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The map label for this gene is tig

Identifier: 13357907

GI number: 13357907

Start: 393527

End: 394876

Strand: Direct

Name: tig

Synonym: UU347

Alternate gene names: 13357907

Gene position: 393527-394876 (Clockwise)

Preceding gene: 13357906

Following gene: 13357908

Centisome position: 52.35

GC content: 27.41

Gene sequence:

>1350_bases
ATGAAATTACTAAATAAAATTAAGAACGAAAATGCGATTGAATTTCAAATTTTAATTGAAAAATCAGAATGAGAGAAAAA
ACACAAAGAATCATTTGAAAAAATTGCAAAAAAAACAGCTTCAAAATTAAAAATTCCTGGTTTTCGTCCAGGAAAAGTTC
CGGTTGAAGAAGCTAAAAAACACGTTAATGAAATTGAAGTTTTTGAAACAACAACAAATGATTTAATACCGCAAGTTTTA
ACTTTTTTAGAACAAGATGAATCATTTATAAATGATGATTCAGAAACTGTTGACACTCCAAGTGTTGATATATTAGATTT
TAAAGATGGAGAACTAAGTTTAAAAGTTGTTTATGATTTATACCCTGTTGCGACAATTGAAAGTTATAACGATTTAATTT
TAACACCAATTGTGAATGAAGCTTTTGAACATGAAGTTAATGCTGAAATTGAACATGCATTAAATTCTAAATCACAAAGA
CGTGTTAAAGATGATAATGAATTCATTGAAAAAGGGGATGAAGTTCGATTTGATTTTAAAGGGATGATTGATAGTGTGCC
TTTTGAAGGTGGAAGTGCTAAAGATCATTTATTAACAATTGGATCTAATCAATTTATTCCAGGATTTGAAGATCAAATGA
TAGGTTTAAAAAAAGATGAACGTAAAAATATTAATGTTAAATTTCCAGATGATTATCATGCAACCGATTTAGCAGGCAAA
GCAGCAGTATTTGAAGTTTTTATCAAAGAAATTACAAATGTAAAGCCACAAGAATTAAATGATGAATTTGCTAAATCATT
TAATTTGCCTAATGTTAATACAGTTCAAGAATTAAAAGATTATATTCACAATCAAATTGTTTTAGCTAAACAAGAAAAGA
ATAGTGAACGTGCCTGATTAGAGATTGCTCAACAATTATTAGCTAAAGCAAAGATAACACCAATTCCTCAATCATTAATT
GATCGTGAAGTTTCAACATTAAGACAACAAGTTTTATCACAATTATCACAATATAAAATTGAATTAAAACAATATTTGGA
ATTTAGTAAAAAATCAGAAGCACAATTTCAAGAAGACTTGATAAGACAAGCTAAAGAAACTATAACTTTAGCACTGTTAG
TTGATGATATTGCTGAAACACAAAATATTGTTGTATCTGATGAAGAAGTTAAAGAACGTGTTGCGGAAATGGCTAAACTA
TACCAAGGGGAAGAACAAGCTGTTATTGAACAATTATCAAAAAATCCTGATGCTGTTAAAGAGTTCTTGTTACATAAAAA
AGTTGTTAATTATTTAATTGACTTAAACAAAAATAATCAGCCAAAAAATACAACTTTATCTTCAAAATAA

Upstream 100 bases:

>100_bases
AACTAATAAAAAAATCTTTATAAATGTTAAAATATAAAAATATTATGTAAACTTTATATTAACATACATGATGTAATAAA
CGTTAATTGGTGGAATATAT

Downstream 100 bases:

>100_bases
AGACAATCAAATAAGAATTAAAGAAAATTTAGGACAAAAAGGCAAAATCAATGTATAAAATTAGCACTCGTAATAATAGT
TTGCTAATTTTTATTTGTTT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKLLNKIKNENAIEFQILIEKSEWEKKHKESFEKIAKKTASKLKIPGFRPGKVPVEEAKKHVNEIEVFETTTNDLIPQVL
TFLEQDESFINDDSETVDTPSVDILDFKDGELSLKVVYDLYPVATIESYNDLILTPIVNEAFEHEVNAEIEHALNSKSQR
RVKDDNEFIEKGDEVRFDFKGMIDSVPFEGGSAKDHLLTIGSNQFIPGFEDQMIGLKKDERKNINVKFPDDYHATDLAGK
AAVFEVFIKEITNVKPQELNDEFAKSFNLPNVNTVQELKDYIHNQIVLAKQEKNSERAWLEIAQQLLAKAKITPIPQSLI
DREVSTLRQQVLSQLSQYKIELKQYLEFSKKSEAQFQEDLIRQAKETITLALLVDDIAETQNIVVSDEEVKERVAEMAKL
YQGEEQAVIEQLSKNPDAVKEFLLHKKVVNYLIDLNKNNQPKNTTLSSK

Sequences:

>Translated_449_residues
MKLLNKIKNENAIEFQILIEKSE*EKKHKESFEKIAKKTASKLKIPGFRPGKVPVEEAKKHVNEIEVFETTTNDLIPQVL
TFLEQDESFINDDSETVDTPSVDILDFKDGELSLKVVYDLYPVATIESYNDLILTPIVNEAFEHEVNAEIEHALNSKSQR
RVKDDNEFIEKGDEVRFDFKGMIDSVPFEGGSAKDHLLTIGSNQFIPGFEDQMIGLKKDERKNINVKFPDDYHATDLAGK
AAVFEVFIKEITNVKPQELNDEFAKSFNLPNVNTVQELKDYIHNQIVLAKQEKNSERA*LEIAQQLLAKAKITPIPQSLI
DREVSTLRQQVLSQLSQYKIELKQYLEFSKKSEAQFQEDLIRQAKETITLALLVDDIAETQNIVVSDEEVKERVAEMAKL
YQGEEQAVIEQLSKNPDAVKEFLLHKKVVNYLIDLNKNNQPKNTTLSSK
>Mature_449_residues
MKLLNKIKNENAIEFQILIEKSE*EKKHKESFEKIAKKTASKLKIPGFRPGKVPVEEAKKHVNEIEVFETTTNDLIPQVL
TFLEQDESFINDDSETVDTPSVDILDFKDGELSLKVVYDLYPVATIESYNDLILTPIVNEAFEHEVNAEIEHALNSKSQR
RVKDDNEFIEKGDEVRFDFKGMIDSVPFEGGSAKDHLLTIGSNQFIPGFEDQMIGLKKDERKNINVKFPDDYHATDLAGK
AAVFEVFIKEITNVKPQELNDEFAKSFNLPNVNTVQELKDYIHNQIVLAKQEKNSERA*LEIAQQLLAKAKITPIPQSLI
DREVSTLRQQVLSQLSQYKIELKQYLEFSKKSEAQFQEDLIRQAKETITLALLVDDIAETQNIVVSDEEVKERVAEMAKL
YQGEEQAVIEQLSKNPDAVKEFLLHKKVVNYLIDLNKNNQPKNTTLSSK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=379, Percent_Identity=30.0791556728232, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 51058; Mature: 51058

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLNKIKNENAIEFQILIEKSEEKKHKESFEKIAKKTASKLKIPGFRPGKVPVEEAKKH
CCHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VNEIEVFETTTNDLIPQVLTFLEQDESFINDDSETVDTPSVDILDFKDGELSLKVVYDLY
HHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEEEHH
PVATIESYNDLILTPIVNEAFEHEVNAEIEHALNSKSQRRVKDDNEFIEKGDEVRFDFKG
HHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCHHHHHCCCCEEEEHHH
MIDSVPFEGGSAKDHLLTIGSNQFIPGFEDQMIGLKKDERKNINVKFPDDYHATDLAGKA
HHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCEECCCCCCCHHHCCHH
AVFEVFIKEITNVKPQELNDEFAKSFNLPNVNTVQELKDYIHNQIVLAKQEKNSERALEI
HHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHH
AQQLLAKAKITPIPQSLIDREVSTLRQQVLSQLSQYKIELKQYLEFSKKSEAQFQEDLIR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKETITLALLVDDIAETQNIVVSDEEVKERVAEMAKLYQGEEQAVIEQLSKNPDAVKEF
HHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHH
LLHKKVVNYLIDLNKNNQPKNTTLSSK
HHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLLNKIKNENAIEFQILIEKSEEKKHKESFEKIAKKTASKLKIPGFRPGKVPVEEAKKH
CCHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VNEIEVFETTTNDLIPQVLTFLEQDESFINDDSETVDTPSVDILDFKDGELSLKVVYDLY
HHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEEEHH
PVATIESYNDLILTPIVNEAFEHEVNAEIEHALNSKSQRRVKDDNEFIEKGDEVRFDFKG
HHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCHHHHHCCCCEEEEHHH
MIDSVPFEGGSAKDHLLTIGSNQFIPGFEDQMIGLKKDERKNINVKFPDDYHATDLAGKA
HHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCEECCCCCCCHHHCCHH
AVFEVFIKEITNVKPQELNDEFAKSFNLPNVNTVQELKDYIHNQIVLAKQEKNSERALEI
HHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHH
AQQLLAKAKITPIPQSLIDREVSTLRQQVLSQLSQYKIELKQYLEFSKKSEAQFQEDLIR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAKETITLALLVDDIAETQNIVVSDEEVKERVAEMAKLYQGEEQAVIEQLSKNPDAVKEF
HHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHH
LLHKKVVNYLIDLNKNNQPKNTTLSSK
HHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA