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The map label for this gene is lrp [C]

Identifier: 126701168

GI number: 126701168

Start: 4139421

End: 4139849

Strand: Direct

Name: lrp [C]

Synonym: CD3544

Alternate gene names: 126701168

Gene position: 4139421-4139849 (Clockwise)

Preceding gene: 126701167

Following gene: 126701206

Centisome position: 96.48

GC content: 32.63

Gene sequence:

>429_bases
ATGGATGTTACAGATTACAGAATCATAGAAATTTTACAGGATGATGGGAGAATTTCTATGAAGGACTTAGGAAAAATAGT
TGGTTTAACTTCTCCTGCAGTTTCAGAAAGAGTCAAAAGATTAGAAGAGTCTGGTGTTATAGAAGGATATAAAGCTATTG
TCAACCCAGATTCATTAGGCAGAGTTATAAAGGCATTTATTCATATTTCTCTTCCAAGCAATGGATATACAGAATTTATT
GAGTCAGCTGCAAAGGACCCTAGGATTGTAGAATGTCACCATATAACAGGTGATGATTGCTTACTTTTAAAAGTAATTGT
AAAAGATATGTACGAGCTAGAAAATGTGATTGATACTATAAAGAAAATTGGTTCTACTAAGACCTCTGTTATACTATCAA
CGCCAATACAAGCAAAATCAATATTGTAA

Upstream 100 bases:

>100_bases
TGATTTATCTAGAAATCTTTGGTATTTAAAAACACAAATGATAGATTCTAAAAAAGTTTTATAGCATTAATTATTTTTAT
TTAAGGGGGACTGTTTATTT

Downstream 100 bases:

>100_bases
TATAAATTAAATACTAATGGTTTATTAATTAATAGACCATTAAGTATCCTTAATAAAATTTCAATTTTTGATATAAAAAA
AGTTGTCTTTCATAATTTTA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFI
ESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL

Sequences:

>Translated_142_residues
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFI
ESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL
>Mature_142_residues
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFI
ESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=34.2281879194631, Blast_Score=81, Evalue=3e-17,
Organism=Escherichia coli, GI1790182, Length=141, Percent_Identity=29.0780141843972, Blast_Score=63, Evalue=9e-12,
Organism=Escherichia coli, GI87081742, Length=113, Percent_Identity=29.2035398230088, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 15697; Mature: 15697

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLG
CCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHH
RVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTI
HHHHHHHHEECCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KKIGSTKTSVILSTPIQAKSIL
HHHCCCCCEEEEECCCCHHCCC
>Mature Secondary Structure
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLG
CCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHH
RVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTI
HHHHHHHHEECCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KKIGSTKTSVILSTPIQAKSIL
HHHCCCCCEEEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA