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The map label for this gene is gph

Identifier: 13357672

GI number: 13357672

Start: 150787

End: 151527

Strand: Direct

Name: gph

Synonym: UU115

Alternate gene names: 13357672

Gene position: 150787-151527 (Clockwise)

Preceding gene: 13357671

Following gene: 13357675

Centisome position: 20.06

GC content: 23.75

Gene sequence:

>741_bases
ATGTTTATGATAATTTTATTGTTAATTATTATTCAAATAAGAAGGAAAAATAAAAGATTTATGACCAAAAAACTGATTGT
TTTTGATTTTGATGGTACAATTATGCACACGCATACAACTATGAGCCTATCTATTATTGGTGTTTTAGAATTTTATAATC
ATCATATACCAAGTTTAAAAGAAATGAACGATCTGTTAGGTAATCTTTCTATGGTAAATATTTTTAAAAAGTATGCTAAA
CACGATCTTTTAAATATCGAAATTGAAATGATGATTTCTAAATATTATGAAATATATGAATCTTCGCTTTTTATGATCCA
TAGTTATTTTTTTGATGGTATTTTAGACCTAATCAAAAAATTAAAATCACTTAATAATAATGTTAAATTAGCAATTTTAT
CAAATAAACGATCTTCTTTATTAGCAACAATGGTTGATTATTATAATTTACGACCTTATTTTGATTATATTTTTGGTGCT
GAAGATGTCGAACAAATGAAGCCAGATCCTAGTGGTTTACTAAAAATTATGAACAACTGTAATGTTGATCATAAAAATAC
TTTATTGATTGGTGATAGTATAGCTGATTTAAAAGCAGCTATAAATGCTAATTGTCATTTTATTTTAGTTAATTGAGAAC
CACAATATCAAAAGCACATGGAAACAATTATTAATTTAAAACCTCTTATTGTTAAAACAATTGATGAACTAGAAACACAA
ATTAACCACTTTTTATATTAA

Upstream 100 bases:

>100_bases
GCTTATGCAGATGTTTTAATTGTTTCTGTATTAAAAGATTATTATGATTGTGATCTATACATGAAAGTTGATTATAATAA
TTTTAATTTAGATAAACAAG

Downstream 100 bases:

>100_bases
TGAACAAAAATGGCACAAAAAAGACTAGTTTATTATATAATATATAAGTGCTAGTTGCAGATGTAGTTCAATGGTAGAAC
GCAACCTTGCCAAGGTCGAG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 1; PGPase 1 [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MFMIILLLIIIQIRRKNKRFMTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAK
HDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGA
EDVEQMKPDPSGLLKIMNNCNVDHKNTLLIGDSIADLKAAINANCHFILVNWEPQYQKHMETIINLKPLIVKTIDELETQ
INHFLY

Sequences:

>Translated_246_residues
MFMIILLLIIIQIRRKNKRFMTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAK
HDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGA
EDVEQMKPDPSGLLKIMNNCNVDHKNTLLIGDSIADLKAAINANCHFILVN*EPQYQKHMETIINLKPLIVKTIDELETQ
INHFLY
>Mature_246_residues
MFMIILLLIIIQIRRKNKRFMTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAK
HDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGA
EDVEQMKPDPSGLLKIMNNCNVDHKNTLLIGDSIADLKAAINANCHFILVN*EPQYQKHMETIINLKPLIVKTIDELETQ
INHFLY

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 28644; Mature: 28644

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMIILLLIIIQIRRKNKRFMTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLK
CHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCEEEEEEEEHHHHHHHHHHHHHCCCCCHH
EMNDLLGNLSMVNIFKKYAKHDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKK
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNC
HHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHCC
NVDHKNTLLIGDSIADLKAAINANCHFILVNEPQYQKHMETIINLKPLIVKTIDELETQI
CCCCCCEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
NHFLY
HHHCC
>Mature Secondary Structure
MFMIILLLIIIQIRRKNKRFMTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLK
CHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCEEEEEEEEHHHHHHHHHHHHHCCCCCHH
EMNDLLGNLSMVNIFKKYAKHDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKK
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNC
HHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHCC
NVDHKNTLLIGDSIADLKAAINANCHFILVNEPQYQKHMETIINLKPLIVKTIDELETQI
CCCCCCEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
NHFLY
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]