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The map label for this gene is rbsC [H]

Identifier: 134300362

GI number: 134300362

Start: 2742618

End: 2743559

Strand: Reverse

Name: rbsC [H]

Synonym: Dred_2523

Alternate gene names: 134300362

Gene position: 2743559-2742618 (Counterclockwise)

Preceding gene: 134300363

Following gene: 134300361

Centisome position: 76.04

GC content: 46.39

Gene sequence:

>942_bases
ATGGGAAGCCCAAGGAACATAATTCAGCGCTATCACTTAGGGCCATTTCTAGGATTATTAATCATTATCGTAGCCTTAAC
CTTCTTATCCGACCGATTCTTTACCACATCAAATCTATTGAATGTAGCTAGGCAGGTGTCCATTAATACCCTGTTGGGTG
TGGGCATGACCTTTGTAATACTAACTGGTGGAATTGACCTTTCGGTAGGATCCATCTTGGCTTTAGCCGGTGCCTTGGGG
GCAGGTTTTTTGGGACAAGGAAACACTACCTTAATGGTTGTGTTGTATGCCTGTTTGATTGGTCTACTGGCAGGAACTGT
AAATGGAACCATCGTGGCCTATGGGAGGGTGGCACCCTTTATTGCAACCTTGGCAACCATGACATTATTTAGGGGTGCCA
CCCTCATTTATACCGAAGGAAGACCCGTGCGTGCTGTGGCCGAAGGCTTTAATGAACTAGGGGGAGGGTATTTAGGAGCC
ATACCAACACCCGTCATTATTACCAGTGTTATTGTACTTCTGGCCTGGTTTGTATTAACCCAGATGACTCCCGGCAGAAG
AATCTTTGCCCTGGGGGGAAACGAAGAGGCAGCTATTCTAAGTGGTATACGAACCAACCACTATAAAATTATGGTTTACT
CTATTAGTGGTTTATTGGCCGGGTTGGCGGGAGTTATTTTATCTTCCAGATTGTTGTCTGCCCAGCCCACCGCAGGCATA
GGCTACGAGTTAGATGCCATTGCTGCTGTGGTTATTGGTGGCACCAGCTTAACTGGAGGGCAGGGCGGTGTAATCGGTAC
TTTAATTGGTGCTTTAATCATTGGAGTGATCGATAATGGTTTAAATCTGCTAAACGTGTCTTCCTTCTACCAGCAAGCTG
TCAAAGGTCTTATCATTTTGGTTGCGGTTCTGTTAGACCGACGGAATGCTGTGGGGAGGTGA

Upstream 100 bases:

>100_bases
ATCGGGTTTACGTAATGTATGAAGGAAGAGTAACTGGGCACTTTACTCGGGATGAGATAACAGAAGAAGCATTTATGTAC
TGTGCCACAGGAGGTGTGCA

Downstream 100 bases:

>100_bases
TGGGGTAACGATTCTTTTTACATATTTAAGTATATCTTAACAATAGGAGGAAACTAGCATGAAGAAATTTTGGAAACTTG
GAATTGTGTTAGGCAGTCTT

Product: inner-membrane translocator

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGSPRNIIQRYHLGPFLGLLIIIVALTFLSDRFFTTSNLLNVARQVSINTLLGVGMTFVILTGGIDLSVGSILALAGALG
AGFLGQGNTTLMVVLYACLIGLLAGTVNGTIVAYGRVAPFIATLATMTLFRGATLIYTEGRPVRAVAEGFNELGGGYLGA
IPTPVIITSVIVLLAWFVLTQMTPGRRIFALGGNEEAAILSGIRTNHYKIMVYSISGLLAGLAGVILSSRLLSAQPTAGI
GYELDAIAAVVIGGTSLTGGQGGVIGTLIGALIIGVIDNGLNLLNVSSFYQQAVKGLIILVAVLLDRRNAVGR

Sequences:

>Translated_313_residues
MGSPRNIIQRYHLGPFLGLLIIIVALTFLSDRFFTTSNLLNVARQVSINTLLGVGMTFVILTGGIDLSVGSILALAGALG
AGFLGQGNTTLMVVLYACLIGLLAGTVNGTIVAYGRVAPFIATLATMTLFRGATLIYTEGRPVRAVAEGFNELGGGYLGA
IPTPVIITSVIVLLAWFVLTQMTPGRRIFALGGNEEAAILSGIRTNHYKIMVYSISGLLAGLAGVILSSRLLSAQPTAGI
GYELDAIAAVVIGGTSLTGGQGGVIGTLIGALIIGVIDNGLNLLNVSSFYQQAVKGLIILVAVLLDRRNAVGR
>Mature_312_residues
GSPRNIIQRYHLGPFLGLLIIIVALTFLSDRFFTTSNLLNVARQVSINTLLGVGMTFVILTGGIDLSVGSILALAGALGA
GFLGQGNTTLMVVLYACLIGLLAGTVNGTIVAYGRVAPFIATLATMTLFRGATLIYTEGRPVRAVAEGFNELGGGYLGAI
PTPVIITSVIVLLAWFVLTQMTPGRRIFALGGNEEAAILSGIRTNHYKIMVYSISGLLAGLAGVILSSRLLSAQPTAGIG
YELDAIAAVVIGGTSLTGGQGGVIGTLIGALIIGVIDNGLNLLNVSSFYQQAVKGLIILVAVLLDRRNAVGR

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=301, Percent_Identity=54.1528239202658, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1790524, Length=296, Percent_Identity=42.9054054054054, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI145693152, Length=316, Percent_Identity=35.7594936708861, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788896, Length=309, Percent_Identity=37.8640776699029, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1789992, Length=130, Percent_Identity=53.0769230769231, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082395, Length=284, Percent_Identity=35.2112676056338, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693214, Length=250, Percent_Identity=40.4, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787793, Length=281, Percent_Identity=33.0960854092527, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788471, Length=312, Percent_Identity=34.6153846153846, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787794, Length=297, Percent_Identity=30.976430976431, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32371; Mature: 32240

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSPRNIIQRYHLGPFLGLLIIIVALTFLSDRFFTTSNLLNVARQVSINTLLGVGMTFVI
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGGIDLSVGSILALAGALGAGFLGQGNTTLMVVLYACLIGLLAGTVNGTIVAYGRVAPF
EECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHH
IATLATMTLFRGATLIYTEGRPVRAVAEGFNELGGGYLGAIPTPVIITSVIVLLAWFVLT
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHH
QMTPGRRIFALGGNEEAAILSGIRTNHYKIMVYSISGLLAGLAGVILSSRLLSAQPTAGI
CCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
GYELDAIAAVVIGGTSLTGGQGGVIGTLIGALIIGVIDNGLNLLNVSSFYQQAVKGLIIL
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VAVLLDRRNAVGR
HHHHHHHHCCCCC
>Mature Secondary Structure 
GSPRNIIQRYHLGPFLGLLIIIVALTFLSDRFFTTSNLLNVARQVSINTLLGVGMTFVI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGGIDLSVGSILALAGALGAGFLGQGNTTLMVVLYACLIGLLAGTVNGTIVAYGRVAPF
EECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHH
IATLATMTLFRGATLIYTEGRPVRAVAEGFNELGGGYLGAIPTPVIITSVIVLLAWFVLT
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHH
QMTPGRRIFALGGNEEAAILSGIRTNHYKIMVYSISGLLAGLAGVILSSRLLSAQPTAGI
CCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
GYELDAIAAVVIGGTSLTGGQGGVIGTLIGALIIGVIDNGLNLLNVSSFYQQAVKGLIIL
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VAVLLDRRNAVGR
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]