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The map label for this gene is yybE [H]

Identifier: 126700325

GI number: 126700325

Start: 3136409

End: 3137290

Strand: Direct

Name: yybE [H]

Synonym: CD2711

Alternate gene names: 126700325

Gene position: 3136409-3137290 (Clockwise)

Preceding gene: 126700319

Following gene: 126700333

Centisome position: 73.11

GC content: 28.8

Gene sequence:

>882_bases
TTGAATTTATATCACTTACGCTATTTTGTTACATTGGCACATTTAGAACACTATACAAAAGCGGCAGAAAATTTATCTAT
AACACAACCAAGCTTAAGTCATGCTATTTCTTTACTAGAAAATGAACTTGGGGTGGCTCTATTTGAAAAAGAAGGTAGAA
ATATAGTCCTTACTAAGTATGGAAAAATATTTTTAAAAGATGTGGAAAAATCATTAGAAATTTTAGATTCAAGTGTAAAA
TCATTAAAAATAACTGGTACTGGTGAAGGACAAATAGACTTAGCTTTTCTTAGAACACTTGGTACTGATTTTATCCCAGA
CATAGTGCATAAATTTTTAAAATCTAATCCTGCTAAATCAATAGATTTTAAATTTCATACTGGTGTAACTACTGACATTA
TTCAAGGTCTTAAAGAAAGAAAATATGATATTGCATTTTGTTCGAAACTTGAAAAAGAAAAGGGAATTGAATTTATACCT
GTTGCCAAACAAGATTTAGTACTAATTGTACCATATAGTCATCCACTAGCTGCAAAGGATACTATAGATTTAAAAGAAAC
CATACCTTATCCTCAAATAGTATTTAATCAGAGAAGCGGTCTTAGATATATAATTGATGATATGTTTAAAAAAATAAATC
AACAGCCTAATATAGTCTATGAAGTAGAGGAAGACCAAGTAATTGCTGGATTAGTTGCAAAAAATTTCGGAATTGCTGTA
GTCCCAAATATGAATATGCTTAGCTTTACAAAAGTAAAAGTAATTCAGATTATTCACCCAAGTTGGGAAAGAAACTTTTA
CTTAGCATTTATAAAAGATAGATATTTGCCTCCTGCAATTAAAAACTTTAAAAACTTTGTCATTAAAAACGCTCAATTAT
AA

Upstream 100 bases:

>100_bases
TCTTACTCTATAATCATATATAATAAAAATGTAAAAATATCTTAAAGGTTAACTTCTACAAATATATAAATAAAAATACC
TATGAAAGGATGAACAAAAA

Downstream 100 bases:

>100_bases
TTTATTAATAAAGGGGTTATTTTTAAATATCCTCTTTTATTCTTTTTATAAAATAAAAAAATCTATACTTTTAAAAGTAT
AGATTCCTAACTGACAGTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELGVALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVK
SLKITGTGEGQIDLAFLRTLGTDFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNIVYEVEEDQVIAGLVAKNFGIAV
VPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYLPPAIKNFKNFVIKNAQL

Sequences:

>Translated_293_residues
MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELGVALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVK
SLKITGTGEGQIDLAFLRTLGTDFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNIVYEVEEDQVIAGLVAKNFGIAV
VPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYLPPAIKNFKNFVIKNAQL
>Mature_293_residues
MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELGVALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVK
SLKITGTGEGQIDLAFLRTLGTDFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNIVYEVEEDQVIAGLVAKNFGIAV
VPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYLPPAIKNFKNFVIKNAQL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=27.1477663230241, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=26.7605633802817, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=27.9863481228669, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=24.5614035087719, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=26.0869565217391, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=23.6111111111111, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790399, Length=288, Percent_Identity=21.5277777777778, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=21.0344827586207, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789204, Length=258, Percent_Identity=22.4806201550388, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=243, Percent_Identity=24.2798353909465, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=24.3137254901961, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=23.7154150197628, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=24.21875, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33444; Mature: 33444

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELGVALFEKEGRNIVLTKY
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEEEEC
GKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGTDFIPDIVHKFLKSNPAKS
CHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCE
IDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIPVAKQDLVLIVPYSHPLAAKD
EEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCC
TIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNIVYEVEEDQVIAGLVAKNFGIAV
CCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCEEE
VPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYLPPAIKNFKNFVIKNAQL
ECCCCCEEEHHEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELGVALFEKEGRNIVLTKY
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEEEEC
GKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGTDFIPDIVHKFLKSNPAKS
CHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCE
IDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIPVAKQDLVLIVPYSHPLAAKD
EEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCC
TIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNIVYEVEEDQVIAGLVAKNFGIAV
CCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCEEE
VPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYLPPAIKNFKNFVIKNAQL
ECCCCCEEEHHEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]