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The map label for this gene is coaD

Identifier: 134299930

GI number: 134299930

Start: 2281106

End: 2281591

Strand: Reverse

Name: coaD

Synonym: Dred_2084

Alternate gene names: 134299930

Gene position: 2281591-2281106 (Counterclockwise)

Preceding gene: 134299931

Following gene: 134299929

Centisome position: 63.24

GC content: 40.12

Gene sequence:

>486_bases
ATGCGTATAGGAGTTTACCCCGGTAGTTTTGACCCAGTTACCAATGGACACATGGATATCGTAGAACGATCTGTGGGACT
TTTTGATCGTCTTATTGTTGCAGTGGCGAAAAATGCACAAAAAAAACCGCTTTTCTCGGTGGAGGAGCGGGTTGAAATAT
TGAAAAATGTTCTGAAAAAATATCCGAATATTGTTGTGGACACCTTTGACGGCCTTACCGTAACCTATGCATTGCAACAG
GGGGCCATTGCCATTGTACGCGGGCTTAGGGCCTTTTCAGATTTTGAAAATGAATTTATTTTTGCCTTAACCAATAAAAA
ATTGGCACCAGATCTTGAAACTGTTTATCTGATGACCAGGGCAGAATATTCTTTCATTAGTTCCACAACGGTTAAGGAAG
TGGCCTCATTTAAAGGCTCCTTAAGTGGTATGGTTCCAGAGATTGTAGCTCAAAAAATACAAGACAAATATGGCTATGGT
AAATAA

Upstream 100 bases:

>100_bases
GCCGCCGGATCTAGTGGGAAATCTAACCGCAACTCGAAGAGAACGGTATGGCGATACAGCGTTGACATTCTATAGGCTTC
CCAGTTGAGGAGGAATATGG

Downstream 100 bases:

>100_bases
CCAAGGAGGGATATAACTGTGGAGCTCTTTAATATCCTGAATGAGCTGGAGGAACTCATTGAGGAGAGCCCCAAGGTGCC
AATGACCAAACGAGTCATGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRIGVYPGSFDPVTNGHMDIVERSVGLFDRLIVAVAKNAQKKPLFSVEERVEILKNVLKKYPNIVVDTFDGLTVTYALQQ
GAIAIVRGLRAFSDFENEFIFALTNKKLAPDLETVYLMTRAEYSFISSTTVKEVASFKGSLSGMVPEIVAQKIQDKYGYG
K

Sequences:

>Translated_161_residues
MRIGVYPGSFDPVTNGHMDIVERSVGLFDRLIVAVAKNAQKKPLFSVEERVEILKNVLKKYPNIVVDTFDGLTVTYALQQ
GAIAIVRGLRAFSDFENEFIFALTNKKLAPDLETVYLMTRAEYSFISSTTVKEVASFKGSLSGMVPEIVAQKIQDKYGYG
K
>Mature_161_residues
MRIGVYPGSFDPVTNGHMDIVERSVGLFDRLIVAVAKNAQKKPLFSVEERVEILKNVLKKYPNIVVDTFDGLTVTYALQQ
GAIAIVRGLRAFSDFENEFIFALTNKKLAPDLETVYLMTRAEYSFISSTTVKEVASFKGSLSGMVPEIVAQKIQDKYGYG
K

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=44.5161290322581, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_DESRM (A4J698)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113426.1
- ProteinModelPortal:   A4J698
- SMR:   A4J698
- STRING:   A4J698
- GeneID:   4957660
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2084
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   A4J698
- ProtClustDB:   PRK00168
- BioCyc:   DRED349161:DRED_2084-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17935; Mature: 17935

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVYPGSFDPVTNGHMDIVERSVGLFDRLIVAVAKNAQKKPLFSVEERVEILKNVLKK
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
YPNIVVDTFDGLTVTYALQQGAIAIVRGLRAFSDFENEFIFALTNKKLAPDLETVYLMTR
CCCEEEECCCCCEEEEHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
AEYSFISSTTVKEVASFKGSLSGMVPEIVAQKIQDKYGYGK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIGVYPGSFDPVTNGHMDIVERSVGLFDRLIVAVAKNAQKKPLFSVEERVEILKNVLKK
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
YPNIVVDTFDGLTVTYALQQGAIAIVRGLRAFSDFENEFIFALTNKKLAPDLETVYLMTR
CCCEEEECCCCCEEEEHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
AEYSFISSTTVKEVASFKGSLSGMVPEIVAQKIQDKYGYGK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA