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The map label for this gene is prmA

Identifier: 134300333

GI number: 134300333

Start: 2713203

End: 2714129

Strand: Reverse

Name: prmA

Synonym: Dred_2494

Alternate gene names: 134300333

Gene position: 2714129-2713203 (Counterclockwise)

Preceding gene: 134300334

Following gene: 134300332

Centisome position: 75.22

GC content: 46.71

Gene sequence:

>927_bases
TTGAATTGGCTCGAAATAGCCGTCCATGTATGCCCTGAAGGTATCGACATGGTAAGTAATATATTTGATGAACTGGGTGC
CGGTGGGGTTGTGATAGAGGACCCGGCTTTAATAAACCGGTATATAGAAGCCAACATTTGGGACCATTATGAGTTTCCAC
CCGAGGTCCTAAATCGTCCCCAACCAATCGTAAAAGCTTACCTACCCGAAGGCCCCAACTTGGAGAACAAGCTGGTTCTT
TTACAGGAACGACTGACCGGGCTACCCTTGGATGCAGTGCCTACTTTTGAAAGACGCCAGGTAGCCGAAGAGGATTGGGC
CACCGCCTGGATGAAATACTATAAGCCGGTGGAGATTGGTCAAAAACTGGCTGTTAAGCCCAGTTGGGAAGATTATGTGC
CAGAGGATGGGAGAATTGTTCTGGAAATGGATCCTGGCATGGCCTTTGGCTGTGGTAATCATCCCACCACCACTATGTGT
ATGGAATACCTGGAGGGTATTATCCAGGGGGGGGAATCGGTGGCAGATGTGGGAACCGGCACAGGGATTCTTGCCATCAC
TTCTGCCAAATTAGGTGCTGCTAGGGTTTTAGCAGTGGATTTGGATGAAGTGGCTGTCAAAGTATCCCAGGAAAATGTGG
AGCGGAATGGCGTTCAAGATATAGTTGAAGTGTTTCATGGCAACTTGTTGGATAAAGTGGAAAGCAAGGTTGATGTTGTA
ATCGCCAATATTGTTGCCAATGTCATTATGATTCTGGCCCCTGATGTGCCACGGATTTTAAAACACGGTGGTTATTTTAT
TACATCCGGTATTATTCAGTTTCGTGCTGAAGAAGTCCGGCAAAAGTTGGAACAAACCGGTTTTAAAATTCTAGGACGCA
AGGAAGACGGGGAATGGGTTTCCTACCTATGTATTTTGGAGGGATAA

Upstream 100 bases:

>100_bases
CATAGGCTGAAGGCTGAAAGCTGACAACAAAAATAAAACCATTTCAGATGGAAGTTACCCTAGACTCACCTACAATCCGA
ACAAGGAGGAGGTTCCCCCA

Downstream 100 bases:

>100_bases
GATTTGCCCCGATTTTTTGTCCAACCTGAACAAATTAACAGCGATACAGCCGTCATTAATGGGCCGGATGTAAAACATAT
CAGCCGGGTTTTGAGGATGG

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNWLEIAVHVCPEGIDMVSNIFDELGAGGVVIEDPALINRYIEANIWDHYEFPPEVLNRPQPIVKAYLPEGPNLENKLVL
LQERLTGLPLDAVPTFERRQVAEEDWATAWMKYYKPVEIGQKLAVKPSWEDYVPEDGRIVLEMDPGMAFGCGNHPTTTMC
MEYLEGIIQGGESVADVGTGTGILAITSAKLGAARVLAVDLDEVAVKVSQENVERNGVQDIVEVFHGNLLDKVESKVDVV
IANIVANVIMILAPDVPRILKHGGYFITSGIIQFRAEEVRQKLEQTGFKILGRKEDGEWVSYLCILEG

Sequences:

>Translated_308_residues
MNWLEIAVHVCPEGIDMVSNIFDELGAGGVVIEDPALINRYIEANIWDHYEFPPEVLNRPQPIVKAYLPEGPNLENKLVL
LQERLTGLPLDAVPTFERRQVAEEDWATAWMKYYKPVEIGQKLAVKPSWEDYVPEDGRIVLEMDPGMAFGCGNHPTTTMC
MEYLEGIIQGGESVADVGTGTGILAITSAKLGAARVLAVDLDEVAVKVSQENVERNGVQDIVEVFHGNLLDKVESKVDVV
IANIVANVIMILAPDVPRILKHGGYFITSGIIQFRAEEVRQKLEQTGFKILGRKEDGEWVSYLCILEG
>Mature_308_residues
MNWLEIAVHVCPEGIDMVSNIFDELGAGGVVIEDPALINRYIEANIWDHYEFPPEVLNRPQPIVKAYLPEGPNLENKLVL
LQERLTGLPLDAVPTFERRQVAEEDWATAWMKYYKPVEIGQKLAVKPSWEDYVPEDGRIVLEMDPGMAFGCGNHPTTTMC
MEYLEGIIQGGESVADVGTGTGILAITSAKLGAARVLAVDLDEVAVKVSQENVERNGVQDIVEVFHGNLLDKVESKVDVV
IANIVANVIMILAPDVPRILKHGGYFITSGIIQFRAEEVRQKLEQTGFKILGRKEDGEWVSYLCILEG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=156, Percent_Identity=42.9487179487179, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_DESRM (A4J7F1)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113829.1
- ProteinModelPortal:   A4J7F1
- SMR:   A4J7F1
- STRING:   A4J7F1
- GeneID:   4957746
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2494
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- PhylomeDB:   A4J7F1
- ProtClustDB:   PRK00517
- BioCyc:   DRED349161:DRED_2494-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34141; Mature: 34141

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLEIAVHVCPEGIDMVSNIFDELGAGGVVIEDPALINRYIEANIWDHYEFPPEVLNRP
CCHHHEEEHHCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCCCHHHHCCC
QPIVKAYLPEGPNLENKLVLLQERLTGLPLDAVPTFERRQVAEEDWATAWMKYYKPVEIG
CHHHHHCCCCCCCCCHHHEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
QKLAVKPSWEDYVPEDGRIVLEMDPGMAFGCGNHPTTTMCMEYLEGIIQGGESVADVGTG
CEEECCCCCHHCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHCCCC
TGILAITSAKLGAARVLAVDLDEVAVKVSQENVERNGVQDIVEVFHGNLLDKVESKVDVV
CCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHH
IANIVANVIMILAPDVPRILKHGGYFITSGIIQFRAEEVRQKLEQTGFKILGRKEDGEWV
HHHHHHHHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
SYLCILEG
EEEEEECC
>Mature Secondary Structure
MNWLEIAVHVCPEGIDMVSNIFDELGAGGVVIEDPALINRYIEANIWDHYEFPPEVLNRP
CCHHHEEEHHCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCCCHHHHCCC
QPIVKAYLPEGPNLENKLVLLQERLTGLPLDAVPTFERRQVAEEDWATAWMKYYKPVEIG
CHHHHHCCCCCCCCCHHHEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
QKLAVKPSWEDYVPEDGRIVLEMDPGMAFGCGNHPTTTMCMEYLEGIIQGGESVADVGTG
CEEECCCCCHHCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHCCCC
TGILAITSAKLGAARVLAVDLDEVAVKVSQENVERNGVQDIVEVFHGNLLDKVESKVDVV
CCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHH
IANIVANVIMILAPDVPRILKHGGYFITSGIIQFRAEEVRQKLEQTGFKILGRKEDGEWV
HHHHHHHHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
SYLCILEG
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA