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The map label for this gene is mpg1 [H]

Identifier: 134300173

GI number: 134300173

Start: 2550720

End: 2553206

Strand: Reverse

Name: mpg1 [H]

Synonym: Dred_2334

Alternate gene names: 134300173

Gene position: 2553206-2550720 (Counterclockwise)

Preceding gene: 134300174

Following gene: 134300172

Centisome position: 70.76

GC content: 45.36

Gene sequence:

>2487_bases
ATGGGAAGGAGTGATATTATGAAGGCTATTATTATGGCTGGTGGCGAAGGTACCCGGTTAAGGCCATTAACCTGTGGTTT
GCCGAAACCCATGATGCCGGTATGTAATCGCCCAATGATGGAACATATATTGCATTTATTAAAAAAACACGGGGTACATG
ATATCGGGGTAACCTTGCAATACTTACCTGAAGCCATCCGAGGTTATTTTGGTAATGGAGCTGATTTTAATGTGCATATG
CGTTACTATGTGGAAGAAGTGCCCCTAGGAACTGCCGGCAGTGTCAAAAATGCTCAGAAATTCCTTGACGAAACCTTTAT
TGTGATCAGCGGTGATGCCCTTACAGATTTGGATTTAAGCCAGGCCCTGGAGTTTCATCGCAAGAAGGGTGCCATTGCCA
CATTGGTCTTAACGCCAGTTGATATTCCACTGGAGTATGGAGTTGTGATCACCAATGGTGATGGCCATATTACTCAATTT
CTGGAAAAACCCGGTTGGGGAGAAGTATTTAGCGATACGGTCAATACTGGCATTTACATTTTAGAGCCAGAAGTACTTAA
CTATTTTGAACCAGGCCAGAAGTTTGATTTTAGTAATGATTTATTTCCTATTTTGCTGAAGGAAAAGCAGCCCTTGTTTG
GAGTTTCCCTTTCTGGTTATTGGTGTGATATTGGGAATTTACAGCAATATGTCCAGGCACATCAGGATTGCTTAACGGGT
AAGGTTTCTGTATCGATACCTGGGGAGCAAGTGGCTCCGGGTGTTTGGGTAGGAGAAAATACGCAAATTCAAGCAGGGGC
CAAAATTATAGGTCCAGCATTAATTGGGCAAAATTGCAAAATAGGCGCGGCTGCTGTGTTAGGCACCTACTCTGTAATTG
GTAATAATTGTTTGATTGGAGACCAGTCAACCCTGAAAAGAAGTGTGTTGTGGGATGGTGTTTACCTAGGCAGCAGGGCT
GCTATTCGGGGAGCTGTGGTGGGCAGTGGTGTAAAGATTAACACCAATGCTTCGGTATATGAAGGTGCAGTAATTGGCAG
CGGCTCTATAATAAAAGAGCGCGCTCTGTTGAAGCCCGATGTCAAGCTATGGCCTGACAAAGTGGTGGAGTCTGGTGCAA
CCGTAGAAAGTAGCCTTGTTTGGGGAACAGCTAAGCCCAAAGGACTCTTTGGTATTGAAGGCATTACGGGTTTGAGCAAT
ATTGATATTACGCCTGAATTTTCCAGTCGGGTAGGGGCTGCCTTCGGTACCAATCTGCCGGTGGGTACAAGGGTTGGTAT
TTCCTGCGATCGTTTTGCAGCATCCCGCATGATTAAAGAGGCCCTGGCCTGTGGCTTACAGTCAACAGGCATCCAAGTGG
TGGATTTTTGTCAAGGAATTACTCCCATGCACCGTTACGCGGTGCAAGCCAGCAACTGTCAGGCAGGTATACACGTTCGC
ATAAGTTCTCAACGGGCTGATAAGGTTAATTTGCTTTTTACCAATGACAGGGGCGGCAATATATCCCGGGGACAGGAACG
GAAGGTTGAAAACACCCTAGCCAGAGAAGATGTTCGCCGGGTGGAGGTCCAACAAATTCTTCCTATTATCACTATGCCCC
AAGCGGCGGAAACCTATATTGAGCATTTAACTGGAGCGGTTAACACCACTGCATTAAAGAAGTCTGGTCAACAACTTGTA
TTATTGTATGACCTAGATAATCTAGACCATTTTGTCTCGGGAGCACTGTCCTCCCTGGGCATTTCCTTAGAGCGTTTTGC
GGCAGATCAGTCCACTGCGGAACCAAGGGATTGGCAATGGTACCAGCAATACCTGCAAGAGCTGGCCCATACAGTACAAA
ATAAAGGCAGAGCAGCCGGTGCTATTATCGACCCCAATGGTGACAGGCTTATCCTAGTAGATGGCCGAGGAAATGTAATA
AGTGATGATCTGTTAACAGCCCTAATTTCCCTTATTATTCTGAAAGAACAGGCTGGTCCTGTCATTGTGCCGATCACAGC
TCCCAGGGCCATCGAGGCATTGGCTAGGAAATATCAAGGAAGCGTAGTACGTACCAAAACCTCCCAACAAGACTTTATAA
ACAAGATTATCAATCACCAGGTCTCAAATAATGCGGCAACCCATCATTATCTAATGAATTTTGATGCCTTGCTTGCATTG
CTAAAGGTACTTGAGTTTTGTGCCTGCAAAGATATAACCTTGGAAGAATTAATCAAGGAGATCCCAAACACTTTTTTAAA
TCAAGTCAAAGTGGAGGTTCCCTGGGAAGACAAGGGCAGGGTTATCCGGCGGCTCATTGAGGAGCAAGACAATGACATGG
AACTACTGGATGGGGTAAAGGTCTATCATACTAACGGTTGGGCTCTGGTATTACCAGACCCGGAGGAACCGGTATGCCGG
ATTTTCACAGAAGGGGATTCCATGGAAATTGCAGAGGAGTTAACCCATTTTTATACCGATAAAATAAAACAAATTATTGC
AACCTAG

Upstream 100 bases:

>100_bases
GTATATCAGGAGATCATTGATGCGGACCAAAAAGCTCCCTGGAAAAAAGAAAAATTAATAGGCAAGGTTGTTCGGACAGT
GGCCCACTAAGGGATAGAGC

Downstream 100 bases:

>100_bases
CCCTAGGGCTAGGTTGCAATTTTAGCTGATAACTTACAGAACAACAGACCACCCACAAGGAATTTTCTAAGCTATGTCGA
AAGTTATGTTCATTAGTTCG

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 828; Mature: 827

Protein sequence:

>828_residues
MGRSDIMKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEAIRGYFGNGADFNVHM
RYYVEEVPLGTAGSVKNAQKFLDETFIVISGDALTDLDLSQALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQF
LEKPGWGEVFSDTVNTGIYILEPEVLNYFEPGQKFDFSNDLFPILLKEKQPLFGVSLSGYWCDIGNLQQYVQAHQDCLTG
KVSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTYSVIGNNCLIGDQSTLKRSVLWDGVYLGSRA
AIRGAVVGSGVKINTNASVYEGAVIGSGSIIKERALLKPDVKLWPDKVVESGATVESSLVWGTAKPKGLFGIEGITGLSN
IDITPEFSSRVGAAFGTNLPVGTRVGISCDRFAASRMIKEALACGLQSTGIQVVDFCQGITPMHRYAVQASNCQAGIHVR
ISSQRADKVNLLFTNDRGGNISRGQERKVENTLAREDVRRVEVQQILPIITMPQAAETYIEHLTGAVNTTALKKSGQQLV
LLYDLDNLDHFVSGALSSLGISLERFAADQSTAEPRDWQWYQQYLQELAHTVQNKGRAAGAIIDPNGDRLILVDGRGNVI
SDDLLTALISLIILKEQAGPVIVPITAPRAIEALARKYQGSVVRTKTSQQDFINKIINHQVSNNAATHHYLMNFDALLAL
LKVLEFCACKDITLEELIKEIPNTFLNQVKVEVPWEDKGRVIRRLIEEQDNDMELLDGVKVYHTNGWALVLPDPEEPVCR
IFTEGDSMEIAEELTHFYTDKIKQIIAT

Sequences:

>Translated_828_residues
MGRSDIMKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEAIRGYFGNGADFNVHM
RYYVEEVPLGTAGSVKNAQKFLDETFIVISGDALTDLDLSQALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQF
LEKPGWGEVFSDTVNTGIYILEPEVLNYFEPGQKFDFSNDLFPILLKEKQPLFGVSLSGYWCDIGNLQQYVQAHQDCLTG
KVSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTYSVIGNNCLIGDQSTLKRSVLWDGVYLGSRA
AIRGAVVGSGVKINTNASVYEGAVIGSGSIIKERALLKPDVKLWPDKVVESGATVESSLVWGTAKPKGLFGIEGITGLSN
IDITPEFSSRVGAAFGTNLPVGTRVGISCDRFAASRMIKEALACGLQSTGIQVVDFCQGITPMHRYAVQASNCQAGIHVR
ISSQRADKVNLLFTNDRGGNISRGQERKVENTLAREDVRRVEVQQILPIITMPQAAETYIEHLTGAVNTTALKKSGQQLV
LLYDLDNLDHFVSGALSSLGISLERFAADQSTAEPRDWQWYQQYLQELAHTVQNKGRAAGAIIDPNGDRLILVDGRGNVI
SDDLLTALISLIILKEQAGPVIVPITAPRAIEALARKYQGSVVRTKTSQQDFINKIINHQVSNNAATHHYLMNFDALLAL
LKVLEFCACKDITLEELIKEIPNTFLNQVKVEVPWEDKGRVIRRLIEEQDNDMELLDGVKVYHTNGWALVLPDPEEPVCR
IFTEGDSMEIAEELTHFYTDKIKQIIAT
>Mature_827_residues
GRSDIMKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEAIRGYFGNGADFNVHMR
YYVEEVPLGTAGSVKNAQKFLDETFIVISGDALTDLDLSQALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFL
EKPGWGEVFSDTVNTGIYILEPEVLNYFEPGQKFDFSNDLFPILLKEKQPLFGVSLSGYWCDIGNLQQYVQAHQDCLTGK
VSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTYSVIGNNCLIGDQSTLKRSVLWDGVYLGSRAA
IRGAVVGSGVKINTNASVYEGAVIGSGSIIKERALLKPDVKLWPDKVVESGATVESSLVWGTAKPKGLFGIEGITGLSNI
DITPEFSSRVGAAFGTNLPVGTRVGISCDRFAASRMIKEALACGLQSTGIQVVDFCQGITPMHRYAVQASNCQAGIHVRI
SSQRADKVNLLFTNDRGGNISRGQERKVENTLAREDVRRVEVQQILPIITMPQAAETYIEHLTGAVNTTALKKSGQQLVL
LYDLDNLDHFVSGALSSLGISLERFAADQSTAEPRDWQWYQQYLQELAHTVQNKGRAAGAIIDPNGDRLILVDGRGNVIS
DDLLTALISLIILKEQAGPVIVPITAPRAIEALARKYQGSVVRTKTSQQDFINKIINHQVSNNAATHHYLMNFDALLALL
KVLEFCACKDITLEELIKEIPNTFLNQVKVEVPWEDKGRVIRRLIEEQDNDMELLDGVKVYHTNGWALVLPDPEEPVCRI
FTEGDSMEIAEELTHFYTDKIKQIIAT

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=357, Percent_Identity=30.2521008403361, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI11761619, Length=342, Percent_Identity=31.2865497076023, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI31881779, Length=373, Percent_Identity=26.8096514745308, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI45447090, Length=373, Percent_Identity=26.8096514745308, Blast_Score=117, Evalue=6e-26,
Organism=Escherichia coli, GI1788351, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1789837, Length=393, Percent_Identity=23.9185750636132, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790224, Length=188, Percent_Identity=29.2553191489362, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=359, Percent_Identity=30.6406685236769, Blast_Score=159, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17509979, Length=337, Percent_Identity=23.7388724035608, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509981, Length=324, Percent_Identity=23.1481481481481, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320148, Length=328, Percent_Identity=34.1463414634146, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6320417, Length=428, Percent_Identity=23.3644859813084, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355443, Length=352, Percent_Identity=30.1136363636364, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24644084, Length=352, Percent_Identity=30.1136363636364, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24653912, Length=380, Percent_Identity=23.4210526315789, Blast_Score=88, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 90563; Mature: 90432

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRSDIMKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQ
CCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
YLPEAIRGYFGNGADFNVHMRYYVEEVPLGTAGSVKNAQKFLDETFIVISGDALTDLDLS
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCHH
QALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFLEKPGWGEVFSDTVNTGIYI
HHHHHHHHCCCEEEEEEECCCCCEECCEEEECCCCHHHHHHHCCCCCHHHHHHHCCCEEE
LEPEVLNYFEPGQKFDFSNDLFPILLKEKQPLFGVSLSGYWCDIGNLQQYVQAHQDCLTG
ECHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC
KVSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTYSVIGNNCLIG
EEEEECCCHHCCCCEEECCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEC
DQSTLKRSVLWDGVYLGSRAAIRGAVVGSGVKINTNASVYEGAVIGSGSIIKERALLKPD
CHHHHHHHHHHCCEEECCCHHHHHEEECCCEEECCCCCEECCEEECCCCHHHHHHHCCCC
VKLWPDKVVESGATVESSLVWGTAKPKGLFGIEGITGLSNIDITPEFSSRVGAAFGTNLP
CCCCCHHHHHCCCCEECCEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHCCHHHCCCCC
VGTRVGISCDRFAASRMIKEALACGLQSTGIQVVDFCQGITPMHRYAVQASNCQAGIHVR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHEECCCCCCEEEEE
ISSQRADKVNLLFTNDRGGNISRGQERKVENTLAREDVRRVEVQQILPIITMPQAAETYI
EECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHH
EHLTGAVNTTALKKSGQQLVLLYDLDNLDHFVSGALSSLGISLERFAADQSTAEPRDWQW
HHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHH
YQQYLQELAHTVQNKGRAAGAIIDPNGDRLILVDGRGNVISDDLLTALISLIILKEQAGP
HHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCC
VIVPITAPRAIEALARKYQGSVVRTKTSQQDFINKIINHQVSNNAATHHYLMNFDALLAL
EEEEECCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKVLEFCACKDITLEELIKEIPNTFLNQVKVEVPWEDKGRVIRRLIEEQDNDMELLDGVK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCHHHHCCEE
VYHTNGWALVLPDPEEPVCRIFTEGDSMEIAEELTHFYTDKIKQIIAT
EEEECCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRSDIMKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQ
CHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
YLPEAIRGYFGNGADFNVHMRYYVEEVPLGTAGSVKNAQKFLDETFIVISGDALTDLDLS
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCHH
QALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFLEKPGWGEVFSDTVNTGIYI
HHHHHHHHCCCEEEEEEECCCCCEECCEEEECCCCHHHHHHHCCCCCHHHHHHHCCCEEE
LEPEVLNYFEPGQKFDFSNDLFPILLKEKQPLFGVSLSGYWCDIGNLQQYVQAHQDCLTG
ECHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC
KVSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTYSVIGNNCLIG
EEEEECCCHHCCCCEEECCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEC
DQSTLKRSVLWDGVYLGSRAAIRGAVVGSGVKINTNASVYEGAVIGSGSIIKERALLKPD
CHHHHHHHHHHCCEEECCCHHHHHEEECCCEEECCCCCEECCEEECCCCHHHHHHHCCCC
VKLWPDKVVESGATVESSLVWGTAKPKGLFGIEGITGLSNIDITPEFSSRVGAAFGTNLP
CCCCCHHHHHCCCCEECCEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHCCHHHCCCCC
VGTRVGISCDRFAASRMIKEALACGLQSTGIQVVDFCQGITPMHRYAVQASNCQAGIHVR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHEECCCCCCEEEEE
ISSQRADKVNLLFTNDRGGNISRGQERKVENTLAREDVRRVEVQQILPIITMPQAAETYI
EECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHH
EHLTGAVNTTALKKSGQQLVLLYDLDNLDHFVSGALSSLGISLERFAADQSTAEPRDWQW
HHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHH
YQQYLQELAHTVQNKGRAAGAIIDPNGDRLILVDGRGNVISDDLLTALISLIILKEQAGP
HHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCC
VIVPITAPRAIEALARKYQGSVVRTKTSQQDFINKIINHQVSNNAATHHYLMNFDALLAL
EEEEECCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKVLEFCACKDITLEELIKEIPNTFLNQVKVEVPWEDKGRVIRRLIEEQDNDMELLDGVK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCHHHHCCEE
VYHTNGWALVLPDPEEPVCRIFTEGDSMEIAEELTHFYTDKIKQIIAT
EEEECCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]