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The map label for this gene is int [H]

Identifier: 126699683

GI number: 126699683

Start: 2380942

End: 2382054

Strand: Direct

Name: int [H]

Synonym: CD2066

Alternate gene names: 126699683

Gene position: 2380942-2382054 (Clockwise)

Preceding gene: 126699681

Following gene: 126699723

Centisome position: 55.5

GC content: 24.62

Gene sequence:

>1113_bases
ATGAATGCATTTATTAGAAAAAGAAATAAAAACTATGTTGTTTACCTGGAATTTGAAGATGAAAAGACAGGTAAAAGAAA
ACAAAAAAATATGGGTACTTTTGATAAAAAAAGGGAAGCAAGTAAAAGACTAAATGAGGTAAAAGAAAGCTTATATAATG
ATGGTTTTTTAGTACCAAGCGAAATTACAGTGTCAGAATTTCTATTAGATTTTCTAAATAAATATAGTGAAAATATATCT
TTAGCTACATATAATAATTATGTTAGTATTTGTAAGAATTACATTAATCCATCTATTGGAAAATATAAAATACAAGACTT
ACATCCGGTTCACATACAAAACTACATAGATAAACTATCTTATAAACTAAATCCTCAATCAATTAAGATTCATATAAATA
TATTGAAACTTGCAATAAAAAGAGCTTATAGACTCAAATTAATAAAAGAAAATGTTATGGATAGTATAAAGGCTCCAAGA
TATAAAAAATTTAAAAATGAGATTTATGATAGAGAACAAATGATAAAATTATTAGATTTAGCAAAAAATACAGAAATGGA
ATTACCTATTAATTTGGCTATTGGATTAGGTCTTAGAATTTCAGAAGTTTTAGGTCTAACTTGGGATAATATTGATTTTG
AAGAAAATACAATAACAGTAAATAAGATAACTTCCCGAATTAATGGTTCTGTTATTCTCAAAGAGCCAAAGACAGAAAGC
TCTGTTAGAAAAATATCTTCTCCCAAAGAATTAATGTCTTTATTAAAAGAATATAAAATAAAACAGAATAAAAATTTATT
AAAATCTTCCATTAGAAATAATAATAATTTGTTGTTTTTCAATAAGAAATGTGAACCTATTGCTGAAGATGTTATGAGTA
AAAAATTTAAAAGATTTTTAGAAAAGAATGAATTACCTCATATTAGATTCCATGATTTAAGACACTCACATGTTACTTTA
CTTATAAATTCTAAAGTACCTATAAAGGTTATATCCGAGAGAGTAGGACACTCAAATATAAGTACTACTCTAAGCGTTTA
TTCTCATGTACTTAAAGAAATGGATAAAGAGGCTTCTGACAAAATTTCTGAAAGTTTATTTAATGCTAATTAA

Upstream 100 bases:

>100_bases
ATATACAATGTATTAAAATGTATGCAACTCTATTTCAAAATTATTTTGTGATATATATATGTTATAATAAATGTATAAAA
TTTTGATTGGTGGGTTACAT

Downstream 100 bases:

>100_bases
TATTAATTTATCTTAGCTTTAAATTAGCTTAGCTTATTGAGATAGATTCATTAATATTAAATGTATCTATCTCAAATTAA
TAACTACTTAAATAATCTGT

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRLNEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENIS
LATYNNYVSICKNYINPSIGKYKIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIKAPR
YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTES
SVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTL
LINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN

Sequences:

>Translated_370_residues
MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRLNEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENIS
LATYNNYVSICKNYINPSIGKYKIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIKAPR
YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTES
SVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTL
LINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN
>Mature_370_residues
MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRLNEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENIS
LATYNNYVSICKNYINPSIGKYKIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIKAPR
YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTES
SVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTL
LINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN

Specific function: Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=208, Percent_Identity=25.4807692307692, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43192; Mature: 43192

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRLNEVKESLYNDGFLVPS
CCCCCEECCCCEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKYKIQDLHPVHIQNYIDKLS
CCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
YKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIKAPRYKKFKNEIYDREQMIKLLDL
CEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHH
AKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTES
HCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCCEEEECCCCHH
SVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
EKNELPHIRFHDLRHSHVTLLINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASD
HHCCCCCEEHCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KISESLFNAN
HHHHHHHCCC
>Mature Secondary Structure
MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRLNEVKESLYNDGFLVPS
CCCCCEECCCCEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKYKIQDLHPVHIQNYIDKLS
CCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
YKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIKAPRYKKFKNEIYDREQMIKLLDL
CEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHH
AKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTES
HCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCCEEEECCCCHH
SVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
EKNELPHIRFHDLRHSHVTLLINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASD
HHCCCCCEEHCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KISESLFNAN
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]