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The map label for this gene is cobC [H]

Identifier: 134300127

GI number: 134300127

Start: 2501269

End: 2501736

Strand: Reverse

Name: cobC [H]

Synonym: Dred_2288

Alternate gene names: 134300127

Gene position: 2501736-2501269 (Counterclockwise)

Preceding gene: 134300128

Following gene: 134300126

Centisome position: 69.34

GC content: 42.09

Gene sequence:

>468_bases
TTGAACTCTATTTTTTGCAGTGATTTACAGCGTTCACGACAAATGGCTGAAATAATTGCAGAAAAGCATAATCTAAGGCC
AACTGTCAGCCTGAGCCTAAGGGAAATTTACCTGGGGGAGTGGGAAGGGCGATACTTTGAAGAAATCCGCCGCAAATTTC
CCCAGGATTTTATGCAAAGGGGAAAAGACATAGCTAACTTCTGTCCACCCGGCGGAGAAAGTTTTAGTCAGTGCAGCCAA
AGGGTATTGGCTAAGTTAGATGAATTAATGCAAAGAACCACCGGCAATATTTTAATTGCCGGTCATGCAGGGGTAAACCG
TGTGCTTCTTTGTCATATGCTGGGTATGCCACTGGAAAACCTTTTTCGTATTAGTCAAGACTATGGTTGTCTCAACATCA
TTGGTTATGAGAAGGGTAAATATAGAATTAAGCTTTTGAACAGGCAATTCAGGATCGTCACCCTTTAA

Upstream 100 bases:

>100_bases
AAAGGGTGGAAAAAGATTTATCGGTCAGCTTGATCTGCCTCTCAGTGAATTAGGTATCAATCAAGCCAATCGTCTAAAGG
AGGAGCTTAGCTGTGTTCGC

Downstream 100 bases:

>100_bases
AGGATGAGTAAGCATCTTTGATACCGCTGCCCTTGGCAGTGGTTTTGTTTTTTGTCAAAATCATAATAAGGATTTTTTGT
TAAGTAATTTCAACAACAAT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MNSIFCSDLQRSRQMAEIIAEKHNLRPTVSLSLREIYLGEWEGRYFEEIRRKFPQDFMQRGKDIANFCPPGGESFSQCSQ
RVLAKLDELMQRTTGNILIAGHAGVNRVLLCHMLGMPLENLFRISQDYGCLNIIGYEKGKYRIKLLNRQFRIVTL

Sequences:

>Translated_155_residues
MNSIFCSDLQRSRQMAEIIAEKHNLRPTVSLSLREIYLGEWEGRYFEEIRRKFPQDFMQRGKDIANFCPPGGESFSQCSQ
RVLAKLDELMQRTTGNILIAGHAGVNRVLLCHMLGMPLENLFRISQDYGCLNIIGYEKGKYRIKLLNRQFRIVTL
>Mature_155_residues
MNSIFCSDLQRSRQMAEIIAEKHNLRPTVSLSLREIYLGEWEGRYFEEIRRKFPQDFMQRGKDIANFCPPGGESFSQCSQ
RVLAKLDELMQRTTGNILIAGHAGVNRVLLCHMLGMPLENLFRISQDYGCLNIIGYEKGKYRIKLLNRQFRIVTL

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=147, Percent_Identity=27.891156462585, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 18002; Mature: 18002

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIFCSDLQRSRQMAEIIAEKHNLRPTVSLSLREIYLGEWEGRYFEEIRRKFPQDFMQR
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHC
GKDIANFCPPGGESFSQCSQRVLAKLDELMQRTTGNILIAGHAGVNRVLLCHMLGMPLEN
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHH
LFRISQDYGCLNIIGYEKGKYRIKLLNRQFRIVTL
HHHHHCCCCEEEEEECCCCCEEEEEECCEEEEEEC
>Mature Secondary Structure
MNSIFCSDLQRSRQMAEIIAEKHNLRPTVSLSLREIYLGEWEGRYFEEIRRKFPQDFMQR
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHC
GKDIANFCPPGGESFSQCSQRVLAKLDELMQRTTGNILIAGHAGVNRVLLCHMLGMPLEN
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHH
LFRISQDYGCLNIIGYEKGKYRIKLLNRQFRIVTL
HHHHHCCCCEEEEEECCCCCEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]