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The map label for this gene is cheC [H]

Identifier: 134300222

GI number: 134300222

Start: 2606599

End: 2607216

Strand: Reverse

Name: cheC [H]

Synonym: Dred_2383

Alternate gene names: 134300222

Gene position: 2607216-2606599 (Counterclockwise)

Preceding gene: 134300223

Following gene: 134300221

Centisome position: 72.26

GC content: 41.26

Gene sequence:

>618_bases
ATGACCGAAAACCAGGCTTTAACTGAAAGTCATCTTGATGTTCTCAAAGAAATAGGAAATATAGGTCTGGGAAATGCGGC
TACCGCCCTGGCTACTATGGTAAATAAACGGATTGACATGGCTGTTCCCCAGAGTAAATTCCTTGCTTTGGATGAAGTTA
TGGATCTAATGGGTGGCTTGGAGGAAGTTGTAAGTTGCGTTAGCCTACGGTTAGAGGGGGATGTCCCAGGACAGATTCTA
TTCCTTTTTAACCTTGAAAGTACTTTTAATCTGGTGGATATGTTGATGGGTATGGAGCAAGGTACAACGAAAGAACTGGA
TGAGATGGGAGAGTCCGTCGTTAAAGAAATTGGCAACGTTTTAACAGGTTCCTTTCTTAGTGCCATTGGTACCTTGACAG
GATTAAATATGATTCCTACTGTCCCTATGTTTGCAACGGATATGCTGGGGGCTGTGTTAAGTACATCACTGATAGCTGGT
GGCTATGTTGAAGAACATATTCTAATGATTGAGACGTTGCTATTCGAAGACCAGGAGAAAATTAGGGGACATTTCTTTAT
GATAACAGAGCAAGGTTCTTTGCAAACATTATTTGGTTCACTAGGCATGACAATTTAA

Upstream 100 bases:

>100_bases
ACGATTTTTAATTATGCGGAAATTGGTTTTGAAAAGGTTTCTCCATGTTTTTATCGAAAGAAATAATTAGCTAAACAGGT
GGCTGAAAGGATGGGATGAA

Downstream 100 bases:

>100_bases
TTTTAGGAGGAGTAGTAAACATGGGTAAGCGTATTTTGATTGTGGATGATGCAGCATTTATGCGGATGATGATTAAAAAT
ATATTAACCAAGAATGGTTA

Product: MCP methylation inhibitor CheC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTENQALTESHLDVLKEIGNIGLGNAATALATMVNKRIDMAVPQSKFLALDEVMDLMGGLEEVVSCVSLRLEGDVPGQIL
FLFNLESTFNLVDMLMGMEQGTTKELDEMGESVVKEIGNVLTGSFLSAIGTLTGLNMIPTVPMFATDMLGAVLSTSLIAG
GYVEEHILMIETLLFEDQEKIRGHFFMITEQGSLQTLFGSLGMTI

Sequences:

>Translated_205_residues
MTENQALTESHLDVLKEIGNIGLGNAATALATMVNKRIDMAVPQSKFLALDEVMDLMGGLEEVVSCVSLRLEGDVPGQIL
FLFNLESTFNLVDMLMGMEQGTTKELDEMGESVVKEIGNVLTGSFLSAIGTLTGLNMIPTVPMFATDMLGAVLSTSLIAG
GYVEEHILMIETLLFEDQEKIRGHFFMITEQGSLQTLFGSLGMTI
>Mature_204_residues
TENQALTESHLDVLKEIGNIGLGNAATALATMVNKRIDMAVPQSKFLALDEVMDLMGGLEEVVSCVSLRLEGDVPGQILF
LFNLESTFNLVDMLMGMEQGTTKELDEMGESVVKEIGNVLTGSFLSAIGTLTGLNMIPTVPMFATDMLGAVLSTSLIAGG
YVEEHILMIETLLFEDQEKIRGHFFMITEQGSLQTLFGSLGMTI

Specific function: Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6% as active as FliY, which indicates that CheC may function after addition of an attractant to cope with increased levels

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CheC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597 [H]

Pfam domain/function: PF04509 CheC [H]

EC number: NA

Molecular weight: Translated: 22157; Mature: 22026

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENQALTESHLDVLKEIGNIGLGNAATALATMVNKRIDMAVPQSKFLALDEVMDLMGGL
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EEVVSCVSLRLEGDVPGQILFLFNLESTFNLVDMLMGMEQGTTKELDEMGESVVKEIGNV
HHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LTGSFLSAIGTLTGLNMIPTVPMFATDMLGAVLSTSLIAGGYVEEHILMIETLLFEDQEK
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
IRGHFFMITEQGSLQTLFGSLGMTI
HCCEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TENQALTESHLDVLKEIGNIGLGNAATALATMVNKRIDMAVPQSKFLALDEVMDLMGGL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EEVVSCVSLRLEGDVPGQILFLFNLESTFNLVDMLMGMEQGTTKELDEMGESVVKEIGNV
HHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LTGSFLSAIGTLTGLNMIPTVPMFATDMLGAVLSTSLIAGGYVEEHILMIETLLFEDQEK
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
IRGHFFMITEQGSLQTLFGSLGMTI
HCCEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2832368; 9384377 [H]