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The map label for this gene is kamA [H]

Identifier: 134299994

GI number: 134299994

Start: 2352397

End: 2353665

Strand: Reverse

Name: kamA [H]

Synonym: Dred_2148

Alternate gene names: 134299994

Gene position: 2353665-2352397 (Counterclockwise)

Preceding gene: 134299995

Following gene: 134299993

Centisome position: 65.23

GC content: 39.09

Gene sequence:

>1269_bases
ATGTCTGTTCATTTAAAGCAAGAAGAGTTCCGGCTAAGACAAGAAAAACGAAAAATTGCTCTAAAAAGGGCAAAGGAGTT
AAAAGCTCGTATCACTGATTATCTTGAGAACAAGGATCAAATTAAAAATGGTTTTGAGGTGCAAGAACAGTACAATCGGG
CAAAACAAACTTTACTAAATTTTTTTAATGCAGATAATGAGCAGTGGGAAAATTGGCACTGGCAAATGGCAAATCGTATT
AAAGATGTTAAAGTAATAAGCCAGTTAATAGATCTTTCCCCGGCTGAAAAAGAGGCCATTGAAAAAGTGGGGCGCCAGTA
CCGTTGGGCGGTATCACCCTATTATATGGCTCTGGCAATGGTAAGTGGTTCCGGTGGCCCTGTTTGGTTACAGGCTATAC
CCTGTATAGAAGAAGTAAAGGATCGTTACGGTGTAGAAGATCCCATGGGAGAAGAATACACTTCACCTGTGGAAGGGGTA
ACAAGACGCTACCCAGACCGTTTGATTATTAATGTAACAAATCAATGTGCTATGTATTGTCGCCACTGCCAACGACGTAG
AAATATCGGGGAAATTGATGTTCACAAATCACGTAAGGTTTTAGAAGGTGCCCTGCAGTATATTAGGGAAAATAAGGAGA
TAAGGGATGTATTAATAACTGGTGGGGATGCTTTATTGTTATCAGACCGACAAATTGAATGGCTGCTGACTGAATTAGAT
AATATTCCTCATGTGGAAATTAAGAGATTGGGAACACGTACTCCGGTTACTATGCCCCAAAGAATTACACCGGAGTTATG
TAAGATTTTAGAGAACCATCCACCGATTTATATCAACACCCAGTTTAATCATCCTTTGGAAGTTACACCAGAAGCAAAAA
AGGCCTGTGATATGTTGGTAAAAGCAGGTGTTGTTCTAGGTAATCAAGCTGTACTACTAAAAAATATAAATAACCAACCG
GATGTTATGAAGAGGTTAAACCAAAGTCTCCTAACCATTCGAGTTCGCCCTTACTATATATTCCATGCTAAAGCCGTAAA
AGGAACCAGACATTTTATCACTGGAGTAGATGACGGCATTGCTATTATGGAACAATTAAGAGGCTATACCTCAGGACTTG
CTGTTCCTACGTATATCATTAATGCCCCCAATGGTTATGGTAAAACTCCTGTACTTCCCCAGTATATTATTGAGAATAAA
AATGATCAAGTTACCCTTAGAACCTGGGAAAAGAGGATTATTCCCTATAATATTAGCGGAAAACATTAG

Upstream 100 bases:

>100_bases
ACTTTTGGGGTGAGTCCGGTTTTTAACGCCGGTAGGGTTTTAACCTTTCGGCCCGAACCCGTCAGCTAACTTCGTAGGCT
TTAAAGAAAGGGGAGTTTTT

Downstream 100 bases:

>100_bases
TGATACGAAAAATCCTGTCATAAAAATGGCAGGATTTTTTATATAGTATTGACAGGAACATTTGTTTGGTAATAAAATAA
ACAAAACAAATGTTCGGAGG

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSVHLKQEEFRLRQEKRKIALKRAKELKARITDYLENKDQIKNGFEVQEQYNRAKQTLLNFFNADNEQWENWHWQMANRI
KDVKVISQLIDLSPAEKEAIEKVGRQYRWAVSPYYMALAMVSGSGGPVWLQAIPCIEEVKDRYGVEDPMGEEYTSPVEGV
TRRYPDRLIINVTNQCAMYCRHCQRRRNIGEIDVHKSRKVLEGALQYIRENKEIRDVLITGGDALLLSDRQIEWLLTELD
NIPHVEIKRLGTRTPVTMPQRITPELCKILENHPPIYINTQFNHPLEVTPEAKKACDMLVKAGVVLGNQAVLLKNINNQP
DVMKRLNQSLLTIRVRPYYIFHAKAVKGTRHFITGVDDGIAIMEQLRGYTSGLAVPTYIINAPNGYGKTPVLPQYIIENK
NDQVTLRTWEKRIIPYNISGKH

Sequences:

>Translated_422_residues
MSVHLKQEEFRLRQEKRKIALKRAKELKARITDYLENKDQIKNGFEVQEQYNRAKQTLLNFFNADNEQWENWHWQMANRI
KDVKVISQLIDLSPAEKEAIEKVGRQYRWAVSPYYMALAMVSGSGGPVWLQAIPCIEEVKDRYGVEDPMGEEYTSPVEGV
TRRYPDRLIINVTNQCAMYCRHCQRRRNIGEIDVHKSRKVLEGALQYIRENKEIRDVLITGGDALLLSDRQIEWLLTELD
NIPHVEIKRLGTRTPVTMPQRITPELCKILENHPPIYINTQFNHPLEVTPEAKKACDMLVKAGVVLGNQAVLLKNINNQP
DVMKRLNQSLLTIRVRPYYIFHAKAVKGTRHFITGVDDGIAIMEQLRGYTSGLAVPTYIINAPNGYGKTPVLPQYIIENK
NDQVTLRTWEKRIIPYNISGKH
>Mature_421_residues
SVHLKQEEFRLRQEKRKIALKRAKELKARITDYLENKDQIKNGFEVQEQYNRAKQTLLNFFNADNEQWENWHWQMANRIK
DVKVISQLIDLSPAEKEAIEKVGRQYRWAVSPYYMALAMVSGSGGPVWLQAIPCIEEVKDRYGVEDPMGEEYTSPVEGVT
RRYPDRLIINVTNQCAMYCRHCQRRRNIGEIDVHKSRKVLEGALQYIRENKEIRDVLITGGDALLLSDRQIEWLLTELDN
IPHVEIKRLGTRTPVTMPQRITPELCKILENHPPIYINTQFNHPLEVTPEAKKACDMLVKAGVVLGNQAVLLKNINNQPD
VMKRLNQSLLTIRVRPYYIFHAKAVKGTRHFITGVDDGIAIMEQLRGYTSGLAVPTYIINAPNGYGKTPVLPQYIIENKN
DQVTLRTWEKRIIPYNISGKH

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=325, Percent_Identity=28.6153846153846, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 48840; Mature: 48709

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHLKQEEFRLRQEKRKIALKRAKELKARITDYLENKDQIKNGFEVQEQYNRAKQTLLN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
FFNADNEQWENWHWQMANRIKDVKVISQLIDLSPAEKEAIEKVGRQYRWAVSPYYMALAM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCHHHHHHHH
VSGSGGPVWLQAIPCIEEVKDRYGVEDPMGEEYTSPVEGVTRRYPDRLIINVTNQCAMYC
CCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHHHH
RHCQRRRNIGEIDVHKSRKVLEGALQYIRENKEIRDVLITGGDALLLSDRQIEWLLTELD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHC
NIPHVEIKRLGTRTPVTMPQRITPELCKILENHPPIYINTQFNHPLEVTPEAKKACDMLV
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
KAGVVLGNQAVLLKNINNQPDVMKRLNQSLLTIRVRPYYIFHAKAVKGTRHFITGVDDGI
HHHHHCCCCEEEEECCCCCHHHHHHHCHHEEEEEEEEEEEEEEHHHCCCHHHCCCCCHHH
AIMEQLRGYTSGLAVPTYIINAPNGYGKTPVLPQYIIENKNDQVTLRTWEKRIIPYNISG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEECCCEEEEECCCC
KH
CC
>Mature Secondary Structure 
SVHLKQEEFRLRQEKRKIALKRAKELKARITDYLENKDQIKNGFEVQEQYNRAKQTLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
FFNADNEQWENWHWQMANRIKDVKVISQLIDLSPAEKEAIEKVGRQYRWAVSPYYMALAM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCHHHHHHHH
VSGSGGPVWLQAIPCIEEVKDRYGVEDPMGEEYTSPVEGVTRRYPDRLIINVTNQCAMYC
CCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHHHH
RHCQRRRNIGEIDVHKSRKVLEGALQYIRENKEIRDVLITGGDALLLSDRQIEWLLTELD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHC
NIPHVEIKRLGTRTPVTMPQRITPELCKILENHPPIYINTQFNHPLEVTPEAKKACDMLV
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
KAGVVLGNQAVLLKNINNQPDVMKRLNQSLLTIRVRPYYIFHAKAVKGTRHFITGVDDGI
HHHHHCCCCEEEEECCCCCHHHHHHHCHHEEEEEEEEEEEEEEHHHCCCHHHCCCCCHHH
AIMEQLRGYTSGLAVPTYIINAPNGYGKTPVLPQYIIENKNDQVTLRTWEKRIIPYNISG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEECCCEEEEECCCC
KH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]