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The map label for this gene is moaC [H]

Identifier: 126699321

GI number: 126699321

Start: 1988368

End: 1988838

Strand: Direct

Name: moaC [H]

Synonym: CD1714

Alternate gene names: 126699321

Gene position: 1988368-1988838 (Clockwise)

Preceding gene: 126699320

Following gene: 126699322

Centisome position: 46.35

GC content: 33.12

Gene sequence:

>471_bases
ATGTTAACACATATAAATGAAAAAGGGTATGCCAAGATGGTGGACATAAGTGAAAAAGATGATACTAAAAGAACGGCCGT
AGCTACAGCTACAATTACTCTTAGTAAGGAAGCATTAGAAAAAGTAAAAAATGGTCAGATAAAAAAAGGAGACGTATTGT
CTGTAGCTCAAGTTGCAGGTATAATGGGAGCTAAAAATACATCTTCAAACATACCAATGTGCCATCAGATTAAATTAGTT
GGATGTGATTTAGAATTTGATGTAGATGATTCTATGTCTGCTATTAAGATATACGCAACCTGTAAATCTCTTGGGAAAAC
TGGAGTAGAAATGGAAGCTTTAAATGCATGTTCTTTAGCAGCACTTACAATTTATGATATGTGTAAAGCAGTTGATAAAA
AAATGGTTATAAGTAATATCCATCTTGTAGAGAAGACTGGTGGAAAATCAGGAGATTTTAAGTTCGAGTAA

Upstream 100 bases:

>100_bases
TATGAAAGATATAATAAAACAAAAACCAGAAAAACATCATTTAATAGAAAATAAATGTAGTGATACAAATAGGCGTATGT
ATGAAATTGGAGGATAAGTA

Downstream 100 bases:

>100_bases
ATTAATAATATATTGGGTTAAAATTTGGAGGAAATATGGCGAAGGTAGTGTCAATAAATATAAGTGAGAAAAAAGGTGTA
ATTAAAGTTCCTGTACAATG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKNGQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLV
GCDLEFDVDDSMSAIKIYATCKSLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE

Sequences:

>Translated_156_residues
MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKNGQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLV
GCDLEFDVDDSMSAIKIYATCKSLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE
>Mature_156_residues
MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKNGQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLV
GCDLEFDVDDSMSAIKIYATCKSLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=50.3225806451613, Blast_Score=156, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI32566331, Length=150, Percent_Identity=50, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=46.4516129032258, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=46.5277777777778, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16796; Mature: 16796

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKNGQIKKGDVLSVAQVAG
CCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHH
IMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCKSLGKTGVEMEALNACSLA
HHCCCCCCCCCCEEEEEEEEECCEEECCCCCCCHHHHHEEHHHHCCCCCCHHHHCHHHHH
ALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKNGQIKKGDVLSVAQVAG
CCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHH
IMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCKSLGKTGVEMEALNACSLA
HHCCCCCCCCCCEEEEEEEEECCEEECCCCCCCHHHHHEEHHHHCCCCCCHHHHCHHHHH
ALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]