Click here to switch to the map view.

The map label for this gene is efp

Identifier: 13357858

GI number: 13357858

Start: 340721

End: 341287

Strand: Direct

Name: efp

Synonym: UU298

Alternate gene names: 13357858

Gene position: 340721-341287 (Clockwise)

Preceding gene: 13357856

Following gene: 13357859

Centisome position: 45.33

GC content: 30.34

Gene sequence:

>567_bases
ATGGCAACAATTATTCAAGCAAAAGATTTACGTGCTGGCCACACTTTTTTATATAAAGGTAATATTTACCAAGTAATAGA
AAATTCGTTTAATAAAACAGCTATGCGTGAAGGAATTGTAAAATGTAAAGTTAAAAATTTACGTACTGGTGCAATCACTA
TTGAAGTTTTAACTGGAGAAAAACTTGAACAAGCAGTGATTGAAAAATCAAAAATGACTTTTAGTTATGATGATGGTAGT
GGTTATGTGTTTATGGATAATGATACATATGAACAAATTTCAATTCCTTACAGTCAATTAAGTTGAGAGAAAAATTTTAT
TGAGGAAGGTACTGAAGTAAGTGTTATGCGTTATGATGGTGAATTAATGGGTGTAAGTTTACCAGATCAATTAGTCGTAA
CAATTATTGAAGCAGAAGAAGCGGTTCAGGGTAATTCAGTTCAAAATGCTACAAAACGTGCATGATTAGAATCAAAATGA
GAGTTTCAAGTTCCACAATTTATTAAATCTGGTGAAAAAGTGATTATTAATCCATCAAATGGTCAATATGTAGGAAGAGC
TAAATAA

Upstream 100 bases:

>100_bases
TTGTATGAATATAAAACATAATAACCTTTTAAATACATAATAATGCTAATAATTAGGTTATAATTTTATATTATTTTTGT
AGAAATATGAGGTAATAATA

Downstream 100 bases:

>100_bases
TAATGCAGTACATTACCATTAATAATACAAAATCAGGGAAGATTTTAATCTCAAAATCAAATATTAAAAAGTTTATTGAA
CAAAAATTTAATTTGATTGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MATIIQAKDLRAGHTFLYKGNIYQVIENSFNKTAMREGIVKCKVKNLRTGAITIEVLTGEKLEQAVIEKSKMTFSYDDGS
GYVFMDNDTYEQISIPYSQLSWEKNFIEEGTEVSVMRYDGELMGVSLPDQLVVTIIEAEEAVQGNSVQNATKRAWLESKW
EFQVPQFIKSGEKVIINPSNGQYVGRAK

Sequences:

>Translated_188_residues
MATIIQAKDLRAGHTFLYKGNIYQVIENSFNKTAMREGIVKCKVKNLRTGAITIEVLTGEKLEQAVIEKSKMTFSYDDGS
GYVFMDNDTYEQISIPYSQLS*EKNFIEEGTEVSVMRYDGELMGVSLPDQLVVTIIEAEEAVQGNSVQNATKRA*LESK*
EFQVPQFIKSGEKVIINPSNGQYVGRAK
>Mature_187_residues
ATIIQAKDLRAGHTFLYKGNIYQVIENSFNKTAMREGIVKCKVKNLRTGAITIEVLTGEKLEQAVIEKSKMTFSYDDGSG
YVFMDNDTYEQISIPYSQLS*EKNFIEEGTEVSVMRYDGELMGVSLPDQLVVTIIEAEEAVQGNSVQNATKRA*LESK*E
FQVPQFIKSGEKVIINPSNGQYVGRAK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=28.3422459893048, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790590, Length=189, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20609; Mature: 20478

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIIQAKDLRAGHTFLYKGNIYQVIENSFNKTAMREGIVKCKVKNLRTGAITIEVLTGE
CCEEEECCCCCCCCEEEEECCCCEEHHCCCCHHHHHCCCEEEEECCEEECEEEEEEECCC
KLEQAVIEKSKMTFSYDDGSGYVFMDNDTYEQISIPYSQLSEKNFIEEGTEVSVMRYDGE
HHHHHHHHHHCEEEEEECCCEEEEECCCCCEEEECCHHHHCCHHHHCCCCEEEEEEECCE
LMGVSLPDQLVVTIIEAEEAVQGNSVQNATKRALESKEFQVPQFIKSGEKVIINPSNGQY
EEEECCCHHHEEEEEEHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCE
VGRAK
EECCC
>Mature Secondary Structure 
ATIIQAKDLRAGHTFLYKGNIYQVIENSFNKTAMREGIVKCKVKNLRTGAITIEVLTGE
CEEEECCCCCCCCEEEEECCCCEEHHCCCCHHHHHCCCEEEEECCEEECEEEEEEECCC
KLEQAVIEKSKMTFSYDDGSGYVFMDNDTYEQISIPYSQLSEKNFIEEGTEVSVMRYDGE
HHHHHHHHHHCEEEEEECCCEEEEECCCCCEEEECCHHHHCCHHHHCCCCEEEEEEECCE
LMGVSLPDQLVVTIIEAEEAVQGNSVQNATKRALESKEFQVPQFIKSGEKVIINPSNGQY
EEEECCCHHHEEEEEEHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCE
VGRAK
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA