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The map label for this gene is cdd [H]

Identifier: 134300319

GI number: 134300319

Start: 2701984

End: 2702412

Strand: Reverse

Name: cdd [H]

Synonym: Dred_2480

Alternate gene names: 134300319

Gene position: 2702412-2701984 (Counterclockwise)

Preceding gene: 134300320

Following gene: 134300318

Centisome position: 74.9

GC content: 49.42

Gene sequence:

>429_bases
ATGACAATCTCGGCGGAGAAACTGATAGAGATGGCTAAAGAAGCCAGAGAAAAGGCCTATGTTCCTTACTCAAAATTTAA
GGTTGGTGCAGCCCTATTGACCCAGGAGGGGAAGGTTTTTACCGGTTGTAATGTTGAAAATGCATCCTTTGGACTGACCT
GCTGTGCAGAAAGAACAGCTATCTTTAAGGCTGTTTCGGAGGGTAATAGGGAATTTGTTGCCCTGGCGGTAATAGCCGAT
GTGCCAACCCTCTGTAGCCCCTGTGGCGCTTGCCGGCAGGTTATGGCAGAATTTGCCGGTGATATGAAGGTGCATATGGC
AAACCTGCATGGCCAGTACAAGACGATCACAGTAAGCGAACTGTTACCAGGGTATTTTACTGCGGAAGATATGGAGGCTC
AAGGGACGGGTAGCGGGGTCCAGCCATGA

Upstream 100 bases:

>100_bases
GTCTAGCCATTAATCCTTAGCAATTTGCTAAACCCAAAAGCTAAAGACTAAAGGCTTACCCCAAAGAAATGCGGTATAAG
ACGAAGGAAGGACTGATTAA

Downstream 100 bases:

>100_bases
GTTATGAGCTATGGGCTATGAGCTGAAAGCTAAAAGCTCAAGGCCCAAGGCTCACAGCCGACCCCAAAGACATACCCATA
AGCACCAAAAGCAACAAGGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTISAEKLIEMAKEAREKAYVPYSKFKVGAALLTQEGKVFTGCNVENASFGLTCCAERTAIFKAVSEGNREFVALAVIAD
VPTLCSPCGACRQVMAEFAGDMKVHMANLHGQYKTITVSELLPGYFTAEDMEAQGTGSGVQP

Sequences:

>Translated_142_residues
MTISAEKLIEMAKEAREKAYVPYSKFKVGAALLTQEGKVFTGCNVENASFGLTCCAERTAIFKAVSEGNREFVALAVIAD
VPTLCSPCGACRQVMAEFAGDMKVHMANLHGQYKTITVSELLPGYFTAEDMEAQGTGSGVQP
>Mature_141_residues
TISAEKLIEMAKEAREKAYVPYSKFKVGAALLTQEGKVFTGCNVENASFGLTCCAERTAIFKAVSEGNREFVALAVIADV
PTLCSPCGACRQVMAEFAGDMKVHMANLHGQYKTITVSELLPGYFTAEDMEAQGTGSGVQP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=128, Percent_Identity=53.90625, Blast_Score=142, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17540514, Length=131, Percent_Identity=48.8549618320611, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=45.3125, Blast_Score=109, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323274, Length=125, Percent_Identity=41.6, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24582741, Length=130, Percent_Identity=45.3846153846154, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI19920920, Length=107, Percent_Identity=55.1401869158878, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=46.6019417475728, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 15196; Mature: 15064

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISAEKLIEMAKEAREKAYVPYSKFKVGAALLTQEGKVFTGCNVENASFGLTCCAERTA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEHHHHHHH
IFKAVSEGNREFVALAVIADVPTLCSPCGACRQVMAEFAGDMKVHMANLHGQYKTITVSE
HHHHHHCCCCEEEEEEEECCCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHH
LLPGYFTAEDMEAQGTGSGVQP
HCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TISAEKLIEMAKEAREKAYVPYSKFKVGAALLTQEGKVFTGCNVENASFGLTCCAERTA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEHHHHHHH
IFKAVSEGNREFVALAVIADVPTLCSPCGACRQVMAEFAGDMKVHMANLHGQYKTITVSE
HHHHHHCCCCEEEEEEEECCCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHH
LLPGYFTAEDMEAQGTGSGVQP
HCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]