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The map label for this gene is nrnA [H]

Identifier: 134299802

GI number: 134299802

Start: 2145575

End: 2146546

Strand: Reverse

Name: nrnA [H]

Synonym: Dred_1955

Alternate gene names: 134299802

Gene position: 2146546-2145575 (Counterclockwise)

Preceding gene: 134299803

Following gene: 134299801

Centisome position: 59.49

GC content: 43.42

Gene sequence:

>972_bases
ATGAATAACTTGAGGACAGTGGCAGATGTGCTGGAGAAGTCAAGTAGACCCTTGCTGTGTGGTCATATTATGCCAGATGG
TGATAGCCTTGGCTCTGTCCTAGCGTTAGGTATGGGGTTACAATCTGTAGGTAAAGAGGTAACTATAGTTAGTTCAGACC
CACTGCCGGACTTATATCGATTTCTTCCCGGGATCGATGAGATTGTTGTGGGCAGTGTACCTGATCGCAAATATGATTTA
CTTGTGGTGGTAGACTGTTCGGTGCCGGAGCGCCTTGGTTCTACCATCACTCCCACAGTGGACTCAGGTTTGCCAGTGGT
AGTTATCGATCACCATGTTAATGATCAGCCCTTTGGACACCATAACTACGTAAGATCAAGTGCAGCAGCCACTGGGGAAA
TAATTATGGAACTGCTGGAGTTATTAGGTGTTTCCATCAATTTGGATATAGCCATCAATCTTTATACAGCCATTGTTACA
GATACTGGTTCATTTCGTTTTGAAAACACCACTCCAGAAACCCACAGTAAGGCAGCAGAACTGGTGAAGTTTGGAGTTCC
AGTTTCCCGTTTATCCAATCTGATTTTTGGGGAACAGCCTCTGAAATCGATCAGATTATTGGAAGCTGCCTTAAATAGCC
TTGAAGTCAGTGATTGTGGTCGCATTGCTTGGATAAGTATTGACCGTGATAAAATTGATGCGTTGGGTGCTGAGGATCAG
CATATAGAAGGTCTAATAAGTTACCCCCGTAAAATTAAGGGTGTTGAGTTAGCTATTTCCTTTAGGGAATTGGATAAGCA
AAAGGTAAAGGTTAGTTTTCGGTCTAAATATACGGTGGATGTTAACTTTTTAGCTAAAAAATTTGGTGGCGGAGGACATG
TTCGAGCCTCAGGGTGTACCATTCAAGGTACACTTCAGGAAGTTAAGGAAGTCGTTCTCAAGGAAGCCCAAGAAATATTC
CGGGGGTGTTAA

Upstream 100 bases:

>100_bases
GCCCCAGAATTAATATTTAAATTAGATACTTCACTGGATCACGGAACTCGAATAGCTGAAATTCTTCATGAGATAAACTC
TCAGGAGGCAAAGCCAACTC

Downstream 100 bases:

>100_bases
GGTGGATGGGGTCATCAATATCTTAAAGCCTCCGGGAATGACATCCCACGATGTTGTATTCTTTGTAAGACGGGTTACTG
GGGTGAAGAAATGTGGGCAT

Product: phosphoesterase domain-containing protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNNLRTVADVLEKSSRPLLCGHIMPDGDSLGSVLALGMGLQSVGKEVTIVSSDPLPDLYRFLPGIDEIVVGSVPDRKYDL
LVVVDCSVPERLGSTITPTVDSGLPVVVIDHHVNDQPFGHHNYVRSSAAATGEIIMELLELLGVSINLDIAINLYTAIVT
DTGSFRFENTTPETHSKAAELVKFGVPVSRLSNLIFGEQPLKSIRLLEAALNSLEVSDCGRIAWISIDRDKIDALGAEDQ
HIEGLISYPRKIKGVELAISFRELDKQKVKVSFRSKYTVDVNFLAKKFGGGGHVRASGCTIQGTLQEVKEVVLKEAQEIF
RGC

Sequences:

>Translated_323_residues
MNNLRTVADVLEKSSRPLLCGHIMPDGDSLGSVLALGMGLQSVGKEVTIVSSDPLPDLYRFLPGIDEIVVGSVPDRKYDL
LVVVDCSVPERLGSTITPTVDSGLPVVVIDHHVNDQPFGHHNYVRSSAAATGEIIMELLELLGVSINLDIAINLYTAIVT
DTGSFRFENTTPETHSKAAELVKFGVPVSRLSNLIFGEQPLKSIRLLEAALNSLEVSDCGRIAWISIDRDKIDALGAEDQ
HIEGLISYPRKIKGVELAISFRELDKQKVKVSFRSKYTVDVNFLAKKFGGGGHVRASGCTIQGTLQEVKEVVLKEAQEIF
RGC
>Mature_323_residues
MNNLRTVADVLEKSSRPLLCGHIMPDGDSLGSVLALGMGLQSVGKEVTIVSSDPLPDLYRFLPGIDEIVVGSVPDRKYDL
LVVVDCSVPERLGSTITPTVDSGLPVVVIDHHVNDQPFGHHNYVRSSAAATGEIIMELLELLGVSINLDIAINLYTAIVT
DTGSFRFENTTPETHSKAAELVKFGVPVSRLSNLIFGEQPLKSIRLLEAALNSLEVSDCGRIAWISIDRDKIDALGAEDQ
HIEGLISYPRKIKGVELAISFRELDKQKVKVSFRSKYTVDVNFLAKKFGGGGHVRASGCTIQGTLQEVKEVVLKEAQEIF
RGC

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35120; Mature: 35120

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLRTVADVLEKSSRPLLCGHIMPDGDSLGSVLALGMGLQSVGKEVTIVSSDPLPDLYR
CCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCEEEEEECCCCHHHHH
FLPGIDEIVVGSVPDRKYDLLVVVDCSVPERLGSTITPTVDSGLPVVVIDHHVNDQPFGH
HCCCCCCEEECCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCC
HNYVRSSAAATGEIIMELLELLGVSINLDIAINLYTAIVTDTGSFRFENTTPETHSKAAE
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEECCCCEEECCCCCHHHHHHHH
LVKFGVPVSRLSNLIFGEQPLKSIRLLEAALNSLEVSDCGRIAWISIDRDKIDALGAEDQ
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHCCCCCH
HIEGLISYPRKIKGVELAISFRELDKQKVKVSFRSKYTVDVNFLAKKFGGGGHVRASGCT
HHHHHHHCCHHCCCEEEEEEHHHHCCHHEEEEECCEEEEEHHHHHHHCCCCCEEEECCCE
IQGTLQEVKEVVLKEAQEIFRGC
EEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNLRTVADVLEKSSRPLLCGHIMPDGDSLGSVLALGMGLQSVGKEVTIVSSDPLPDLYR
CCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHCCEEEEEECCCCHHHHH
FLPGIDEIVVGSVPDRKYDLLVVVDCSVPERLGSTITPTVDSGLPVVVIDHHVNDQPFGH
HCCCCCCEEECCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCC
HNYVRSSAAATGEIIMELLELLGVSINLDIAINLYTAIVTDTGSFRFENTTPETHSKAAE
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEECCCCEEECCCCCHHHHHHHH
LVKFGVPVSRLSNLIFGEQPLKSIRLLEAALNSLEVSDCGRIAWISIDRDKIDALGAEDQ
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHCCCCCH
HIEGLISYPRKIKGVELAISFRELDKQKVKVSFRSKYTVDVNFLAKKFGGGGHVRASGCT
HHHHHHHCCHHCCCEEEEEEHHHHCCHHEEEEECCEEEEEHHHHHHHCCCCCEEEECCCE
IQGTLQEVKEVVLKEAQEIFRGC
EEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]