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The map label for this gene is lutB [H]

Identifier: 134298308

GI number: 134298308

Start: 473997

End: 476165

Strand: Reverse

Name: lutB [H]

Synonym: Dred_0433

Alternate gene names: 134298308

Gene position: 476165-473997 (Counterclockwise)

Preceding gene: 134298310

Following gene: 134298307

Centisome position: 13.2

GC content: 43.29

Gene sequence:

>2169_bases
ATGGGAAGTCGGAGCGACAAAATTCAAAAGAATAAAGTAGCGTTAGGACTTCAAAATACCGATTCCCGTAAAGGTCGTTT
CAGAGCCTTTGACGCCATAAGACCAGCCATGAAGAAAATGGTAAAGAACTATCCCTATCTTTCCAATGAACTACGCCAAA
TTAAACAGCATTGTATTGATAACCTTGAGGAAATGATTTCTAAGGCAACGCTCTCCCTGGAAAGAAAGGGTTGCCATGTC
TACGTAGCTGAAACCACCGAACAAGCCCAAGCCCATTTATTAAGCCTCATCCCTCAAGGGGTTGTGGTAAAATCAAAGAC
CAATGCCGGAAAAGAAATAAACTTAACCCATGTCCTAGAAGAACGGGACATTCAAGTTATTGAAACAGATCTTGGTGACC
GAATTAATCAGCTAGCCCATAGTGAAGCAAGTCATTCCCTGGCACCGGCCATACATATTCCCATTGAAAAGGTTACAGAG
GTGTTCTCAAAGGAAATGGGAACACAATTGGAATGCAGTCATGAGGCCCTGGTGGTAGCAGCCCGTAAGGGATTACGGGA
CTATTTGATTAACGCAGACGTTGGCATTTCCGGAGCCAATGCCATAGCAGCCGATACAGGAAGTGTTTTTGTAACAGAAA
ATGAGGGAAATATCCGCGCAGTAACCATGATGCCAAAAATCCATATCGTAATTGCCGGAGTAGAAAAAATAGTACCTACC
TTGGAAGATGCTTTAAAGGTTGTCCGTTCTGCTGCAGTTTATGGCGTGGGACAGGATATCGGAACCTATGTTTCTGTTAT
ATCCGGTACCAGTACCTGCTGTGATCCTGAATTAGATGAATTAATACATGGCCAAGGCCCCCAAGAAGTTCACATCTTAT
TTCTAAAACATGGTCGACAAGAGGCCATCGATAAAGGTTTTGCTGAGTCCCTCTATTGCATCAATTGCGGAAGCTGCTTA
AATTTCTGCCCAATTTATGCTGAGATCGGTGAGAAATATGGTTACAAATATTTAGGCGGTCGGGGCTTGGTATTTACTGC
CTTTCATGGAGATCTTCAAAAGACCGTGGAAAGCGGCTTATCACTCTGCATTGGCTGCCAAAAGTGTAAAAACTCCTGCC
CGGTCCAAATGAATACACCGGAAATGCTTAAAAATTTACGTCAAGAACAGGTGCAGCAGGAGGGACTGGGTTGGAAAAAA
GAAAGGATGTTAGCTTTACTTAGCAAGCCCAAGGGCTTACCAAGATTAACAAAAGTGGCTTCCACGTTCGGTGGAACGTT
ATTAAAGAAAAGTAAAATAGGTGTAAAGACAAGATTTTCTTTACCATCCTTAGGGTTACCCGGTGAACGCTTACTTCCTG
CGGTGCAGAAAAAGTCCTTTTTGGAAAATGCTAAGCCAAAACCCATTGAAAACCCTGTAAAAACCGTGGCCTTTTTCCCG
GGCTGTGTGGTGAACTATACAGAACCCTCTGTGGGGGAAGCCCTTTTACATGTCCTGGGAGAAAATAAGGTTGCTGTAAA
ACTGGCCAAGGAAGACCTCTGCTGCGGTATCCCGGGTATTGTAAGTGGTGACAAAAACTACTCACGTCAAATGGCTTTAA
GGAACATAGAAATTTATAGCCAATTTGACACAGATGCACTGGTCTTTGTTTGCCCCAGTTGTGCTGTGGCCTTTAAAGAA
GAATACCCCAAATTATTTGCCAAGGATGACCCCAAACTCTTACAAAAAGTTATTAAGCTGGCTCAAAAGGTCAAAGACAT
TAACCAATTTTTGATAGAAGATATTGAATTAGTAACAATACCGGGGTCTATACCTGAGAAAATAACCTACCACGACCCCT
GTCACCTAGTTCGGAGTCTGGGCATCACACAACAACCAAGACAACTGATTCAAACCCTACCCGGGGCAAAGTTTGAAGAA
ATGGTGGATGCAGACGCCTGCTGCGGCTTTGGGGGGTCCTTTAGCATCGACTACTATGACCTATCCAGGCGAATTAATGA
AGGAAAATTAACATCAATTGAAAATACTGGGGCTACAATTTTGGCCACCAGTTGTCCCGGGTGCATGTTGCATTTTCGGG
ATGGCATAACCCAAAAGAATATGAAGCAGCAGGTTTTTCATACAATACAACTACTTAGTCAAACATATGGCAGGAGGAAT
AAGGAATGA

Upstream 100 bases:

>100_bases
ACGCCATTTTAAAGCAGAATATTCTTGAAAATAGTCTTTGCTAATTTTGTTTACTTTTTTGACATTTTAAAATTAATTTA
TTTGGAGGTGCATGCATGCT

Downstream 100 bases:

>100_bases
ATACCACGGCGAAAGCAGAAAAAATATTAGGGCAAATTCAAGCACAGCGGGAAACCTTGCTCGCCGACTATTCCACCCTA
GCACAGAAAGTTCAAAATTT

Product: CoB--CoM heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 721

Protein sequence:

>722_residues
MGSRSDKIQKNKVALGLQNTDSRKGRFRAFDAIRPAMKKMVKNYPYLSNELRQIKQHCIDNLEEMISKATLSLERKGCHV
YVAETTEQAQAHLLSLIPQGVVVKSKTNAGKEINLTHVLEERDIQVIETDLGDRINQLAHSEASHSLAPAIHIPIEKVTE
VFSKEMGTQLECSHEALVVAARKGLRDYLINADVGISGANAIAADTGSVFVTENEGNIRAVTMMPKIHIVIAGVEKIVPT
LEDALKVVRSAAVYGVGQDIGTYVSVISGTSTCCDPELDELIHGQGPQEVHILFLKHGRQEAIDKGFAESLYCINCGSCL
NFCPIYAEIGEKYGYKYLGGRGLVFTAFHGDLQKTVESGLSLCIGCQKCKNSCPVQMNTPEMLKNLRQEQVQQEGLGWKK
ERMLALLSKPKGLPRLTKVASTFGGTLLKKSKIGVKTRFSLPSLGLPGERLLPAVQKKSFLENAKPKPIENPVKTVAFFP
GCVVNYTEPSVGEALLHVLGENKVAVKLAKEDLCCGIPGIVSGDKNYSRQMALRNIEIYSQFDTDALVFVCPSCAVAFKE
EYPKLFAKDDPKLLQKVIKLAQKVKDINQFLIEDIELVTIPGSIPEKITYHDPCHLVRSLGITQQPRQLIQTLPGAKFEE
MVDADACCGFGGSFSIDYYDLSRRINEGKLTSIENTGATILATSCPGCMLHFRDGITQKNMKQQVFHTIQLLSQTYGRRN
KE

Sequences:

>Translated_722_residues
MGSRSDKIQKNKVALGLQNTDSRKGRFRAFDAIRPAMKKMVKNYPYLSNELRQIKQHCIDNLEEMISKATLSLERKGCHV
YVAETTEQAQAHLLSLIPQGVVVKSKTNAGKEINLTHVLEERDIQVIETDLGDRINQLAHSEASHSLAPAIHIPIEKVTE
VFSKEMGTQLECSHEALVVAARKGLRDYLINADVGISGANAIAADTGSVFVTENEGNIRAVTMMPKIHIVIAGVEKIVPT
LEDALKVVRSAAVYGVGQDIGTYVSVISGTSTCCDPELDELIHGQGPQEVHILFLKHGRQEAIDKGFAESLYCINCGSCL
NFCPIYAEIGEKYGYKYLGGRGLVFTAFHGDLQKTVESGLSLCIGCQKCKNSCPVQMNTPEMLKNLRQEQVQQEGLGWKK
ERMLALLSKPKGLPRLTKVASTFGGTLLKKSKIGVKTRFSLPSLGLPGERLLPAVQKKSFLENAKPKPIENPVKTVAFFP
GCVVNYTEPSVGEALLHVLGENKVAVKLAKEDLCCGIPGIVSGDKNYSRQMALRNIEIYSQFDTDALVFVCPSCAVAFKE
EYPKLFAKDDPKLLQKVIKLAQKVKDINQFLIEDIELVTIPGSIPEKITYHDPCHLVRSLGITQQPRQLIQTLPGAKFEE
MVDADACCGFGGSFSIDYYDLSRRINEGKLTSIENTGATILATSCPGCMLHFRDGITQKNMKQQVFHTIQLLSQTYGRRN
KE
>Mature_721_residues
GSRSDKIQKNKVALGLQNTDSRKGRFRAFDAIRPAMKKMVKNYPYLSNELRQIKQHCIDNLEEMISKATLSLERKGCHVY
VAETTEQAQAHLLSLIPQGVVVKSKTNAGKEINLTHVLEERDIQVIETDLGDRINQLAHSEASHSLAPAIHIPIEKVTEV
FSKEMGTQLECSHEALVVAARKGLRDYLINADVGISGANAIAADTGSVFVTENEGNIRAVTMMPKIHIVIAGVEKIVPTL
EDALKVVRSAAVYGVGQDIGTYVSVISGTSTCCDPELDELIHGQGPQEVHILFLKHGRQEAIDKGFAESLYCINCGSCLN
FCPIYAEIGEKYGYKYLGGRGLVFTAFHGDLQKTVESGLSLCIGCQKCKNSCPVQMNTPEMLKNLRQEQVQQEGLGWKKE
RMLALLSKPKGLPRLTKVASTFGGTLLKKSKIGVKTRFSLPSLGLPGERLLPAVQKKSFLENAKPKPIENPVKTVAFFPG
CVVNYTEPSVGEALLHVLGENKVAVKLAKEDLCCGIPGIVSGDKNYSRQMALRNIEIYSQFDTDALVFVCPSCAVAFKEE
YPKLFAKDDPKLLQKVIKLAQKVKDINQFLIEDIELVTIPGSIPEKITYHDPCHLVRSLGITQQPRQLIQTLPGAKFEEM
VDADACCGFGGSFSIDYYDLSRRINEGKLTSIENTGATILATSCPGCMLHFRDGITQKNMKQQVFHTIQLLSQTYGRRNK
E

Specific function: Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofi

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=461, Percent_Identity=31.4533622559653, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI1788576, Length=415, Percent_Identity=26.2650602409639, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI48994913, Length=413, Percent_Identity=22.7602905569007, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1786497, Length=240, Percent_Identity=24.5833333333333, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 79554; Mature: 79423

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRSDKIQKNKVALGLQNTDSRKGRFRAFDAIRPAMKKMVKNYPYLSNELRQIKQHCID
CCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NLEEMISKATLSLERKGCHVYVAETTEQAQAHLLSLIPQGVVVKSKTNAGKEINLTHVLE
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHH
ERDIQVIETDLGDRINQLAHSEASHSLAPAIHIPIEKVTEVFSKEMGTQLECSHEALVVA
HCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHHHHH
ARKGLRDYLINADVGISGANAIAADTGSVFVTENEGNIRAVTMMPKIHIVIAGVEKIVPT
HHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCEEEEEEECHHHHHHH
LEDALKVVRSAAVYGVGQDIGTYVSVISGTSTCCDPELDELIHGQGPQEVHILFLKHGRQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEEECCCH
EAIDKGFAESLYCINCGSCLNFCPIYAEIGEKYGYKYLGGRGLVFTAFHGDLQKTVESGL
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHHHHHHHHH
SLCIGCQKCKNSCPVQMNTPEMLKNLRQEQVQQEGLGWKKERMLALLSKPKGLPRLTKVA
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHH
STFGGTLLKKSKIGVKTRFSLPSLGLPGERLLPAVQKKSFLENAKPKPIENPVKTVAFFP
HHHCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
GCVVNYTEPSVGEALLHVLGENKVAVKLAKEDLCCGIPGIVSGDKNYSRQMALRNIEIYS
CCEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHEEE
QFDTDALVFVCPSCAVAFKEEYPKLFAKDDPKLLQKVIKLAQKVKDINQFLIEDIELVTI
CCCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
PGSIPEKITYHDPCHLVRSLGITQQPRQLIQTLPGAKFEEMVDADACCGFGGSFSIDYYD
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHCCCCCCCEEEHHH
LSRRINEGKLTSIENTGATILATSCPGCMLHFRDGITQKNMKQQVFHTIQLLSQTYGRRN
HHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
KE
CC
>Mature Secondary Structure 
GSRSDKIQKNKVALGLQNTDSRKGRFRAFDAIRPAMKKMVKNYPYLSNELRQIKQHCID
CCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NLEEMISKATLSLERKGCHVYVAETTEQAQAHLLSLIPQGVVVKSKTNAGKEINLTHVLE
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHH
ERDIQVIETDLGDRINQLAHSEASHSLAPAIHIPIEKVTEVFSKEMGTQLECSHEALVVA
HCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHHHHH
ARKGLRDYLINADVGISGANAIAADTGSVFVTENEGNIRAVTMMPKIHIVIAGVEKIVPT
HHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCEEEEEEECHHHHHHH
LEDALKVVRSAAVYGVGQDIGTYVSVISGTSTCCDPELDELIHGQGPQEVHILFLKHGRQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEEECCCH
EAIDKGFAESLYCINCGSCLNFCPIYAEIGEKYGYKYLGGRGLVFTAFHGDLQKTVESGL
HHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHHHHHHHHH
SLCIGCQKCKNSCPVQMNTPEMLKNLRQEQVQQEGLGWKKERMLALLSKPKGLPRLTKVA
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHH
STFGGTLLKKSKIGVKTRFSLPSLGLPGERLLPAVQKKSFLENAKPKPIENPVKTVAFFP
HHHCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
GCVVNYTEPSVGEALLHVLGENKVAVKLAKEDLCCGIPGIVSGDKNYSRQMALRNIEIYS
CCEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHEEE
QFDTDALVFVCPSCAVAFKEEYPKLFAKDDPKLLQKVIKLAQKVKDINQFLIEDIELVTI
CCCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
PGSIPEKITYHDPCHLVRSLGITQQPRQLIQTLPGAKFEEMVDADACCGFGGSFSIDYYD
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHCCCCCCCEEEHHH
LSRRINEGKLTSIENTGATILATSCPGCMLHFRDGITQKNMKQQVFHTIQLLSQTYGRRN
HHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]