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The map label for this gene is cat2 [H]

Identifier: 134299178

GI number: 134299178

Start: 1406772

End: 1408097

Strand: Reverse

Name: cat2 [H]

Synonym: Dred_1315

Alternate gene names: 134299178

Gene position: 1408097-1406772 (Counterclockwise)

Preceding gene: 134299180

Following gene: 134299143

Centisome position: 39.03

GC content: 42.16

Gene sequence:

>1326_bases
TTGGTATGGTTTAAAGCGGGTCCGTTATTTGAAGACTCTGATAAGTTGCTCAAAATGTATGAAGAAAAACGTATTTCAGC
AAAGGAAGCTGTAGCCGTTATTTCTTCTGGGGATAATATAGTAGTACCGCCCGGTGCTGCCGAGCCAGAATTGTTAATGG
AAAGCCTGGCAAATCGGAAGGGAGAATTAAAGGACGTCAGAATTCACCAAATGCTGCCTCTACGCGAGGCCAGTTACCTA
AAACCTGGCATGGAAAAACATTTTCGCCATGTTTCTTGGTTAACAAGTAGTGTAGTAAAAAGAGGGGTAAAAGAAGGGCG
GGCCGGCGTCATGCCCGGCTATTTATATGAGTATCCACAGTTTATCCGGGACATGGAAGTCGACGTTTTTATGGGTACGG
TTTCTCCTATGGATGAACATGGCTATTTCAGCTTTGGTGTTTCTGTTGATTACACCATAGCCGCAGCTGGTTGCGCTAAG
AAGGTAATCTTATTGGTTAACCCCAATATGCCTAGAACCATGGGTTACAGCTTTATTCATGTATCCCAGGCTGATATGAT
TGTAGAGGACAGTTCCCCTCTTTTAGAAGTTCCCAAACCAACCCTTAGTAAAAATGATTCTAAAATTGGGGACTATGTAT
GTCAGATCGTGGAGGATGGCTCAACAATACAACTTGGACTGGGCTCCTTAGCCAATTCTGTTGCTCAGTGTCTCTCTGTT
AAAAAAGGGTTGGGTATTCATAGTCACTTTATTACAGATTCCATAGTGGACTTAGTAGAATGTGGCGCCATAACGAATCG
GCGTAAAAAATTACACCTAGGTAAAATTATCTGCAGTTCCGCTGTGGGTACCAAACGTTTATATCAATTCATAAATAATA
ATCCTTTATTTGAATTTCATTCCGTTTCTTATACAAATGACCCCATGGTCATTGCAAAAAATAATAATATGGTAGCAATC
AACTCCGTGGAAGAAATAGATCTTTTAGGTCAGTGCGCTTCTGAACCAATAGGCCCTAAATTATATTCCGGAACCGGAGA
GCAGGTTGATTTTGCACGGGGTGCCATGAATGCTGACAATGGGAAAAGCATTGTCGTACTTCATTCCACTCTTAAGGGAA
GAACAAAAATAGTACCCGTCTTAGAGAGTGGTTCCGTAGTAAGTCTCAGCAAAAATGACGTTGATTATGTTGTCACGGAG
TATGGTTTTGCCCGATTAAGAGGAAAAACCTACCGTCAAAGGGCGGAATCACTCATTGCCATTGCCCATCCGGACCATCG
AGATGGTCTAACAGAGGCTGCAAAAAAGTTTGGTCTAACCAGATAA

Upstream 100 bases:

>100_bases
TCCCTTTGTAATTTCTTTAAAATATGACAACATCTTTCTTTCATTAGCTGATTAAAAGTGATATAATTCACTTAAAGTTG
CACTCTGGAGGTGATTGTTT

Downstream 100 bases:

>100_bases
AAAATATATAACAATATACCCTATAACCCGCATTGCCTGGCAATGCGGGTTATTTATTGCCAAATCTGTTTCAGCAGCTG
TGCCCTTCTTTCTTGTTCTC

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MVWFKAGPLFEDSDKLLKMYEEKRISAKEAVAVISSGDNIVVPPGAAEPELLMESLANRKGELKDVRIHQMLPLREASYL
KPGMEKHFRHVSWLTSSVVKRGVKEGRAGVMPGYLYEYPQFIRDMEVDVFMGTVSPMDEHGYFSFGVSVDYTIAAAGCAK
KVILLVNPNMPRTMGYSFIHVSQADMIVEDSSPLLEVPKPTLSKNDSKIGDYVCQIVEDGSTIQLGLGSLANSVAQCLSV
KKGLGIHSHFITDSIVDLVECGAITNRRKKLHLGKIICSSAVGTKRLYQFINNNPLFEFHSVSYTNDPMVIAKNNNMVAI
NSVEEIDLLGQCASEPIGPKLYSGTGEQVDFARGAMNADNGKSIVVLHSTLKGRTKIVPVLESGSVVSLSKNDVDYVVTE
YGFARLRGKTYRQRAESLIAIAHPDHRDGLTEAAKKFGLTR

Sequences:

>Translated_441_residues
MVWFKAGPLFEDSDKLLKMYEEKRISAKEAVAVISSGDNIVVPPGAAEPELLMESLANRKGELKDVRIHQMLPLREASYL
KPGMEKHFRHVSWLTSSVVKRGVKEGRAGVMPGYLYEYPQFIRDMEVDVFMGTVSPMDEHGYFSFGVSVDYTIAAAGCAK
KVILLVNPNMPRTMGYSFIHVSQADMIVEDSSPLLEVPKPTLSKNDSKIGDYVCQIVEDGSTIQLGLGSLANSVAQCLSV
KKGLGIHSHFITDSIVDLVECGAITNRRKKLHLGKIICSSAVGTKRLYQFINNNPLFEFHSVSYTNDPMVIAKNNNMVAI
NSVEEIDLLGQCASEPIGPKLYSGTGEQVDFARGAMNADNGKSIVVLHSTLKGRTKIVPVLESGSVVSLSKNDVDYVVTE
YGFARLRGKTYRQRAESLIAIAHPDHRDGLTEAAKKFGLTR
>Mature_441_residues
MVWFKAGPLFEDSDKLLKMYEEKRISAKEAVAVISSGDNIVVPPGAAEPELLMESLANRKGELKDVRIHQMLPLREASYL
KPGMEKHFRHVSWLTSSVVKRGVKEGRAGVMPGYLYEYPQFIRDMEVDVFMGTVSPMDEHGYFSFGVSVDYTIAAAGCAK
KVILLVNPNMPRTMGYSFIHVSQADMIVEDSSPLLEVPKPTLSKNDSKIGDYVCQIVEDGSTIQLGLGSLANSVAQCLSV
KKGLGIHSHFITDSIVDLVECGAITNRRKKLHLGKIICSSAVGTKRLYQFINNNPLFEFHSVSYTNDPMVIAKNNNMVAI
NSVEEIDLLGQCASEPIGPKLYSGTGEQVDFARGAMNADNGKSIVVLHSTLKGRTKIVPVLESGSVVSLSKNDVDYVVTE
YGFARLRGKTYRQRAESLIAIAHPDHRDGLTEAAKKFGLTR

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=471, Percent_Identity=23.1422505307856, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563853, Length=422, Percent_Identity=39.0995260663507, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17538151, Length=425, Percent_Identity=36.9411764705882, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21358615, Length=418, Percent_Identity=39.2344497607655, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48462; Mature: 48462

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWFKAGPLFEDSDKLLKMYEEKRISAKEAVAVISSGDNIVVPPGAAEPELLMESLANRK
CCEECCCCCCCCHHHHHHHHHHHCCCHHHHEEEEECCCEEEECCCCCCHHHHHHHHHCCC
GELKDVRIHQMLPLREASYLKPGMEKHFRHVSWLTSSVVKRGVKEGRAGVMPGYLYEYPQ
CCCCEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FIRDMEVDVFMGTVSPMDEHGYFSFGVSVDYTIAAAGCAKKVILLVNPNMPRTMGYSFIH
HHHCCCEEEEEECCCCCCCCCEEEECCEEEEEEEECCCCEEEEEEECCCCCHHHCCEEEE
VSQADMIVEDSSPLLEVPKPTLSKNDSKIGDYVCQIVEDGSTIQLGLGSLANSVAQCLSV
EECCCEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
KKGLGIHSHFITDSIVDLVECGAITNRRKKLHLGKIICSSAVGTKRLYQFINNNPLFEFH
HHCCCCHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEE
SVSYTNDPMVIAKNNNMVAINSVEEIDLLGQCASEPIGPKLYSGTGEQVDFARGAMNADN
ECEECCCCEEEEECCCEEEECCHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHCCCCCCC
GKSIVVLHSTLKGRTKIVPVLESGSVVSLSKNDVDYVVTEYGFARLRGKTYRQRAESLIA
CCEEEEEECCCCCCEEEEEEECCCCEEEECCCCCCEEEEHHHHHHHCCHHHHHHHHCEEE
IAHPDHRDGLTEAAKKFGLTR
EECCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVWFKAGPLFEDSDKLLKMYEEKRISAKEAVAVISSGDNIVVPPGAAEPELLMESLANRK
CCEECCCCCCCCHHHHHHHHHHHCCCHHHHEEEEECCCEEEECCCCCCHHHHHHHHHCCC
GELKDVRIHQMLPLREASYLKPGMEKHFRHVSWLTSSVVKRGVKEGRAGVMPGYLYEYPQ
CCCCEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FIRDMEVDVFMGTVSPMDEHGYFSFGVSVDYTIAAAGCAKKVILLVNPNMPRTMGYSFIH
HHHCCCEEEEEECCCCCCCCCEEEECCEEEEEEEECCCCEEEEEEECCCCCHHHCCEEEE
VSQADMIVEDSSPLLEVPKPTLSKNDSKIGDYVCQIVEDGSTIQLGLGSLANSVAQCLSV
EECCCEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
KKGLGIHSHFITDSIVDLVECGAITNRRKKLHLGKIICSSAVGTKRLYQFINNNPLFEFH
HHCCCCHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEE
SVSYTNDPMVIAKNNNMVAINSVEEIDLLGQCASEPIGPKLYSGTGEQVDFARGAMNADN
ECEECCCCEEEEECCCEEEECCHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHCCCCCCC
GKSIVVLHSTLKGRTKIVPVLESGSVVSLSKNDVDYVVTEYGFARLRGKTYRQRAESLIA
CCEEEEEECCCCCCEEEEEEECCCCEEEECCCCCCEEEEHHHHHHHCCHHHHHHHHCEEE
IAHPDHRDGLTEAAKKFGLTR
EECCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]