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The map label for this gene is infC

Identifier: 13357787

GI number: 13357787

Start: 274434

End: 274970

Strand: Direct

Name: infC

Synonym: UU227

Alternate gene names: 13357787

Gene position: 274434-274970 (Clockwise)

Preceding gene: 13357786

Following gene: 13357788

Centisome position: 36.51

GC content: 27.19

Gene sequence:

>537_bases
ATGTCATCAAATAATGATGCACGTAAAAATCAACCTTTAATTAATGATCAAATTCGTTTTCGAACAATGGTTGTAATTGA
TGACCATGGTAATAATTTAGGTGAAATGAATCGTATTGATGCCCTTAATTTAGCCGCTTCAAAGAATTTAGATTTAGTTG
TTATTGCTAAAAAAGGAAATATTCCTGTAACAAAAATTTTAGATTATGGTAAGTACAAATACGAACAAAAACGTCGTCAA
AAAGAATCAAGAAAAAATCAAACAATTATTAAGGTAAAAGAAATCAAAATTAAACCAATGATTGGTGAACATGATTTAAA
AGTAAGAGCAGAAAATGCTAAACGTTGATTAGAAGATAAAGACAACGTGAAATTTGTGATTGAAGCACGTGGACGTATGT
GTACAAAAGATGAATTTATTGTACAAGCTTATGAAAAATTCATTGACTTAATTAAAGATTATGGTACAGTTGTTCAAGCT
AATAAAAAAGTTAGCAATTATCGATATGAAACAATTATTGAACCAATTAAAAAATAA

Upstream 100 bases:

>100_bases
ATTACATCATTTATTCATGTTATAGATATAAATGATTTTCTTTATACATTTAATTTTTAATTAGGAGTGTTTAATGAATA
CACCAAACAATCAACGCCAT

Downstream 100 bases:

>100_bases
GGAAGGTAACTATAATGGCTAAAATTAGACAAAAAACAAAAAGAGCTGTTGCAAAACGTTTTAGTATTACAAAAAATGGT
AAATTAAAACGTAAACACGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGKYKYEQKRRQ
KESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKRWLEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQA
NKKVSNYRYETIIEPIKK

Sequences:

>Translated_178_residues
MSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGKYKYEQKRRQ
KESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKR*LEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQA
NKKVSNYRYETIIEPIKK
>Mature_177_residues
SSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGKYKYEQKRRQK
ESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKR*LEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQAN
KKVSNYRYETIIEPIKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=31.3953488372093, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20608; Mature: 20477

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGN
CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCC
IPVTKILDYGKYKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKRLEDKD
CCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEEECCHHCCCCCC
NVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQANKKVSNYRYETIIEPIKK
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGN
CCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCC
IPVTKILDYGKYKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKRLEDKD
CCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEEECCHHCCCCCC
NVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQANKKVSNYRYETIIEPIKK
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]