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The map label for this gene is pbuG [H]

Identifier: 134300141

GI number: 134300141

Start: 2516472

End: 2517767

Strand: Reverse

Name: pbuG [H]

Synonym: Dred_2302

Alternate gene names: 134300141

Gene position: 2517767-2516472 (Counterclockwise)

Preceding gene: 134300142

Following gene: 134300139

Centisome position: 69.78

GC content: 41.9

Gene sequence:

>1296_bases
ATGAGAAAATATTTTGGCTTTGATGAGTATGGTATATCCTACAGAACGGAATTTATTGGTGGAATGACAACTTTCTTATC
CATGTGTTATATTTTAGTGGCTAATCCGATGATCCTTGGGGAGGCAGGAATGGATAAGGGTGCGGTATTTACAGCAACGG
CCCTTTCCGCCATCATAGGAACCCTGGTTATGGGTGTGCTGGCCAATTACCCCTTGGCACTGGCACCAAGTCTTGGCCTA
AATTCATTTTTTACCTACTCAGTGGTTATAGGTATGGGCGTAGCCTGGGAAACTGCCCTGGCTGGGGTGCTGGTTTCAGG
GCTTGTATTCATGGCTATTACTGCCTTTAAAATTCGGGAAAAGATTATTGATGCGATTCCTGAGGAGTTAAAGTATGCCA
TTGCTGGAGGAATTGGTTTTTTTATTGCCTTTATAGGTTTAAAAAATGCAGGAATAATAGTAAGCCATAAGGCAACCTAC
GTTTCCCTGGGGAATTTACAAGAACCTTCAACACTTCTTGCCCTTTTTGGTTTTATCATTACCGTGGTGTTTATTGTTAA
GGGTTGGCAGGGAGGCATTTTCTATGGTATGGTTGTTACCACCATTGTTGGTATGGTAGCGGGAATTATTGATAAACCAG
TTGCTATCATAGGTGGCATTCCCAGCTTAGAACCTACCTTTGGGGTTGCCTTTAGTCATATACCGGATGTTTTTAATTAT
GATATGCTATTAGTGATTTTTACATTTTTATTTGTCAGCTTCTTTGATGCTTCCGGAACCTTGATTGCCGTGGCTAATCA
GGCGGGTATTATGAAAAACAATAAGATTCCAAGGGTTAGTCAAGCCCTTATGGCAGATGCCTCTGCGTCAGTTGTTGGAG
CAACCTTTGGTACATCCACTGTAACGGCATTAATTGAATCCTCTGCTGGGATTGCAGTGGGGGCCAGAACCGGGTTTTCT
TCCATTGTAGTAGCAGCGTTTTTCTTTTTAGCACTGTTTTTCTCGCCGTTATTATCAGTTATCACAACTCCGGTTACGGC
GCCGGCCCTCATCATTGTAGGTTCCATGATGGCCAGTCAAATTAATAAGATTAAATGGCAGCAATTCGATGTGGCACTGC
CGGCCTTTATTACCATCATTATGATGCCCTTAACCTTCAGTGTGGCAACAGGCATTGCCTTAGGTTTTATTATGTACCCC
ATCATTAAACTGGCCATGAGAAAGTACCAGGAAATTCACCCCATCATGTATGGGTTAATGTTTATCTTTATGTTGTACTT
TTACTATATTAATTAA

Upstream 100 bases:

>100_bases
ACATTATACTTAAAGGTCAAGGCTCTAGTATTTTGGTTTATACCAATTATTAGAGTTTTTTTATTGAGACATAAAATTTT
AACAGCTGGGGGCAAGGACT

Downstream 100 bases:

>100_bases
GTCCTTTTATCTAAGGTGACTAGAAAAAACGGAACCACTGCTTGTTTTAAGCAGTGGTTCTAGCTGTAGAGAAATTTCTT
TGCTTGTATTTGTTTTATTT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRKYFGFDEYGISYRTEFIGGMTTFLSMCYILVANPMILGEAGMDKGAVFTATALSAIIGTLVMGVLANYPLALAPSLGL
NSFFTYSVVIGMGVAWETALAGVLVSGLVFMAITAFKIREKIIDAIPEELKYAIAGGIGFFIAFIGLKNAGIIVSHKATY
VSLGNLQEPSTLLALFGFIITVVFIVKGWQGGIFYGMVVTTIVGMVAGIIDKPVAIIGGIPSLEPTFGVAFSHIPDVFNY
DMLLVIFTFLFVSFFDASGTLIAVANQAGIMKNNKIPRVSQALMADASASVVGATFGTSTVTALIESSAGIAVGARTGFS
SIVVAAFFFLALFFSPLLSVITTPVTAPALIIVGSMMASQINKIKWQQFDVALPAFITIIMMPLTFSVATGIALGFIMYP
IIKLAMRKYQEIHPIMYGLMFIFMLYFYYIN

Sequences:

>Translated_431_residues
MRKYFGFDEYGISYRTEFIGGMTTFLSMCYILVANPMILGEAGMDKGAVFTATALSAIIGTLVMGVLANYPLALAPSLGL
NSFFTYSVVIGMGVAWETALAGVLVSGLVFMAITAFKIREKIIDAIPEELKYAIAGGIGFFIAFIGLKNAGIIVSHKATY
VSLGNLQEPSTLLALFGFIITVVFIVKGWQGGIFYGMVVTTIVGMVAGIIDKPVAIIGGIPSLEPTFGVAFSHIPDVFNY
DMLLVIFTFLFVSFFDASGTLIAVANQAGIMKNNKIPRVSQALMADASASVVGATFGTSTVTALIESSAGIAVGARTGFS
SIVVAAFFFLALFFSPLLSVITTPVTAPALIIVGSMMASQINKIKWQQFDVALPAFITIIMMPLTFSVATGIALGFIMYP
IIKLAMRKYQEIHPIMYGLMFIFMLYFYYIN
>Mature_431_residues
MRKYFGFDEYGISYRTEFIGGMTTFLSMCYILVANPMILGEAGMDKGAVFTATALSAIIGTLVMGVLANYPLALAPSLGL
NSFFTYSVVIGMGVAWETALAGVLVSGLVFMAITAFKIREKIIDAIPEELKYAIAGGIGFFIAFIGLKNAGIIVSHKATY
VSLGNLQEPSTLLALFGFIITVVFIVKGWQGGIFYGMVVTTIVGMVAGIIDKPVAIIGGIPSLEPTFGVAFSHIPDVFNY
DMLLVIFTFLFVSFFDASGTLIAVANQAGIMKNNKIPRVSQALMADASASVVGATFGTSTVTALIESSAGIAVGARTGFS
SIVVAAFFFLALFFSPLLSVITTPVTAPALIIVGSMMASQINKIKWQQFDVALPAFITIIMMPLTFSVATGIALGFIMYP
IIKLAMRKYQEIHPIMYGLMFIFMLYFYYIN

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=416, Percent_Identity=40.8653846153846, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1790150, Length=434, Percent_Identity=41.0138248847926, Blast_Score=320, Evalue=9e-89,
Organism=Escherichia coli, GI1790499, Length=421, Percent_Identity=32.0665083135392, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI48994909, Length=423, Percent_Identity=31.6784869976359, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46214; Mature: 46214

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKYFGFDEYGISYRTEFIGGMTTFLSMCYILVANPMILGEAGMDKGAVFTATALSAIIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHH
TLVMGVLANYPLALAPSLGLNSFFTYSVVIGMGVAWETALAGVLVSGLVFMAITAFKIRE
HHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIIDAIPEELKYAIAGGIGFFIAFIGLKNAGIIVSHKATYVSLGNLQEPSTLLALFGFII
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHH
TVVFIVKGWQGGIFYGMVVTTIVGMVAGIIDKPVAIIGGIPSLEPTFGVAFSHIPDVFNY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHCCHHHCH
DMLLVIFTFLFVSFFDASGTLIAVANQAGIMKNNKIPRVSQALMADASASVVGATFGTST
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCHHH
VTALIESSAGIAVGARTGFSSIVVAAFFFLALFFSPLLSVITTPVTAPALIIVGSMMASQ
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
INKIKWQQFDVALPAFITIIMMPLTFSVATGIALGFIMYPIIKLAMRKYQEIHPIMYGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFMLYFYYIN
HHHHHHHHHCC
>Mature Secondary Structure
MRKYFGFDEYGISYRTEFIGGMTTFLSMCYILVANPMILGEAGMDKGAVFTATALSAIIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHH
TLVMGVLANYPLALAPSLGLNSFFTYSVVIGMGVAWETALAGVLVSGLVFMAITAFKIRE
HHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIIDAIPEELKYAIAGGIGFFIAFIGLKNAGIIVSHKATYVSLGNLQEPSTLLALFGFII
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHH
TVVFIVKGWQGGIFYGMVVTTIVGMVAGIIDKPVAIIGGIPSLEPTFGVAFSHIPDVFNY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHCCHHHCH
DMLLVIFTFLFVSFFDASGTLIAVANQAGIMKNNKIPRVSQALMADASASVVGATFGTST
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCHHH
VTALIESSAGIAVGARTGFSSIVVAAFFFLALFFSPLLSVITTPVTAPALIIVGSMMASQ
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
INKIKWQQFDVALPAFITIIMMPLTFSVATGIALGFIMYPIIKLAMRKYQEIHPIMYGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFMLYFYYIN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]