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The map label for this gene is yfbK [H]

Identifier: 134300085

GI number: 134300085

Start: 2453286

End: 2454536

Strand: Reverse

Name: yfbK [H]

Synonym: Dred_2244

Alternate gene names: 134300085

Gene position: 2454536-2453286 (Counterclockwise)

Preceding gene: 134300086

Following gene: 134300084

Centisome position: 68.03

GC content: 46.6

Gene sequence:

>1251_bases
ATGGAACAAATTCAAATTGATCTTGCTCTAGATAAGACCTATCTGCTACCAGGTAATAAGCAGGTGGCCTATCTGATGGT
AAAGCTTACTGCGCCTAAGCAAGTGGAGAAGGAAAGGCCGGTGCAGAATCTGTCCTTTGTTATTGACCGCAGCGGCAGTA
TGGCAGGGGAAAAGCTAGACTACACCAAAAAGGCAGTTGCCTTTGCGGTTGGTCATCTAAGTCCACAGGATTACTGCTCG
GTAGTAGCCTTTGACGATATGGTAACGATGGTGGCCTCCTCTCACCAGGTGGCAAACAAAGATGCACTTAAGATGGCGGT
GGAAAGTATCTATCCCGGTGGCAGCACAAACCTAAGCGGCGGCATGCTGCTGGGCGTAAGGGAAGTAAAGCTGGCCCACA
AAGAGAATCAAATCAACCGGGTGCTGCTGCTAACAGATGGCATGGCCAATGTGGGAGTGACAGACCACAGTGCCCTGGTG
GAGAAGTCCCGGGAAATGGCTGCCGGTGGGGTTAATCTTTCTACCTTTGGTTTGGGGGAAGATTTTGAAGAAGATTTATT
GCAGGCAATGGTGGAGGCTGGGGGCGGTAACTTCTATTATATAGAAAAACCGGATCAAATACCTGGTATTTTTGAACAGG
AATTAACTGGGTTGCTAAGTATCGTGGCCCAAAATCTCTCAGTAAAAGTGAAACCGGGGCAAGGTGTGTCTATAACCGGA
GTGCTTGGTTATCCCTTTAGCTCCGAGGAAGGGGTTACTGTAAACCTGCCGGATATTTATAGTGGTGAATCAAAGCTATT
GCTACTGGAGTTGCTTATTTCGCCGCTGACGGAAGGTAATCACAAGCTCATCAGTGTAGAGTTGGATTATGCAGACGTTC
GAAAAAGCCTGGCGCTGGTGAATCTCAAGGCAGAGCTAAGTATAAATGCTAGTGCGGAAATAGGGGATGAACCTGCTGAA
AACATAGAGGTGATCAAGCAGGTGGAACTATTCCGCTGTGCTCAGGCTAAGGAAGAAGCTATTCGGTTAGCTGATCAGGG
AGACTTCCAGGCTAGTCGTCTTGTCTTGGAAAATCAGTTATATAAGCTACAGTCTTTGGGAGCTTGTTTAGATTCTAGTG
ATCTTAATATGGAAGTAAACGAATTACAGGAAAACCTTTGCTTTATGTCCGAGGGCAGTTATGATAAGGCCTCACGGAAG
AAAATGTCCTTTAACGCTTACCAACGGAAGAAAGGGAGAGGTAGAAAATAA

Upstream 100 bases:

>100_bases
TACAGTGCAACGGAAAAACAGTGGTTTTGCCCCTATTGTGGTTGTGATTTGACAAAGCAGCCCATTCAATCGATTAAAAA
GAAGGAGGAGGAAAAACCTA

Downstream 100 bases:

>100_bases
ATAGTAAAGGCTAGGAATCGTTTCATATCAAAATAATAGGGGGTAATAAGAATGTCTGAAAAGGAAAAGATTAAAAAGCC
TATCTATAAGAGGTGGTGGT

Product: von Willebrand factor, type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MEQIQIDLALDKTYLLPGNKQVAYLMVKLTAPKQVEKERPVQNLSFVIDRSGSMAGEKLDYTKKAVAFAVGHLSPQDYCS
VVAFDDMVTMVASSHQVANKDALKMAVESIYPGGSTNLSGGMLLGVREVKLAHKENQINRVLLLTDGMANVGVTDHSALV
EKSREMAAGGVNLSTFGLGEDFEEDLLQAMVEAGGGNFYYIEKPDQIPGIFEQELTGLLSIVAQNLSVKVKPGQGVSITG
VLGYPFSSEEGVTVNLPDIYSGESKLLLLELLISPLTEGNHKLISVELDYADVRKSLALVNLKAELSINASAEIGDEPAE
NIEVIKQVELFRCAQAKEEAIRLADQGDFQASRLVLENQLYKLQSLGACLDSSDLNMEVNELQENLCFMSEGSYDKASRK
KMSFNAYQRKKGRGRK

Sequences:

>Translated_416_residues
MEQIQIDLALDKTYLLPGNKQVAYLMVKLTAPKQVEKERPVQNLSFVIDRSGSMAGEKLDYTKKAVAFAVGHLSPQDYCS
VVAFDDMVTMVASSHQVANKDALKMAVESIYPGGSTNLSGGMLLGVREVKLAHKENQINRVLLLTDGMANVGVTDHSALV
EKSREMAAGGVNLSTFGLGEDFEEDLLQAMVEAGGGNFYYIEKPDQIPGIFEQELTGLLSIVAQNLSVKVKPGQGVSITG
VLGYPFSSEEGVTVNLPDIYSGESKLLLLELLISPLTEGNHKLISVELDYADVRKSLALVNLKAELSINASAEIGDEPAE
NIEVIKQVELFRCAQAKEEAIRLADQGDFQASRLVLENQLYKLQSLGACLDSSDLNMEVNELQENLCFMSEGSYDKASRK
KMSFNAYQRKKGRGRK
>Mature_416_residues
MEQIQIDLALDKTYLLPGNKQVAYLMVKLTAPKQVEKERPVQNLSFVIDRSGSMAGEKLDYTKKAVAFAVGHLSPQDYCS
VVAFDDMVTMVASSHQVANKDALKMAVESIYPGGSTNLSGGMLLGVREVKLAHKENQINRVLLLTDGMANVGVTDHSALV
EKSREMAAGGVNLSTFGLGEDFEEDLLQAMVEAGGGNFYYIEKPDQIPGIFEQELTGLLSIVAQNLSVKVKPGQGVSITG
VLGYPFSSEEGVTVNLPDIYSGESKLLLLELLISPLTEGNHKLISVELDYADVRKSLALVNLKAELSINASAEIGDEPAE
NIEVIKQVELFRCAQAKEEAIRLADQGDFQASRLVLENQLYKLQSLGACLDSSDLNMEVNELQENLCFMSEGSYDKASRK
KMSFNAYQRKKGRGRK

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To Synechocystis PCC 6803 sll0103 [H]

Homologues:

Organism=Homo sapiens, GI261878614, Length=240, Percent_Identity=30.8333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI133925809, Length=219, Percent_Identity=31.5068493150685, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI156119625, Length=240, Percent_Identity=30.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI49355778, Length=213, Percent_Identity=28.169014084507, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI153945780, Length=230, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI153945711, Length=230, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI261878618, Length=200, Percent_Identity=32.5, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI261878616, Length=200, Percent_Identity=32.5, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI31542984, Length=166, Percent_Identity=28.3132530120482, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI262050538, Length=166, Percent_Identity=28.3132530120482, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788606, Length=220, Percent_Identity=30.9090909090909, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021908
- InterPro:   IPR022156
- InterPro:   IPR002035 [H]

Pfam domain/function: PF12034 DUF3520; PF00092 VWA; PF12450 vWF_A [H]

EC number: NA

Molecular weight: Translated: 45424; Mature: 45424

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQIQIDLALDKTYLLPGNKQVAYLMVKLTAPKQVEKERPVQNLSFVIDRSGSMAGEKLD
CCEEEEEEEECCEEECCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCCHHH
YTKKAVAFAVGHLSPQDYCSVVAFDDMVTMVASSHQVANKDALKMAVESIYPGGSTNLSG
HHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCCCCCC
GMLLGVREVKLAHKENQINRVLLLTDGMANVGVTDHSALVEKSREMAAGGVNLSTFGLGE
CEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCC
DFEEDLLQAMVEAGGGNFYYIEKPDQIPGIFEQELTGLLSIVAQNLSVKVKPGQGVSITG
CHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
VLGYPFSSEEGVTVNLPDIYSGESKLLLLELLISPLTEGNHKLISVELDYADVRKSLALV
EEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHEEE
NLKAELSINASAEIGDEPAENIEVIKQVELFRCAQAKEEAIRLADQGDFQASRLVLENQL
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YKLQSLGACLDSSDLNMEVNELQENLCFMSEGSYDKASRKKMSFNAYQRKKGRGRK
HHHHHHHHHCCCCCCCEEHHHHHHHHEEECCCCCCHHHHHHHCHHHHHHCCCCCCC
>Mature Secondary Structure
MEQIQIDLALDKTYLLPGNKQVAYLMVKLTAPKQVEKERPVQNLSFVIDRSGSMAGEKLD
CCEEEEEEEECCEEECCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCCHHH
YTKKAVAFAVGHLSPQDYCSVVAFDDMVTMVASSHQVANKDALKMAVESIYPGGSTNLSG
HHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCCCCCC
GMLLGVREVKLAHKENQINRVLLLTDGMANVGVTDHSALVEKSREMAAGGVNLSTFGLGE
CEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCC
DFEEDLLQAMVEAGGGNFYYIEKPDQIPGIFEQELTGLLSIVAQNLSVKVKPGQGVSITG
CHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
VLGYPFSSEEGVTVNLPDIYSGESKLLLLELLISPLTEGNHKLISVELDYADVRKSLALV
EEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHEEE
NLKAELSINASAEIGDEPAENIEVIKQVELFRCAQAKEEAIRLADQGDFQASRLVLENQL
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YKLQSLGACLDSSDLNMEVNELQENLCFMSEGSYDKASRKKMSFNAYQRKKGRGRK
HHHHHHHHHCCCCCCCEEHHHHHHHHEEECCCCCCHHHHHHHCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]