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The map label for this gene is yhdR [H]

Identifier: 134299011

GI number: 134299011

Start: 1218445

End: 1219632

Strand: Reverse

Name: yhdR [H]

Synonym: Dred_1148

Alternate gene names: 134299011

Gene position: 1219632-1218445 (Counterclockwise)

Preceding gene: 134299031

Following gene: 134298984

Centisome position: 33.8

GC content: 44.53

Gene sequence:

>1188_bases
ATGGTACTGTCTGATAAAGTAGCCTCTTCTTTAGGCAAAGCTTCCTGGATACGTAAAATGTTTGAAGAAGGTGACCGCCT
AAGAAAAATTTACGGTCCTGAAAAGGTATTTGATTTCACCCTTGGTAATCCCTCCGTAGAACCCCCGGAAAAATTTAACG
AACAATTAAAAACATTAGCCCTTAACCCTGAACCAGGCATGCATCGTTATATGAGCAATGCAGGTTATCCCGAAACCCGC
TCCGCCGTGGCTGAGGTCATAGCGGAACAATCAGACTTGCCCTTTACGGCTCAGCACATCGTCATGACCGTAGGGGCCGG
GGGCGGCCTCAATGTGGTTCTCAAAGCGATCTTAAACCCCGGGGATGAGGTTATTGCACTGTCTCCTTATTTTGTGGAAT
ATGGATTCTATGTTGATAATCATGGGGGAGTCTTAAAGGTTGTTCCTAACGATGAAAAGTTCCTGCCTGATTTAGACGCC
ATCGCCTCTGCTATCAATGAAAAGACCAGAGCCATCATCATTAACTCTCCCAATAACCCTACTGGTGTTGTTTACCCAGC
TGAAACACTGGCATCCTTAGGCAAGTTAGTGACAGAAAAATCTCAACAATGGGGGAGGCCAATCTTTGTCCTTTCGGATG
AACCCTATGCCAAGATTGTTTATGACGGTGTAAAAGTCCCCTCTGTTTTCCCGTATATAACCAATGCAATCATGGTTACC
TCCCACAGTAAAGACCTTGCATTGCCGGGCGAACGTATTGGTTATATTGCAGTTAACCCTAGAATTAACGGAGTTAACCA
ATTGGTAGAAGGTCTAATATTCTGCAACCGTACTTTGGGCTTTGTAAATGCTCCTGCTTTAATGCAACGCCTGGTGAAAG
GATTGCAACGGGAATCCGTCAACATAGAGGAATACCAGGAAAAGCGCGATGTTCTATACAATCATCTTACCTCACTGGGC
TTTGAAATACAGAAGCCCCAAGGAGCCTTTTATCTATTTCCTAAATCACCCCTTGCTGATGACCTTGAATTTACCAGAGT
AGCCCTAAATCACAATATTTTGGTAGTTCCAGGTGGTGGTTTTGGTACACCAGGCTATTTCCGCCTGTCTTACTGCATTG
AAATGGATACCATAAAAAGATCTCTACCGGCCTGGACTAGTCTGGCCCAAGAACTAGGTCTGAAATAA

Upstream 100 bases:

>100_bases
ATCAGATTTAAGACTTGACAATTACAATGGAAAAATATATAAAAATATCTTTTCTAATGGTAAAATAATGGTAAATCGTT
CATATGAAAGGAGTTTGCAA

Downstream 100 bases:

>100_bases
ACAAAGGAACCGGAGCGCTGGTTACGCTCCGGTTCCTTTGTTTATTTCATCTCTCACCAGTAATAAATCTTTAAGACCTC
GCATTAAATTTTTTAATTCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVLSDKVASSLGKASWIRKMFEEGDRLRKIYGPEKVFDFTLGNPSVEPPEKFNEQLKTLALNPEPGMHRYMSNAGYPETR
SAVAEVIAEQSDLPFTAQHIVMTVGAGGGLNVVLKAILNPGDEVIALSPYFVEYGFYVDNHGGVLKVVPNDEKFLPDLDA
IASAINEKTRAIIINSPNNPTGVVYPAETLASLGKLVTEKSQQWGRPIFVLSDEPYAKIVYDGVKVPSVFPYITNAIMVT
SHSKDLALPGERIGYIAVNPRINGVNQLVEGLIFCNRTLGFVNAPALMQRLVKGLQRESVNIEEYQEKRDVLYNHLTSLG
FEIQKPQGAFYLFPKSPLADDLEFTRVALNHNILVVPGGGFGTPGYFRLSYCIEMDTIKRSLPAWTSLAQELGLK

Sequences:

>Translated_395_residues
MVLSDKVASSLGKASWIRKMFEEGDRLRKIYGPEKVFDFTLGNPSVEPPEKFNEQLKTLALNPEPGMHRYMSNAGYPETR
SAVAEVIAEQSDLPFTAQHIVMTVGAGGGLNVVLKAILNPGDEVIALSPYFVEYGFYVDNHGGVLKVVPNDEKFLPDLDA
IASAINEKTRAIIINSPNNPTGVVYPAETLASLGKLVTEKSQQWGRPIFVLSDEPYAKIVYDGVKVPSVFPYITNAIMVT
SHSKDLALPGERIGYIAVNPRINGVNQLVEGLIFCNRTLGFVNAPALMQRLVKGLQRESVNIEEYQEKRDVLYNHLTSLG
FEIQKPQGAFYLFPKSPLADDLEFTRVALNHNILVVPGGGFGTPGYFRLSYCIEMDTIKRSLPAWTSLAQELGLK
>Mature_395_residues
MVLSDKVASSLGKASWIRKMFEEGDRLRKIYGPEKVFDFTLGNPSVEPPEKFNEQLKTLALNPEPGMHRYMSNAGYPETR
SAVAEVIAEQSDLPFTAQHIVMTVGAGGGLNVVLKAILNPGDEVIALSPYFVEYGFYVDNHGGVLKVVPNDEKFLPDLDA
IASAINEKTRAIIINSPNNPTGVVYPAETLASLGKLVTEKSQQWGRPIFVLSDEPYAKIVYDGVKVPSVFPYITNAIMVT
SHSKDLALPGERIGYIAVNPRINGVNQLVEGLIFCNRTLGFVNAPALMQRLVKGLQRESVNIEEYQEKRDVLYNHLTSLG
FEIQKPQGAFYLFPKSPLADDLEFTRVALNHNILVVPGGGFGTPGYFRLSYCIEMDTIKRSLPAWTSLAQELGLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=375, Percent_Identity=24, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI56713256, Length=375, Percent_Identity=23.4666666666667, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4507369, Length=319, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=25.9259259259259, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=26.0981912144703, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786816, Length=342, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=365, Percent_Identity=26.027397260274, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=319, Percent_Identity=24.4514106583072, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=367, Percent_Identity=23.433242506812, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=367, Percent_Identity=23.433242506812, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=332, Percent_Identity=24.3975903614458, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=26.4204545454545, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859735, Length=385, Percent_Identity=27.5324675324675, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=339, Percent_Identity=23.0088495575221, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646114, Length=339, Percent_Identity=23.0088495575221, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573067, Length=339, Percent_Identity=23.0088495575221, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573065, Length=339, Percent_Identity=23.0088495575221, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43579; Mature: 43579

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSDKVASSLGKASWIRKMFEEGDRLRKIYGPEKVFDFTLGNPSVEPPEKFNEQLKTLA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEE
LNPEPGMHRYMSNAGYPETRSAVAEVIAEQSDLPFTAQHIVMTVGAGGGLNVVLKAILNP
CCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCC
GDEVIALSPYFVEYGFYVDNHGGVLKVVPNDEKFLPDLDAIASAINEKTRAIIINSPNNP
CCCEEEECHHEEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCC
TGVVYPAETLASLGKLVTEKSQQWGRPIFVLSDEPYAKIVYDGVKVPSVFPYITNAIMVT
CEEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCCCHHHHHHCEEEEE
SHSKDLALPGERIGYIAVNPRINGVNQLVEGLIFCNRTLGFVNAPALMQRLVKGLQRESV
ECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
NIEEYQEKRDVLYNHLTSLGFEIQKPQGAFYLFPKSPLADDLEFTRVALNHNILVVPGGG
CHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCHHHHEEEECCCEEEEECCC
FGTPGYFRLSYCIEMDTIKRSLPAWTSLAQELGLK
CCCCCEEEEEEEEEHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MVLSDKVASSLGKASWIRKMFEEGDRLRKIYGPEKVFDFTLGNPSVEPPEKFNEQLKTLA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHEE
LNPEPGMHRYMSNAGYPETRSAVAEVIAEQSDLPFTAQHIVMTVGAGGGLNVVLKAILNP
CCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCC
GDEVIALSPYFVEYGFYVDNHGGVLKVVPNDEKFLPDLDAIASAINEKTRAIIINSPNNP
CCCEEEECHHEEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCC
TGVVYPAETLASLGKLVTEKSQQWGRPIFVLSDEPYAKIVYDGVKVPSVFPYITNAIMVT
CEEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCCCHHHHHHCEEEEE
SHSKDLALPGERIGYIAVNPRINGVNQLVEGLIFCNRTLGFVNAPALMQRLVKGLQRESV
ECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
NIEEYQEKRDVLYNHLTSLGFEIQKPQGAFYLFPKSPLADDLEFTRVALNHNILVVPGGG
CHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCHHHHEEEECCCEEEEECCC
FGTPGYFRLSYCIEMDTIKRSLPAWTSLAQELGLK
CCCCCEEEEEEEEEHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]