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The map label for this gene is ribB

Identifier: 134298645

GI number: 134298645

Start: 831882

End: 832535

Strand: Reverse

Name: ribB

Synonym: Dred_0778

Alternate gene names: 134298645

Gene position: 832535-831882 (Counterclockwise)

Preceding gene: 134298682

Following gene: 134298637

Centisome position: 23.07

GC content: 43.27

Gene sequence:

>654_bases
ATGAATCAGAGTTTACTAACTCAATTTGGTGACCCGTTTGAACGGGTAGAGAGAGCACTCCGATCTCTCCGAAACGGTAA
CGGGGTACTGGTTACAGATGACGAAAATCGGGAAAATGAAGGGGATCTAATATTCCCTGCTCAAACACTTAATGAAGTTC
AGATGGCTATGCTGATACGGGAGTGTAGTGGTATTGTTTGTCTTTGTCTGACCGATGAGAAAGTTCGTTCACTGGGTCTT
CCGATGATGGTAGAGAATAATTCAAGTCGGTTTAAAACTGCCTTTACTGTTACCATTGAAGCAGCTCACGGAGTAACGAC
TGGTGTTTCTGCGGCTGATCGGGTTAAAACTGTAAAAACAGCCGTTGCAGAAAATGCTAAACCTGAAGATCTTAACCGTC
CCGGTCATGTATTTCCTCTAAGAGCCTGCCCTGGTGGTGTACTGGAACGTCAGGGGCACACAGAAGCAACGGTAGATCTT
ATGAAATTGGCCGGACTTCAACCCTATGGTGTTCTCTGTGAGTTAACTAACATAGATGGTACTATGGCCCGCTTGCCCGA
AGTGGTAACCTTTGCTAATAAAAACAATATACCCGTGGTTACAATAGATGATTTAATCATGTATCGAAAACAACATCAAA
AGAAAGTAAGTTAA

Upstream 100 bases:

>100_bases
CAGGTATCCATTTCCTTATGCTGCTTGTGTAATACATTAGGCAGCTGTCTGTCTTTGCGCCCTGATTCTGGTAGATTAAT
CAACTAAAGGGGGATTTACC

Downstream 100 bases:

>100_bases
TAAACATTAATTTTAGCCCTTCGTTGAACGAAGGGCTAAAATTATGTTTTTAAGCCACAGATTATTCTGGTGGAATCTTG
ATTACCTCACTATTTTCCCC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNQSLLTQFGDPFERVERALRSLRNGNGVLVTDDENRENEGDLIFPAQTLNEVQMAMLIRECSGIVCLCLTDEKVRSLGL
PMMVENNSSRFKTAFTVTIEAAHGVTTGVSAADRVKTVKTAVAENAKPEDLNRPGHVFPLRACPGGVLERQGHTEATVDL
MKLAGLQPYGVLCELTNIDGTMARLPEVVTFANKNNIPVVTIDDLIMYRKQHQKKVS

Sequences:

>Translated_217_residues
MNQSLLTQFGDPFERVERALRSLRNGNGVLVTDDENRENEGDLIFPAQTLNEVQMAMLIRECSGIVCLCLTDEKVRSLGL
PMMVENNSSRFKTAFTVTIEAAHGVTTGVSAADRVKTVKTAVAENAKPEDLNRPGHVFPLRACPGGVLERQGHTEATVDL
MKLAGLQPYGVLCELTNIDGTMARLPEVVTFANKNNIPVVTIDDLIMYRKQHQKKVS
>Mature_217_residues
MNQSLLTQFGDPFERVERALRSLRNGNGVLVTDDENRENEGDLIFPAQTLNEVQMAMLIRECSGIVCLCLTDEKVRSLGL
PMMVENNSSRFKTAFTVTIEAAHGVTTGVSAADRVKTVKTAVAENAKPEDLNRPGHVFPLRACPGGVLERQGHTEATVDL
MKLAGLQPYGVLCELTNIDGTMARLPEVVTFANKNNIPVVTIDDLIMYRKQHQKKVS

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=217, Percent_Identity=67.741935483871, Blast_Score=315, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=42.512077294686, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_DESRM (A4J2L3)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001112141.1
- ProteinModelPortal:   A4J2L3
- SMR:   A4J2L3
- STRING:   A4J2L3
- GeneID:   4955452
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_0778
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- PhylomeDB:   A4J2L3
- BioCyc:   DRED349161:DRED_0778-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23867; Mature: 23867

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSLLTQFGDPFERVERALRSLRNGNGVLVTDDENRENEGDLIFPAQTLNEVQMAMLIR
CCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHH
ECSGIVCLCLTDEKVRSLGLPMMVENNSSRFKTAFTVTIEAAHGVTTGVSAADRVKTVKT
HCCCEEEEEECCHHHHHCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AVAENAKPEDLNRPGHVFPLRACPGGVLERQGHTEATVDLMKLAGLQPYGVLCELTNIDG
HHHCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TMARLPEVVTFANKNNIPVVTIDDLIMYRKQHQKKVS
HHHHCCHHEEECCCCCCCEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQSLLTQFGDPFERVERALRSLRNGNGVLVTDDENRENEGDLIFPAQTLNEVQMAMLIR
CCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHH
ECSGIVCLCLTDEKVRSLGLPMMVENNSSRFKTAFTVTIEAAHGVTTGVSAADRVKTVKT
HCCCEEEEEECCHHHHHCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AVAENAKPEDLNRPGHVFPLRACPGGVLERQGHTEATVDLMKLAGLQPYGVLCELTNIDG
HHHCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TMARLPEVVTFANKNNIPVVTIDDLIMYRKQHQKKVS
HHHHCCHHEEECCCCCCCEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA