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The map label for this gene is pgsA [H]

Identifier: 134299775

GI number: 134299775

Start: 2115325

End: 2115870

Strand: Reverse

Name: pgsA [H]

Synonym: Dred_1925

Alternate gene names: 134299775

Gene position: 2115870-2115325 (Counterclockwise)

Preceding gene: 134299776

Following gene: 134299774

Centisome position: 58.64

GC content: 40.84

Gene sequence:

>546_bases
ATGAATTTACCGAACCGGTTGACTCTGGCAAGAATGTTTTTAATTCCTGTTTTTTTGGCAGTGGTTACTTTAAGAATTAA
ATATGGCGATATAATAGCTGCTGGGGTTTTTATTTTAGCTGCTAGTACCGATGGTCTTGACGGTTACATTGCGAGAAAAA
ATAAACAAGTAACCACCCTTGGTAAATTTATGGATCCACTGGCGGATAAACTTTTGGTATCGGCGGCTCTTATTGTCCTG
GTGGAGTTGGACAAATTGTCAGCTTGGGTTGCTATAATCATTATAGGACGTGAATTTATGGTGACCGGCCTTAGGGCAAT
AGCAGCAACAGAGGGTGTGGTCATCTCTGCCAGTAAACTGGGGAAGTGGAAAACGGTAACCCAAATTGTTGCTATTGTGG
CTATGTTTTTGCATAATATAACCTTTCAATTTTTAGGGTTTGATTTGGGGAAAATTGCAATGGCTGTGGCGGTTTTCTTT
ACCCTTTGGTCTGGAATCGACTATATGGCCAAAGGATGGCACCTGCTAAAAAAAGAAGAGTACTAG

Upstream 100 bases:

>100_bases
CCGTAGAATTTACCAGTTCAAGACCATTACGGATTGGTGATTTTGTTAAAGTAAAGATTAATAGGGCATTAGAGTATGAT
TTGATGGGAGAGTTGGCCCA

Downstream 100 bases:

>100_bases
AACAGGAGAGCATTTTGCTTTCCTGTTTTTTTAATTTCCAACGGTTTCATAAAGAATCGTATATACTAACGTGCTATAAT
GATATAGCATTAAATCAGTA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MNLPNRLTLARMFLIPVFLAVVTLRIKYGDIIAAGVFILAASTDGLDGYIARKNKQVTTLGKFMDPLADKLLVSAALIVL
VELDKLSAWVAIIIIGREFMVTGLRAIAATEGVVISASKLGKWKTVTQIVAIVAMFLHNITFQFLGFDLGKIAMAVAVFF
TLWSGIDYMAKGWHLLKKEEY

Sequences:

>Translated_181_residues
MNLPNRLTLARMFLIPVFLAVVTLRIKYGDIIAAGVFILAASTDGLDGYIARKNKQVTTLGKFMDPLADKLLVSAALIVL
VELDKLSAWVAIIIIGREFMVTGLRAIAATEGVVISASKLGKWKTVTQIVAIVAMFLHNITFQFLGFDLGKIAMAVAVFF
TLWSGIDYMAKGWHLLKKEEY
>Mature_181_residues
MNLPNRLTLARMFLIPVFLAVVTLRIKYGDIIAAGVFILAASTDGLDGYIARKNKQVTTLGKFMDPLADKLLVSAALIVL
VELDKLSAWVAIIIIGREFMVTGLRAIAATEGVVISASKLGKWKTVTQIVAIVAMFLHNITFQFLGFDLGKIAMAVAVFF
TLWSGIDYMAKGWHLLKKEEY

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=177, Percent_Identity=37.2881355932203, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19907; Mature: 19907

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNRLTLARMFLIPVFLAVVTLRIKYGDIIAAGVFILAASTDGLDGYIARKNKQVTTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCHHHH
GKFMDPLADKLLVSAALIVLVELDKLSAWVAIIIIGREFMVTGLRAIAATEGVVISASKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHC
GKWKTVTQIVAIVAMFLHNITFQFLGFDLGKIAMAVAVFFTLWSGIDYMAKGWHLLKKEE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCC
Y
C
>Mature Secondary Structure
MNLPNRLTLARMFLIPVFLAVVTLRIKYGDIIAAGVFILAASTDGLDGYIARKNKQVTTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCHHHH
GKFMDPLADKLLVSAALIVLVELDKLSAWVAIIIIGREFMVTGLRAIAATEGVVISASKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHC
GKWKTVTQIVAIVAMFLHNITFQFLGFDLGKIAMAVAVFFTLWSGIDYMAKGWHLLKKEE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHCHHHHCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]