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The map label for this gene is recG [H]

Identifier: 134299934

GI number: 134299934

Start: 2283609

End: 2285666

Strand: Reverse

Name: recG [H]

Synonym: Dred_2088

Alternate gene names: 134299934

Gene position: 2285666-2283609 (Counterclockwise)

Preceding gene: 134299936

Following gene: 134299933

Centisome position: 63.35

GC content: 47.91

Gene sequence:

>2058_bases
ATGCTGGATATATATAGTCCAATACAATACATGAAAGGCGTAGGTCCCCAGAGGGCTAAGCAACTGGAACGCCTGGGTAT
TTTTACCACTTGGGATCTGCTTTATCATTTTCCTAGGGAATATCAGGACAGAAGTGACATACGACCAGCTCACTCCTTTA
GCCAAGGGGATCTTGCCACAGTCAAGGGTACTGTCATTGCAGCCCAGGAAAGCAAACCCCGCAGGGGCCTATCCATAACG
AAATTAGCTTTACAGGAAGGGGCCGGCACCTTTTATGCTGTTTGGTTTAACCAGACCTATATAAAAAAACAGTATCCGCC
TGGTAAGGAACTACTTATAACAGGAAAGGTTGATCGGAAGTTTGGTGTTCCTCAAATTCAGGTTACTGACCATGAGGTCC
TAGAGGGAGATGAAGGGATGCATAGCGGTAGAATTGTCCCCATCTATCCACTGACAGAAAGTCTTAACCAGCGTTTTTTG
AGGTCCCTAATCAAAACAACCCTTGAACAAGTGGGGTCCTTAGCCAGGGAATTTTTGCCGGACTCTATGCTAGACCGTTA
TAATTTGCCTTGCCTACCAGAGGCCCTTCGGGAAATTCATTTTCCTGAAAATCAGGCATCCTGTCAACGGGCCCGACGAC
GGTTTATTATGGAGGAGCTTTTCTTATTTGAGTTAGGGGTAAACCTCCAAAAGGGGCGTATTCTTAAAAAGGTTAAAAAA
CACGAATACATTGAAGAAGCCTTGTCAAATCGTCTTCTCATGAGCCTGCCCTTCCGATTAACTGAAGCCCAGAAACGTGT
GTGGCGGGAGATTGAGGAAGACTTGAAAAGCTCTTTTCCCATGAACCGCCTGTTACAAGGGGATGTGGGGGCAGGTAAAA
CAGTCATAGCAGCTTTGACCCTCTGCAAGGCGGCTGGTTCTGGCCTACAAGGAGCCCTCATGGCTCCTACAGAACTCTTG
GCAGAACAACACGCCAAGGGCATAAAGGATTTACTAGAACCCATGGGGATTAAGGTGGCGCTGTTGACGGGCAGTGGCAA
AAAAGGGAGAAAAAAGACACTGGACGCCCTGGCCTCCGGGGATATACAGGTGGCGATCGGAACCCATGCTTTGATATCCG
AGGATGTCCAGTATAAAAACCTTGGCCTAGTTGTGGTGGATGAACAGCACCGCTTTGGGGTTCGCCAGCGTGCTGCCCTG
CAGGATAAAGGGGTTGCGCCGGATGTACTGGTGATGACTGCAACACCCATTCCCCGTACCCTGGCCCTAACATTATATGG
AGATTTGGATGTATCCATCATTGACCAGTTGCCACCTGGTAGACAAGGGATAAAAACCCATCATGTCGGTTTAGCGCAGG
CTGGCAAGGCTGTGGGATTGATTAAACAACAAATAACTGAAGGCAGACAAGCCTACGTTGTCTGTCCGCTGGTGGAAGAG
TCGGAAAAAATTGATACCCAGGCAGCAGTGGAATTGCATGGCAGACTTCAGAAGGCCCTTGTTGATTGCTCCATAGGCTT
GCTTCATGGACGGATGAAAACACAGGAAAAAGAGTTAGTCATGAATGAATTTCGCAAGGGGACCATTGATTTGTTAGTGT
CCACCACCGTCATTGAGGTAGGGGTGGATGTTCCCAATGCCACTGCCATGGTAATTTGGGATGCCCAACGTTTTGGGTTG
GCTCAACTGCACCAGCTAAGGGGTAGGGTAGGACGGGGCAGTCATCAATCCTACTGTATTTTGGTCGGAGATCCCACCAC
CCGGGAAGCTAAAGAAAGAATGGCCGCCATGTGCCGGACCCAGGATGGTTTTGTTTTAGCAGAAGAAGATTTGAAGCTAC
GGGGTCCCGGTGAATTTTTTGGCACCCGACAATCGGGTTTGCCAGAGTTTAAAATTGCCGACCTGATTAGAAATGGTAAA
GAAATCGAACAGGCAAAAAAGGAAGCGGAAGCCCTGCTAAGTTTGAATCCAGATTTAAGGTCACCCATGCATAAACAACT
ATTTGAACAATTTGCCAGTCGCTTCCCGGATTTTGTTAAGTACAGTGATGTAAGCTAA

Upstream 100 bases:

>100_bases
CCACAAATTAAGTTAAAATCAAATGAAAAATAATAAATCTTACTACCATGGTAATTGCTCCCATGCTATAATAGAACATA
TGTTTTAGAATGGTGATATT

Downstream 100 bases:

>100_bases
GGCGTGGTAGCAATACCACGCCTTTGTTAAGATTTACTTGGTATGATGATTAAGTCCTACCAAATAATAAGTATAGAGGT
GATAAAAATGCCAATCAACA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MLDIYSPIQYMKGVGPQRAKQLERLGIFTTWDLLYHFPREYQDRSDIRPAHSFSQGDLATVKGTVIAAQESKPRRGLSIT
KLALQEGAGTFYAVWFNQTYIKKQYPPGKELLITGKVDRKFGVPQIQVTDHEVLEGDEGMHSGRIVPIYPLTESLNQRFL
RSLIKTTLEQVGSLAREFLPDSMLDRYNLPCLPEALREIHFPENQASCQRARRRFIMEELFLFELGVNLQKGRILKKVKK
HEYIEEALSNRLLMSLPFRLTEAQKRVWREIEEDLKSSFPMNRLLQGDVGAGKTVIAALTLCKAAGSGLQGALMAPTELL
AEQHAKGIKDLLEPMGIKVALLTGSGKKGRKKTLDALASGDIQVAIGTHALISEDVQYKNLGLVVVDEQHRFGVRQRAAL
QDKGVAPDVLVMTATPIPRTLALTLYGDLDVSIIDQLPPGRQGIKTHHVGLAQAGKAVGLIKQQITEGRQAYVVCPLVEE
SEKIDTQAAVELHGRLQKALVDCSIGLLHGRMKTQEKELVMNEFRKGTIDLLVSTTVIEVGVDVPNATAMVIWDAQRFGL
AQLHQLRGRVGRGSHQSYCILVGDPTTREAKERMAAMCRTQDGFVLAEEDLKLRGPGEFFGTRQSGLPEFKIADLIRNGK
EIEQAKKEAEALLSLNPDLRSPMHKQLFEQFASRFPDFVKYSDVS

Sequences:

>Translated_685_residues
MLDIYSPIQYMKGVGPQRAKQLERLGIFTTWDLLYHFPREYQDRSDIRPAHSFSQGDLATVKGTVIAAQESKPRRGLSIT
KLALQEGAGTFYAVWFNQTYIKKQYPPGKELLITGKVDRKFGVPQIQVTDHEVLEGDEGMHSGRIVPIYPLTESLNQRFL
RSLIKTTLEQVGSLAREFLPDSMLDRYNLPCLPEALREIHFPENQASCQRARRRFIMEELFLFELGVNLQKGRILKKVKK
HEYIEEALSNRLLMSLPFRLTEAQKRVWREIEEDLKSSFPMNRLLQGDVGAGKTVIAALTLCKAAGSGLQGALMAPTELL
AEQHAKGIKDLLEPMGIKVALLTGSGKKGRKKTLDALASGDIQVAIGTHALISEDVQYKNLGLVVVDEQHRFGVRQRAAL
QDKGVAPDVLVMTATPIPRTLALTLYGDLDVSIIDQLPPGRQGIKTHHVGLAQAGKAVGLIKQQITEGRQAYVVCPLVEE
SEKIDTQAAVELHGRLQKALVDCSIGLLHGRMKTQEKELVMNEFRKGTIDLLVSTTVIEVGVDVPNATAMVIWDAQRFGL
AQLHQLRGRVGRGSHQSYCILVGDPTTREAKERMAAMCRTQDGFVLAEEDLKLRGPGEFFGTRQSGLPEFKIADLIRNGK
EIEQAKKEAEALLSLNPDLRSPMHKQLFEQFASRFPDFVKYSDVS
>Mature_685_residues
MLDIYSPIQYMKGVGPQRAKQLERLGIFTTWDLLYHFPREYQDRSDIRPAHSFSQGDLATVKGTVIAAQESKPRRGLSIT
KLALQEGAGTFYAVWFNQTYIKKQYPPGKELLITGKVDRKFGVPQIQVTDHEVLEGDEGMHSGRIVPIYPLTESLNQRFL
RSLIKTTLEQVGSLAREFLPDSMLDRYNLPCLPEALREIHFPENQASCQRARRRFIMEELFLFELGVNLQKGRILKKVKK
HEYIEEALSNRLLMSLPFRLTEAQKRVWREIEEDLKSSFPMNRLLQGDVGAGKTVIAALTLCKAAGSGLQGALMAPTELL
AEQHAKGIKDLLEPMGIKVALLTGSGKKGRKKTLDALASGDIQVAIGTHALISEDVQYKNLGLVVVDEQHRFGVRQRAAL
QDKGVAPDVLVMTATPIPRTLALTLYGDLDVSIIDQLPPGRQGIKTHHVGLAQAGKAVGLIKQQITEGRQAYVVCPLVEE
SEKIDTQAAVELHGRLQKALVDCSIGLLHGRMKTQEKELVMNEFRKGTIDLLVSTTVIEVGVDVPNATAMVIWDAQRFGL
AQLHQLRGRVGRGSHQSYCILVGDPTTREAKERMAAMCRTQDGFVLAEEDLKLRGPGEFFGTRQSGLPEFKIADLIRNGK
EIEQAKKEAEALLSLNPDLRSPMHKQLFEQFASRFPDFVKYSDVS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=696, Percent_Identity=41.3793103448276, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1787357, Length=379, Percent_Identity=38.5224274406332, Blast_Score=245, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76429; Mature: 76429

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIYSPIQYMKGVGPQRAKQLERLGIFTTWDLLYHFPREYQDRSDIRPAHSFSQGDLAT
CCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEE
VKGTVIAAQESKPRRGLSITKLALQEGAGTFYAVWFNQTYIKKQYPPGKELLITGKVDRK
ECEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCEEEEEECCCCC
FGVPQIQVTDHEVLEGDEGMHSGRIVPIYPLTESLNQRFLRSLIKTTLEQVGSLAREFLP
CCCCEEEECCHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSMLDRYNLPCLPEALREIHFPENQASCQRARRRFIMEELFLFELGVNLQKGRILKKVKK
HHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HEYIEEALSNRLLMSLPFRLTEAQKRVWREIEEDLKSSFPMNRLLQGDVGAGKTVIAALT
HHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHH
LCKAAGSGLQGALMAPTELLAEQHAKGIKDLLEPMGIKVALLTGSGKKGRKKTLDALASG
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCC
DIQVAIGTHALISEDVQYKNLGLVVVDEQHRFGVRQRAALQDKGVAPDVLVMTATPIPRT
CEEEEECCHHHHHCCCCCCCCCEEEECCHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCE
LALTLYGDLDVSIIDQLPPGRQGIKTHHVGLAQAGKAVGLIKQQITEGRQAYVVCPLVEE
EEEEEECCCCHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCEEEEEEECCC
SEKIDTQAAVELHGRLQKALVDCSIGLLHGRMKTQEKELVMNEFRKGTIDLLVSTTVIEV
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEEEEE
GVDVPNATAMVIWDAQRFGLAQLHQLRGRVGRGSHQSYCILVGDPTTREAKERMAAMCRT
CCCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
QDGFVLAEEDLKLRGPGEFFGTRQSGLPEFKIADLIRNGKEIEQAKKEAEALLSLNPDLR
CCCEEEECCCCEECCCCHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHC
SPMHKQLFEQFASRFPDFVKYSDVS
CHHHHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure
MLDIYSPIQYMKGVGPQRAKQLERLGIFTTWDLLYHFPREYQDRSDIRPAHSFSQGDLAT
CCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEE
VKGTVIAAQESKPRRGLSITKLALQEGAGTFYAVWFNQTYIKKQYPPGKELLITGKVDRK
ECEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCEEEEEECCCCC
FGVPQIQVTDHEVLEGDEGMHSGRIVPIYPLTESLNQRFLRSLIKTTLEQVGSLAREFLP
CCCCEEEECCHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSMLDRYNLPCLPEALREIHFPENQASCQRARRRFIMEELFLFELGVNLQKGRILKKVKK
HHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HEYIEEALSNRLLMSLPFRLTEAQKRVWREIEEDLKSSFPMNRLLQGDVGAGKTVIAALT
HHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHH
LCKAAGSGLQGALMAPTELLAEQHAKGIKDLLEPMGIKVALLTGSGKKGRKKTLDALASG
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCC
DIQVAIGTHALISEDVQYKNLGLVVVDEQHRFGVRQRAALQDKGVAPDVLVMTATPIPRT
CEEEEECCHHHHHCCCCCCCCCEEEECCHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCE
LALTLYGDLDVSIIDQLPPGRQGIKTHHVGLAQAGKAVGLIKQQITEGRQAYVVCPLVEE
EEEEEECCCCHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCEEEEEEECCC
SEKIDTQAAVELHGRLQKALVDCSIGLLHGRMKTQEKELVMNEFRKGTIDLLVSTTVIEV
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEEEEE
GVDVPNATAMVIWDAQRFGLAQLHQLRGRVGRGSHQSYCILVGDPTTREAKERMAAMCRT
CCCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
QDGFVLAEEDLKLRGPGEFFGTRQSGLPEFKIADLIRNGKEIEQAKKEAEALLSLNPDLR
CCCEEEECCCCEECCCCHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHC
SPMHKQLFEQFASRFPDFVKYSDVS
CHHHHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]