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MKATAERIEKNTVLLEIEVEQERVDQALNQAYKKVVKQVNVPGFRKGKAPRKMVERFVGT
CCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
ETLFGEAVEIIIPDAYMEALKETATEPIDQPKIDIVQGEAGKALIFKATVEVKPEVTLGE
HHHHHCHHHEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEEECCCEECCC
YKGLEVTKASSEVTDEDVEKELARLQDRHAKLVTLEEGEIKKDDITLIDFTGYVDGEAFE
CCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
GGHAENYSLTVGSGTFIPGFEEQLLGVKLGEEKEVNVTFPEEYHAENLAGKPATFKVKIN
CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEHH
EIKRKELASLDDEFAKDVSEFDTLDELKSDIRKKLMEVAERTAKSSVENGAVEAAVEKAT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VEIPQAMISQKVEEMLNSMGQRLAQQGINLDQYFQYTNTSMDDMRQRMRPDAEKNVKNEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
VLDAIAKVENITATAEETNEEIQKIAEYVKQDAEIVRKTLELQGELGHINQDIARRKVVQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLVENAKVVEGTKED
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA